An Infant T-piece Resuscitator is a Class II medical device designed for neonatal resuscitation and controlled positive pressure ventilation, delivering precise, consistent peak inspiratory pressures (PIP) and positive end-expiratory pressure (PEEP) as recommended by Neonatal Resuscitation Program (NRP) guidelines. The T-piece assembly connects to compressed air/oxygen source (5-15 L/min) with adjustable PIP (10-40 cmHâ‚‚O) and PEEP (0-10 cmHâ‚‚O) controls, built-in pressure manometer, and pressure relief valve (30-40 cmHâ‚‚O). Operator occludes port to deliver breaths (typically 40-60/min), with consistent pressures maintained regardless of technique. Essential advantages over bag-valve-mask devices include operator-independent pressure delivery, ability to provide PEEP (critical for preterm lung protection), reduced risk of barotrauma, and hands-free PEEP allowing two-handed mask seal. Primary clinical applications include delivery room resuscitation, stabilization of extremely preterm infants (<1,000 g), CPAP/PEEP delivery, meconium aspiration management, and neonatal transport ventilation. Critical safety considerations include verifying gas supply (5-15 L/min), monitoring manometer pressures, ensuring proper mask seal, observing chest rise, and titrating FiO2 to SpO2 targets. Indispensable resuscitation equipment in every delivery room, NICU, and neonatal transport setting worldwide.