Hematology Analyzer

Name: Hematology Analyzer - Amaris Medical Solutions
Price: 1.00 USD
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A Hematology Analyzer is a compact, automated benchtop analyzer designed to perform Complete Blood Counts (CBC) with a 3-part white blood cell differential. Utilizing impedance and photometric methods, it delivers rapid, precise results for red blood cells, white blood cells, platelets, and key indices from a small blood sample. Ideal for physician offices, small clinics, and satellite laboratories, it enables in-house hematology testing with walk-away operation. Its automated flagging system highlights abnormal results that require further manual smear review. As a core instrument for initial hematological screening, it combines efficiency with essential diagnostic capability for routine patient management.

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Categories: LABORATORY EQUIPMENT AND SUPPLIES, Analyzers Tags: BloodAnalyzer, CBCAnalyzer, ClinicalLaboratory, DiagnosticInstrument, HematologyAnalyzer, MedicalAnalyzer

Description

Hematology Analyzer

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Complete Blood Count (CBC) Analysis:

Primary Use: The primary and core function is to perform an automated, high-precision CBC, which is the most frequently ordered clinical laboratory test. It quantitatively measures the cellular components of blood: Red Blood Cells (RBCs), White Blood Cells (WBCs), and Platelets (PLTs).
How it helps: Transforms a single blood sample into a comprehensive picture of a patient’s health, providing doctors with essential information about oxygen-carrying capacity, immune system function, and clotting ability in minutes.

2. Diagnosis & Monitoring of Hematological Disorders:

Primary Use: Essential for diagnosing and managing conditions such as anemias (via RBC indices like MCV, MCH, MCHC), leukemias and infections (via WBC differential count), and thrombocytopenias/thrombocytoses (via platelet count).
How it helps: Gives hematologists and oncologists the detailed information they need to diagnose blood disorders accurately and track how well treatments are working, from chemotherapy to iron supplementation.

3. General Health Screening & Pre-operative Testing:

Primary Use: A fundamental component of routine health check-ups, annual physicals, and mandatory pre-surgical assessments to screen for hidden conditions and establish a patient’s baseline.
How it helps: Uncovers silent health problems before they cause symptoms, allowing for early intervention and ensuring surgical patients are healthy enough to undergo procedures safely.

4. Therapy Monitoring:

Primary Use: Used to monitor patient response to treatments such as chemotherapy (tracking bone marrow suppression via WBC/PLT counts), antibiotic therapy for infections (tracking WBC count), and nutritional therapy for anemias.
How it helps: Provides oncologists with critical information about how chemotherapy is affecting a patient’s bone marrow, allowing them to adjust treatment to maximize effectiveness while minimizing dangerous side effects.

5. Detection of Systemic Disease Indicators:

Primary Use: Abnormal CBC results can serve as the first indicator of systemic diseases ranging from chronic inflammation and autoimmune disorders to malignancies and bone marrow failure.
How it helps: Acts as an early warning system for a wide range of serious conditions, often providing the first clue that something is wrong and guiding further diagnostic testing.

SECONDARY & SUPPORTIVE USES

1. Blood Bank Donor Screening: Used to ensure donors meet minimum hemoglobin/hematocrit requirements and to screen for potential blood cell abnormalities, protecting both donors and recipients.

2. Point-of-Care Testing (POCT): In models designed for smaller clinics, urgent care centers, or physician office laboratories (POLs), it provides rapid in-house results, reducing turnaround time and enabling immediate clinical decisions.

3. Veterinary Medicine: Similar analyzers are used in veterinary clinics for animal CBCs, helping veterinarians diagnose and treat illnesses in pets and livestock with the same accuracy as human medicine.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: Automated, bench-top Hematology Analyzer.
Methodology: Likely utilizes a combination of Electrical Impedance (Coulter Principle) for cell counting and sizing, and Colorimetric (Hemoglobincyanide or SLS-Hemoglobin) method for hemoglobin measurement.
Throughput: Designed for small to medium workload, suitable for clinics, small hospitals, and group practices. Typical throughput of 40-60 samples per hour.

