ESR Tubes Glass

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ESR Tubes Glass are specialized glass tubes (300 mm length, 2.55 mm bore diameter, graduated 0-200 mm in 1 mm intervals) meeting ICSH and CLSI Westergren specifications for measuring erythrocyte sedimentation rate, a non-specific marker of inflammation. Used with citrated or diluted EDTA blood, filled to exactly 200 mm, placed vertically in Westergren stand, and read at 60 minutes. Primary clinical applications include determination of ESR for diagnosing and monitoring inflammatory conditions (infections, autoimmune disorders, malignancies), monitoring disease activity in rheumatoid arthritis, assessment of temporal arteritis and polymyalgia rheumatica, evaluation of infection and inflammatory response, screening for occult inflammatory conditions, and monitoring chronic inflammatory diseases (SLE, IBD, vasculitis). Critical safety precautions include handling glass tubes carefully to avoid breakage (sharps hazard), proper disposal in sharps containers as biohazardous waste, ensuring vertical alignment and constant temperature (18-25°C), reading at exactly 60 minutes, and avoiding air bubbles and vibration. Essential consumable for reference Westergren ESR testing in clinical laboratories.

Categories: LABORATORY EQUIPMENT AND SUPPLIES, DIAGNOSTIC EQUIPMENT, Diagnostic Kits, Lab Consumables Tags: ESR Tubes, Glass ESR Pipettes, Hematology, Inflammation Marker, Sedimentation Rate Tubes, Westergren Method, Westergren Tubes

Description

ESR Tubes Glass

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Erythrocyte Sedimentation Rate (ESR) Determination:

Primary Use: Glass ESR tubes are specifically designed for measuring the rate at which erythrocytes sediment in a given time period (typically 1 hour), providing a non-specific marker of inflammation used in diagnosing and monitoring conditions such as infections, autoimmune disorders, and malignancies.
How it helps: Provides doctors with a simple, time-tested window into the body’s inflammatory state, revealing the presence of hidden inflammation that may be causing everything from joint pain to unexplained fever.

2. Westergren Method ESR Testing:

Primary Use: Standard glass tubes meeting Westergren specifications (length 300 mm, graduated in mm) are used in the reference Westergren method for ESR determination, which remains the gold standard for laboratory measurement of ESR.
How it helps: Ensures consistent, reliable results across laboratories worldwide by adhering to the internationally recognized reference method, giving doctors confidence that ESR results are accurate and comparable no matter where the test is performed.

3. Monitoring Disease Activity in Rheumatoid Arthritis:

Primary Use: Serial ESR measurements using standardized glass tubes help monitor disease activity and response to therapy in patients with rheumatoid arthritis and other inflammatory arthritides.
How it helps: Gives patients with arthritis and their rheumatologists objective feedback on whether treatments are working, helping guide adjustments that can slow disease progression and reduce pain.

4. Assessment of Temporal Arteritis and Polymyalgia Rheumatica:

Primary Use: ESR is a key diagnostic criterion for giant cell arteritis (temporal arteritis) and polymyalgia rheumatica, with markedly elevated ESR values supporting clinical diagnosis.
How it helps: Helps diagnose these serious inflammatory conditions quickly, allowing for prompt treatment that can prevent blindness in temporal arteritis and relieve the debilitating pain of polymyalgia rheumatica.

5. Evaluation of Infection and Inflammatory Response:

Primary Use: ESR helps differentiate bacterial from viral infections and monitor response to antibiotic therapy, though CRP is more rapidly responsive.
How it helps: Provides another piece of the diagnostic puzzle when evaluating patients with suspected infections, helping doctors distinguish between different types of illness and track recovery.

6. Screening for Occult Inflammatory Conditions:

Primary Use: ESR is often included in routine laboratory panels to screen for unsuspected inflammatory or malignant conditions in patients with constitutional symptoms (fever, weight loss, fatigue).
How it helps: Uncovers hidden causes of vague symptoms that might otherwise be dismissed, leading to earlier diagnosis of serious conditions like hidden infections, autoimmune diseases, or cancers.

7. Monitoring Chronic Inflammatory Diseases:

Primary Use: Serial ESR measurements are used to monitor disease activity in conditions such as systemic lupus erythematosus, inflammatory bowel disease, and vasculitis.
How it helps: Provides patients with chronic inflammatory conditions and their doctors a reliable way to track disease flares and remissions over time, guiding treatment decisions that maintain quality of life.

SECONDARY & SUPPORTIVE USES

1. Research and Clinical Trials: Used in studies investigating inflammatory markers and treatment efficacy, contributing to scientific understanding of inflammatory diseases and the development of new therapies.

