Enzyme Reaction

The Pro Thermo Control (HC110) is a programmable digital dry bath with both heating and cooling capabilities, designed for precise temperature-controlled sample preparation in clinical diagnostic, molecular biology, and research laboratories . With a temperature range from -5°C to 110°C (heating to 110°C, cooling to 25°C below room temperature) and temperature control accuracy of ±0.5°C, this compact benchtop unit provides consistent, uniform heating and cooling for a wide range of diagnostic and research applications .

The HC110-Pro features a microprocessor-controlled system with TFT display for real-time temperature and time monitoring, programmable memory supporting up to 9 custom temperature control programs, and rapid heating (5.5°C/min) and controlled cooling (2.5°C/min from 100°C to room temperature) capabilities . The magnetic adsorption technology allows tool-free, secure mounting of interchangeable aluminum heating blocks compatible with various tube formats including 0.2mL PCR tubes, 0.5mL, 1.5mL, 2mL, 5mL, 15mL, 50mL centrifuge tubes, and microplates . The included block lid provides heat preservation, temperature stability, and contamination prevention .

For the clinical laboratory scientist and molecular biologist, the HC110-Pro supports DNA denaturation for PCR preparation and nucleic acid amplification, enzyme-substrate reactions for biochemical tests and clinical chemistry, serum inactivation for immunoassays and serological testing, protein denaturation for Western blotting and purification, and restriction enzyme heat inactivation . The active cooling capability enables rapid cooling of samples after high-temperature processing, preserving heat-sensitive DNA, RNA, enzymes, and proteins for downstream molecular diagnostic workflows .

Safety features include over-temperature protection (150°C safety cut-off) , built-in temperature calibration function for long-term accuracy , and magnetic block recognition . For the patient undergoing diagnostic testing for infectious diseases, genetic conditions, or oncology biomarkers, the HC110-Pro's precise temperature control (±0.5°C accuracy) and combined heating/cooling capability ensure reliable enzyme reaction conditions, consistent DNA denaturation, and accurate sample preparation—supporting reliable test results that guide appropriate treatment decisions across clinical chemistry, molecular diagnostics, and research applications .