2. TECHNICAL & PERFORMANCE PROPERTIES

Reportable Parameters (Typical for 3-Diff):
- RBC Parameters: RBC Count, Hemoglobin (HGB), Hematocrit (HCT), MCV, MCH, MCHC, RDW.
- WBC Parameters: Total WBC Count, Three-Part Differential (Granulocytes, Lymphocytes, Mixed Cells/Monocytes).
- PLT Parameters: Platelet Count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW).
Sample Type & Volume: Uses EDTA-anticoagulated whole blood. Sample volume is small (typically 20-40 µL for capillary or 100-150 µL for venous blood).
Calibration & Quality Control: Requires calibration with manufacturer-provided calibrators. Must run daily internal quality control (QC) materials (normal, abnormal) to verify accuracy and precision. Likely compatible with external QC programs.
Flagging System: Includes an automated flagging system to alert the operator to abnormal cell populations, suspect results, or the need for a manual blood smear review (e.g., for atypical lymphocytes, blasts, platelet clumps).

3. PHYSICAL & OPERATIONAL PROPERTIES

Form Factor: Compact, benchtop unit with an integrated touchscreen or button interface.
Consumables: Uses dedicated reagents (diluent, lyse, cleaner, hemolyzer) and disposable components (sampling tips, cuvettes, waste containers).
Connectivity: Includes ports (USB, RS-232) or network capability for connection to a Laboratory Information System (LIS) for bidirectional data transfer.
Operation: Features walk-away operation after sample loading. Includes automatic cleaning cycles and self-diagnostics.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Approvals: Must have CE Marking (for EU market) and/or local regulatory approvals. May have FDA 510(k) clearance if marketed in the USA.
Quality Standards: Manufactured under a ISO 13485 quality management system.
Safety Standards: Complies with IEC 61010-1 (Safety requirements for electrical equipment for measurement, control, and laboratory use) and relevant laboratory safety standards for biological hazards (sample handling).
Waste Handling: Manages biohazardous liquid waste (blood, reagents) internally into a closed waste container, minimizing operator exposure.

5. STORAGE & HANDLING ATTRIBUTES

Storage Conditions: Store the analyzer in a clean, temperature-controlled laboratory environment (typically 15-30°C). Protect from dust, moisture, and direct sunlight.
Reagent Storage: Reagents must be stored as per manufacturer instructions (often at 2-8°C or room temperature). Check expiry dates.
Routine Maintenance: Requires daily, weekly, and monthly maintenance as per the operator's manual (e.g., cleaning probes, replacing filters, running cleaning cycles, emptying waste) to ensure reliability and longevity.
Calibration Schedule: Calibrate with new lots of reagents, after major maintenance, or as indicated by QC failures.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Automation of the CBC, providing rapid, reproducible, and precise quantitative data that forms the foundation of hematological diagnosis.
Limitation: As a 3-part differential analyzer, it has limitations in identifying specific WBC subtypes (e.g., cannot separate monocytes from eosinophils/basophils). Any flagged or abnormal result requires confirmation by a manual microscopic review of a peripheral blood smear by a trained technologist or pathologist.

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Biosafety: Treat all patient samples as potentially infectious. Wear appropriate PPE (lab coat, gloves, safety glasses) when handling samples, reagents, or waste.
Chemical Safety: Reagents may contain hazardous chemicals (e.g., cyanide in some hemoglobin lyse). Handle with care, avoid ingestion or skin/eye contact. Use in a well-ventilated area.
Electrical Safety: Use the provided power cord. Do not operate with a damaged cord or in a wet environment.
Sharp Objects: Exercise caution with sample probes and capillary tubes to avoid needlestick injuries.

2. FIRST AID MEASURES

Sample/Reagent Contact: If blood or reagents contact skin, wash immediately with soap and water. If in eyes, rinse thoroughly with water for 15 minutes and seek medical attention.
Electrical Shock: Disconnect power. If injury occurs, provide first aid and seek medical attention.
Chemical Ingestion: If reagents are ingested, do NOT induce vomiting. Seek immediate medical attention and provide the reagent Safety Data Sheet (SDS).