2. Veterinary Medicine: Used for ESR determination in animal health, though reference ranges differ, helping veterinarians diagnose and monitor inflammatory conditions in pets and livestock.

3. Quality Control in Laboratory Testing: Standardized glass tubes ensure consistency in ESR measurement across laboratories, maintaining the reliability of this important diagnostic test.

4. Teaching and Training: Used in medical laboratory science education to teach the Westergren method, training the next generation of laboratory professionals in this essential technique.

5. Epidemiological Studies: Used in population-based studies to assess inflammatory burden, helping researchers understand the prevalence and impact of inflammation-related diseases in different populations.

6. Geriatric Assessment: ESR may be used in evaluation of unexplained constitutional symptoms in elderly patients, helping uncover hidden conditions in a vulnerable population.

7. Preoperative Assessment: Occasionally used to screen for occult infection or inflammation before surgery, helping identify patients who may be at increased risk for surgical complications.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Specialized glass tubes for measuring erythrocyte sedimentation rate by the Westergren method.
Common Names: ESR Tubes, Westergren Tubes, Sedimentation Rate Tubes, Glass ESR Pipettes, Westergren Pipettes.
Specifications (Westergren Standard):
- Length: 300 mm ± 1.5 mm.
- Graduations: 0-200 mm scale, marked at 1 mm intervals.
- Bore Diameter: 2.55 mm ± 0.15 mm.
- Volume: Approximately 1.0-1.5 mL.
Graduation Range: 0-200 mm (typical).
Zero Mark: At top of tube (0 mm) with 200 mm at bottom.
Material: Soda-lime glass or borosilicate glass; optically clear.
Markings: Permanent, fused ceramic or etched graduations.

2. TECHNICAL & PERFORMANCE PROPERTIES

Westergren Method Compliance: Meets International Council for Standardization in Haematology (ICSH) and CLSI specifications for reference ESR method.
Dimensional Accuracy: Length tolerance ±1.5 mm; bore diameter tolerance ±0.15 mm ensures consistent sedimentation characteristics.
Graduation Accuracy: ±0.5 mm at any point on scale.
Surface Properties: Clean, smooth inner surface prevents turbulence and ensures consistent settling.
Compatibility: Designed for use with Westergren sedimentation racks and stands.
Sample Type: Citrated blood (4:1 ratio) or EDTA blood diluted with saline (some methods).
Sedimentation Time: 60 minutes ± 1 minute standard reading; 30-minute reading used in some settings.
Temperature Stability: Readings standardized at 18-25°C; elevated temperatures increase rate.

3. PHYSICAL & OPERATIONAL PROPERTIES

Tube Dimensions: 300 mm length × 3-4 mm outer diameter.
Graduation Details: Clearly marked black or white ceramic graduations; major marks at 10 mm intervals, minor at 1 mm.
Identification Mark: Manufacturers often include logo or lot number on tube.
Packaging: Individually wrapped or bulk packed in protective containers to prevent breakage.
Shelf Life: Indefinite if stored properly; no expiration.
Storage: Store in original packaging at room temperature; protect from breakage and dust.
Cleaning: Tubes are single-use; not intended for reuse.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device; generally exempt from pre-market notification.
Quality Standards: Manufactured to ICSH and CLSI standards for ESR measurement.
Biohazard Precautions: Used tubes are contaminated with blood; dispose of biohazardous waste.
Breakage Hazard: Glass tubes are fragile and may break, creating sharp fragments.
Disposal: Dispose of used tubes in sharps containers as biohazardous waste.
Accuracy Certification: Some tubes certified for accuracy traceable to national standards.
Latex-Free: All components latex-free.

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store in original packaging at room temperature; protect from breakage, dust, and moisture.
Inspection: Before use, check for cracks, chips, or damaged graduations; do not use damaged tubes.
Filling: Fill to exactly 200 mm mark (0 mark at top) using Westergren pipette or syringe.
Setting Up: Place filled tube vertically in Westergren stand; ensure no air bubbles.
Reading: Read at exactly 60 minutes (or 30 minutes) at top of clear plasma column, ignoring buffy coat.
Disposal: After reading, dispose of the tube in a sharps container; do not reuse.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Measurement of erythrocyte sedimentation rate by the Westergren method for assessing inflammatory activity.
Proper Technique (Westergren Method):
1. Mix citrated blood (4:1 ratio) or dilute EDTA blood with saline.
2. Draw blood to exactly 200 mm mark (0 at top).
3. Place the tube vertically in Westergren stand at 18-25°C.
4. Allow to stand undisturbed for exactly 60 minutes.
5. Read distance from top of plasma column to top of sedimented red cells.
6. Report results in mm/hour.
Reference Ranges (Westergren):

Men <50 years: 0-15 mm/hour.
Men >50 years: 0-20 mm/hour.
Women <50 years: 0-20 mm/hour.
Women >50 years: 0-30 mm/hour.
Children: 0-10 mm/hour.

