Horizontal Electrophoresis

An Electrophoresis Bath is a laboratory instrument used to separate charged molecules (proteins, nucleic acids) through a gel medium using an electric current, based on size and charge differences. Available in horizontal (submarine) formats for agarose gel electrophoresis of DNA/RNA and some proteins, and vertical formats for polyacrylamide gel electrophoresis (PAGE) of proteins. Constructed of polycarbonate or acrylic tanks with platinum or carbon electrodes, safety-interlocked lids, and buffer reservoirs (200-2,000 mL). Designed for use with external power supplies (100-500 V). Primary clinical applications include serum protein electrophoresis (SPEP) for diagnosis of multiple myeloma and monoclonal gammopathies, hemoglobin electrophoresis for sickle cell disease and thalassemias, urine protein electrophoresis for Bence Jones proteins, immunofixation electrophoresis (IFE) for monoclonal protein characterization, isoenzyme analysis (CK-MB, LDH) for myocardial infarction and liver disease, and DNA/RNA electrophoresis for molecular diagnostics. Essential equipment in clinical pathology, hematology, molecular diagnostics, and research laboratories requiring separation and analysis of proteins and nucleic acids for diagnostic and research purposes.