3. FIRE FIGHTING MEASURES

Flammability: Internal plastics, electronics, and some reagents are combustible.
Extinguishing Media: For electrical fires, use a CO₂ or dry chemical (Class C) fire extinguisher. Do not use water.
Firefighter Instructions: Evacuate area. Firefighters should use full protective gear and SCBA due to potential toxic fumes from burning electronics and chemicals.

Hematology Analyzer

Hematology Analyzer

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Complete Blood Count (CBC) Analysis:

Primary Use: The primary and core function is to perform an automated, high-precision CBC, which is the most frequently ordered clinical laboratory test. It quantitatively measures the cellular components of blood: Red Blood Cells (RBCs), White Blood Cells (WBCs), and Platelets (PLTs).

How it helps: Transforms a single blood sample into a comprehensive picture of a patient’s health, providing doctors with essential information about oxygen-carrying capacity, immune system function, and clotting ability in minutes.

2. Diagnosis & Monitoring of Hematological Disorders:

Primary Use: Essential for diagnosing and managing conditions such as anemias (via RBC indices like MCV, MCH, MCHC), leukemias and infections (via WBC differential count), and thrombocytopenias/thrombocytoses (via platelet count).

How it helps: Gives hematologists and oncologists the detailed information they need to diagnose blood disorders accurately and track how well treatments are working, from chemotherapy to iron supplementation.

3. General Health Screening & Pre-operative Testing:

Primary Use: A fundamental component of routine health check-ups, annual physicals, and mandatory pre-surgical assessments to screen for hidden conditions and establish a patient’s baseline.

How it helps: Uncovers silent health problems before they cause symptoms, allowing for early intervention and ensuring surgical patients are healthy enough to undergo procedures safely.

4. Therapy Monitoring:

Primary Use: Used to monitor patient response to treatments such as chemotherapy (tracking bone marrow suppression via WBC/PLT counts), antibiotic therapy for infections (tracking WBC count), and nutritional therapy for anemias.

How it helps: Provides oncologists with critical information about how chemotherapy is affecting a patient’s bone marrow, allowing them to adjust treatment to maximize effectiveness while minimizing dangerous side effects.

5. Detection of Systemic Disease Indicators:

Primary Use: Abnormal CBC results can serve as the first indicator of systemic diseases ranging from chronic inflammation and autoimmune disorders to malignancies and bone marrow failure.

How it helps: Acts as an early warning system for a wide range of serious conditions, often providing the first clue that something is wrong and guiding further diagnostic testing.

SECONDARY & SUPPORTIVE USES

1. Blood Bank Donor Screening: Used to ensure donors meet minimum hemoglobin/hematocrit requirements and to screen for potential blood cell abnormalities, protecting both donors and recipients.

2. Point-of-Care Testing (POCT): In models designed for smaller clinics, urgent care centers, or physician office laboratories (POLs), it provides rapid in-house results, reducing turnaround time and enabling immediate clinical decisions.

3. Veterinary Medicine: Similar analyzers are used in veterinary clinics for animal CBCs, helping veterinarians diagnose and treat illnesses in pets and livestock with the same accuracy as human medicine.

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: Automated, bench-top Hematology Analyzer.

Methodology: Likely utilizes a combination of Electrical Impedance (Coulter Principle) for cell counting and sizing, and Colorimetric (Hemoglobincyanide or SLS-Hemoglobin) method for hemoglobin measurement.

Throughput: Designed for small to medium workload, suitable for clinics, small hospitals, and group practices. Typical throughput of 40-60 samples per hour.

2. TECHNICAL & PERFORMANCE PROPERTIES

Reportable Parameters (Typical for 3-Diff):

RBC Parameters: RBC Count, Hemoglobin (HGB), Hematocrit (HCT), MCV, MCH, MCHC, RDW.