Limitations: Non-specific; affected by age, gender, anemia, polycythemia, and temperature; glass tubes fragile; requires 1 hour for result.

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Breakage Hazard: Glass tubes are fragile; handle with care to avoid breakage. If the tube breaks during filling or reading, carefully remove fragments with forceps; dispose in a sharps container.
Biohazard: Used tubes are contaminated with blood; dispose in sharps containers; never discard in regular trash.
Filling: Use appropriate safety devices (gloves, eye protection) when handling blood.
Vertical Alignment: Ensure tube is exactly vertical; angled tube increases sedimentation rate.
Temperature Control: Avoid drafts, direct sunlight, and temperature variations; results affected by temperature.
Timing: Read at exactly 60 minutes; delayed reading increases result.
Air Bubbles: Avoid air bubbles in column; bubbles interfere with sedimentation.
Vibration: Place stand on vibration-free surface; vibration increases sedimentation rate.

2. FIRST AID MEASURES

Broken Tube with Blood Exposure: If a broken tube causes a cut, wash wound thoroughly with soap and water; report injury; follow institutional bloodborne pathogen exposure protocol.
Blood Spill: Contain with absorbent material; disinfect area with 10% bleach solution.
Eye Contact with Blood: Flush eyes with copious water for 15 minutes; seek medical attention.

3. FIRE FIGHTING MEASURES

Flammability: Glass is non-combustible.
Extinguishing Media: Use water, foam, CO₂, or dry chemical as appropriate for surrounding fire.

ESR Tubes Glass

ESR Tubes Glass

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Erythrocyte Sedimentation Rate (ESR) Determination:

How it helps: Provides doctors with a simple, time-tested window into the body’s inflammatory state, revealing the presence of hidden inflammation that may be causing everything from joint pain to unexplained fever.

2. Westergren Method ESR Testing:

Primary Use: Standard glass tubes meeting Westergren specifications (length 300 mm, graduated in mm) are used in the reference Westergren method for ESR determination, which remains the gold standard for laboratory measurement of ESR.

How it helps: Ensures consistent, reliable results across laboratories worldwide by adhering to the internationally recognized reference method, giving doctors confidence that ESR results are accurate and comparable no matter where the test is performed.

3. Monitoring Disease Activity in Rheumatoid Arthritis:

Primary Use: Serial ESR measurements using standardized glass tubes help monitor disease activity and response to therapy in patients with rheumatoid arthritis and other inflammatory arthritides.

How it helps: Gives patients with arthritis and their rheumatologists objective feedback on whether treatments are working, helping guide adjustments that can slow disease progression and reduce pain.

4. Assessment of Temporal Arteritis and Polymyalgia Rheumatica:

Primary Use: ESR is a key diagnostic criterion for giant cell arteritis (temporal arteritis) and polymyalgia rheumatica, with markedly elevated ESR values supporting clinical diagnosis.

How it helps: Helps diagnose these serious inflammatory conditions quickly, allowing for prompt treatment that can prevent blindness in temporal arteritis and relieve the debilitating pain of polymyalgia rheumatica.

5. Evaluation of Infection and Inflammatory Response:

Primary Use: ESR helps differentiate bacterial from viral infections and monitor response to antibiotic therapy, though CRP is more rapidly responsive.

How it helps: Provides another piece of the diagnostic puzzle when evaluating patients with suspected infections, helping doctors distinguish between different types of illness and track recovery.

6. Screening for Occult Inflammatory Conditions:

Primary Use: ESR is often included in routine laboratory panels to screen for unsuspected inflammatory or malignant conditions in patients with constitutional symptoms (fever, weight loss, fatigue).

How it helps: Uncovers hidden causes of vague symptoms that might otherwise be dismissed, leading to earlier diagnosis of serious conditions like hidden infections, autoimmune diseases, or cancers.

7. Monitoring Chronic Inflammatory Diseases:

Primary Use: Serial ESR measurements are used to monitor disease activity in conditions such as systemic lupus erythematosus, inflammatory bowel disease, and vasculitis.

How it helps: Provides patients with chronic inflammatory conditions and their doctors a reliable way to track disease flares and remissions over time, guiding treatment decisions that maintain quality of life.

