FISH Microscope

A Fluorescent Microscope is a specialized Class I medical device designed for visualizing specimens labeled with fluorescent dyes (fluorochromes) that emit light at specific wavelengths when excited by high-intensity illumination. Equipped with high-pressure mercury (HBO), xenon (XBO), metal halide, or LED light sources, interchangeable filter cubes for specific fluorochromes (DAPI, FITC, TRITC, Cy3, Cy5), and high numerical aperture objectives for maximum light collection. Features include epifluorescence design, precision filter turret (4-6 positions), UV-blocking safety shields, and trinocular head for digital imaging. Primary clinical applications include immunofluorescence for autoimmune disease diagnosis (ANA, ANCA, anti-dsDNA, skin/kidney biopsies), fluorescence in situ hybridization (FISH) for genetic abnormalities (aneuploidy, deletions, translocations, HER2 amplification), auramine-rhodamine staining for tuberculosis screening, direct fluorescent antibody (DFA) testing for Legionella, Pneumocystis, Cryptosporidium, Giardia, and respiratory viruses, and FTA-ABS confirmatory testing for syphilis. Essential equipment in immunology, microbiology, pathology, cytogenetics, and molecular diagnostics laboratories requiring sensitive and specific detection of fluorescent signals for diagnosis of infectious, autoimmune, genetic, and neoplastic diseases.