WBC Parameters: Total WBC Count, Three-Part Differential (Granulocytes, Lymphocytes, Mixed Cells/Monocytes).

PLT Parameters: Platelet Count, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW).

Sample Type & Volume: Uses EDTA-anticoagulated whole blood. Sample volume is small (typically 20-40 µL for capillary or 100-150 µL for venous blood).

Calibration & Quality Control: Requires calibration with manufacturer-provided calibrators. Must run daily internal quality control (QC) materials (normal, abnormal) to verify accuracy and precision. Likely compatible with external QC programs.

Flagging System: Includes an automated flagging system to alert the operator to abnormal cell populations, suspect results, or the need for a manual blood smear review (e.g., for atypical lymphocytes, blasts, platelet clumps).

3. PHYSICAL & OPERATIONAL PROPERTIES

Form Factor: Compact, benchtop unit with an integrated touchscreen or button interface.

Consumables: Uses dedicated reagents (diluent, lyse, cleaner, hemolyzer) and disposable components (sampling tips, cuvettes, waste containers).

Connectivity: Includes ports (USB, RS-232) or network capability for connection to a Laboratory Information System (LIS) for bidirectional data transfer.

Operation: Features walk-away operation after sample loading. Includes automatic cleaning cycles and self-diagnostics.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Approvals: Must have CE Marking (for EU market) and/or local regulatory approvals. May have FDA 510(k) clearance if marketed in the USA.

Quality Standards: Manufactured under a ISO 13485 quality management system.

Safety Standards: Complies with IEC 61010-1 (Safety requirements for electrical equipment for measurement, control, and laboratory use) and relevant laboratory safety standards for biological hazards (sample handling).

Waste Handling: Manages biohazardous liquid waste (blood, reagents) internally into a closed waste container, minimizing operator exposure.

5. STORAGE & HANDLING ATTRIBUTES

Storage Conditions: Store the analyzer in a clean, temperature-controlled laboratory environment (typically 15-30°C). Protect from dust, moisture, and direct sunlight.

Reagent Storage: Reagents must be stored as per manufacturer instructions (often at 2-8°C or room temperature). Check expiry dates.

Routine Maintenance: Requires daily, weekly, and monthly maintenance as per the operator's manual (e.g., cleaning probes, replacing filters, running cleaning cycles, emptying waste) to ensure reliability and longevity.

Calibration Schedule: Calibrate with new lots of reagents, after major maintenance, or as indicated by QC failures.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Automation of the CBC, providing rapid, reproducible, and precise quantitative data that forms the foundation of hematological diagnosis.

1. SAFETY PRECAUTIONS

Biosafety: Treat all patient samples as potentially infectious. Wear appropriate PPE (lab coat, gloves, safety glasses) when handling samples, reagents, or waste.

Chemical Safety: Reagents may contain hazardous chemicals (e.g., cyanide in some hemoglobin lyse). Handle with care, avoid ingestion or skin/eye contact. Use in a well-ventilated area.

Electrical Safety: Use the provided power cord. Do not operate with a damaged cord or in a wet environment.

Sharp Objects: Exercise caution with sample probes and capillary tubes to avoid needlestick injuries.

2. FIRST AID MEASURES

Sample/Reagent Contact: If blood or reagents contact skin, wash immediately with soap and water. If in eyes, rinse thoroughly with water for 15 minutes and seek medical attention.

Electrical Shock: Disconnect power. If injury occurs, provide first aid and seek medical attention.

Chemical Ingestion: If reagents are ingested, do NOT induce vomiting. Seek immediate medical attention and provide the reagent Safety Data Sheet (SDS).

3. FIRE FIGHTING MEASURES

Flammability: Internal plastics, electronics, and some reagents are combustible.

Extinguishing Media: For electrical fires, use a CO₂ or dry chemical (Class C) fire extinguisher. Do not use water.

Firefighter Instructions: Evacuate area. Firefighters should use full protective gear and SCBA due to potential toxic fumes from burning electronics and chemicals.

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