SECONDARY & SUPPORTIVE USES

1. Research and Clinical Trials: Used in studies investigating inflammatory markers and treatment efficacy, contributing to scientific understanding of inflammatory diseases and the development of new therapies.

2. Veterinary Medicine: Used for ESR determination in animal health, though reference ranges differ, helping veterinarians diagnose and monitor inflammatory conditions in pets and livestock.

3. Quality Control in Laboratory Testing: Standardized glass tubes ensure consistency in ESR measurement across laboratories, maintaining the reliability of this important diagnostic test.

4. Teaching and Training: Used in medical laboratory science education to teach the Westergren method, training the next generation of laboratory professionals in this essential technique.

5. Epidemiological Studies: Used in population-based studies to assess inflammatory burden, helping researchers understand the prevalence and impact of inflammation-related diseases in different populations.

6. Geriatric Assessment: ESR may be used in evaluation of unexplained constitutional symptoms in elderly patients, helping uncover hidden conditions in a vulnerable population.

7. Preoperative Assessment: Occasionally used to screen for occult infection or inflammation before surgery, helping identify patients who may be at increased risk for surgical complications.

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Specialized glass tubes for measuring erythrocyte sedimentation rate by the Westergren method.

Common Names: ESR Tubes, Westergren Tubes, Sedimentation Rate Tubes, Glass ESR Pipettes, Westergren Pipettes.

Specifications (Westergren Standard):

Length: 300 mm ± 1.5 mm.

Graduations: 0-200 mm scale, marked at 1 mm intervals.

Bore Diameter: 2.55 mm ± 0.15 mm.

Volume: Approximately 1.0-1.5 mL.

Graduation Range: 0-200 mm (typical).

Zero Mark: At top of tube (0 mm) with 200 mm at bottom.

Material: Soda-lime glass or borosilicate glass; optically clear.

Markings: Permanent, fused ceramic or etched graduations.

2. TECHNICAL & PERFORMANCE PROPERTIES

Westergren Method Compliance: Meets International Council for Standardization in Haematology (ICSH) and CLSI specifications for reference ESR method.

Dimensional Accuracy: Length tolerance ±1.5 mm; bore diameter tolerance ±0.15 mm ensures consistent sedimentation characteristics.

Graduation Accuracy: ±0.5 mm at any point on scale.

Surface Properties: Clean, smooth inner surface prevents turbulence and ensures consistent settling.

Compatibility: Designed for use with Westergren sedimentation racks and stands.

Sample Type: Citrated blood (4:1 ratio) or EDTA blood diluted with saline (some methods).

Sedimentation Time: 60 minutes ± 1 minute standard reading; 30-minute reading used in some settings.

Temperature Stability: Readings standardized at 18-25°C; elevated temperatures increase rate.

3. PHYSICAL & OPERATIONAL PROPERTIES

Tube Dimensions: 300 mm length × 3-4 mm outer diameter.

Graduation Details: Clearly marked black or white ceramic graduations; major marks at 10 mm intervals, minor at 1 mm.

Identification Mark: Manufacturers often include logo or lot number on tube.

Packaging: Individually wrapped or bulk packed in protective containers to prevent breakage.

Shelf Life: Indefinite if stored properly; no expiration.

Storage: Store in original packaging at room temperature; protect from breakage and dust.

Cleaning: Tubes are single-use; not intended for reuse.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device; generally exempt from pre-market notification.

Quality Standards: Manufactured to ICSH and CLSI standards for ESR measurement.

Biohazard Precautions: Used tubes are contaminated with blood; dispose of biohazardous waste.

Breakage Hazard: Glass tubes are fragile and may break, creating sharp fragments.

Disposal: Dispose of used tubes in sharps containers as biohazardous waste.

Accuracy Certification: Some tubes certified for accuracy traceable to national standards.

Latex-Free: All components latex-free.

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store in original packaging at room temperature; protect from breakage, dust, and moisture.

Inspection: Before use, check for cracks, chips, or damaged graduations; do not use damaged tubes.

Filling: Fill to exactly 200 mm mark (0 mark at top) using Westergren pipette or syringe.

Setting Up: Place filled tube vertically in Westergren stand; ensure no air bubbles.

Reading: Read at exactly 60 minutes (or 30 minutes) at top of clear plasma column, ignoring buffy coat.

Disposal: After reading, dispose of the tube in a sharps container; do not reuse.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Measurement of erythrocyte sedimentation rate by the Westergren method for assessing inflammatory activity.

Proper Technique (Westergren Method):

Mix citrated blood (4:1 ratio) or dilute EDTA blood with saline.

Draw blood to exactly 200 mm mark (0 at top).