Electronic Bottle-Top Dispenser (dFlow)

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The dFlow Electronic Bottle-Top Dispenser is a motor-controlled digital dispensing system designed for precise, fatigue-free delivery of laboratory reagents directly from reagent bottles . Featuring a volume range of 0.1-99.9mL with 100μL resolution, 16 adjustable speed levels, and a TFT display module, this dispenser provides accurate volume delivery (10mL: R=0.5%, CV=0.3%) compliant with DIN EN ISO 8655 standards .
The external remote control panel allows operation without manual disturbance, significantly reducing the risk of repetitive strain injury while keeping operators away from hazardous chemical contact . Two operation modes—dispenser mode for single aliquots and stepper mode for continuous multi-volume dispensing—provide versatility for diverse laboratory workflows . A recirculation feature minimizes costly reagent waste by allowing priming without discarding expensive solutions .
For the clinical laboratory scientist and medical technologist, the dFlow electronic dispenser supports accurate dispensing of clinical chemistry reagents, immunoassay buffers, molecular biology reagents, and pharmaceutical quality control samples. The stepper motor drive ensures smooth, consistent operation across 16 adjustable speed levels, accommodating liquids of varying viscosities . The fluid path features chemically resistant materials (borosilicate glass cylinder, FEP tubing, PTFE components) compatible with a wide range of laboratory reagents . Included bottle adapters (S40, GL25, GL28, GL32, GL38) allow attachment to various reagent bottle thread sizes via the standard GL45 base .
For the patient undergoing diagnostic testing, precise and consistent reagent dispensing using the dFlow electronic bottle-top dispenser ensures that clinical chemistry, immunoassay, and molecular diagnostic test results are accurate, reliable, and reproducible—supporting appropriate clinical decision-making across laboratory medicine and pharmaceutical quality control applications.
Description

Electronic Bottle-Top Dispenser (dFlow) 

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Precision Dispensing of Clinical Laboratory Reagents
  • Primary Use: Provides a motor-controlled electronic bottle-top dispenser with a volume range of 0.1-99.9mL, 16 adjustable speed levels, and a TFT display module, designed for accurate, fatigue-free dispensing of reagents, buffers, and chemical solutions directly from laboratory reagent bottles .
  • How it helps: For the clinical laboratory scientist and medical technologist, the dFlow electronic dispenser eliminates manual pipetting fatigue by using a high-quality stepper motor that provides smooth, consistent dispensing with precision accuracy (10mL: R=0.5%, CV=0.3%) . The external remote control panel allows operation without manual disturbance, reducing the risk of repetitive strain injury . For the patient, precise reagent dispensing ensures that diagnostic test results are accurate and reproducible, reducing the risk of analytical errors that could lead to misdiagnosis or incorrect treatment decisions.
2. Two Operating Modes for Versatile Laboratory Workflows
  • Primary Use: Features two operation modes – dispenser mode (single-volume dispensing) and stepper mode (continuous multi-volume dispensing) – allowing users to select the appropriate mode for different laboratory applications .
  • How it helps: For the clinical laboratory scientist and research technician, dispenser mode is ideal for routine aliquot preparation where consistent single volumes are required, while stepper mode allows programming of multiple dispenses of the same volume sequentially, significantly improving workflow efficiency for high-throughput tasks . The TFT display provides clear visualization of volume settings and mode selection . For the patient, efficient laboratory workflows reduce turnaround times for diagnostic test results, enabling earlier clinical intervention.
3. Recirculation Feature to Minimize Reagent Waste
  • Primary Use: Incorporates a reagent recovery feature (recirculation mode) that allows unused reagent to be returned to the bottle, minimizing costly reagent waste and reducing environmental impact .
  • How it helps: For the laboratory manager and quality control officer, the recirculation feature allows priming of the dispensing tube without discarding expensive reagents into waste containers—particularly valuable for costly diagnostic reagents, antibodies, and pharmaceutical preparations. For the patient, efficient reagent use helps control laboratory operating costs, which can contribute to more affordable diagnostic testing.
4. Adjustable Aspiration and Dispensing Speed
  • Primary Use: Allows independent adjustment of aspiration and dispensing speeds across 16 levels, enabling optimization for different liquid viscosities and volumes .
  • How it helps: For the clinical laboratory scientist handling diverse reagent types, the variable speed control accommodates both low-viscosity liquids (e.g., water-based buffers) and high-viscosity liquids (e.g., glycerol, protein solutions, concentrated reagents). This prevents issues such as splashing, foaming, or incomplete aspiration that could affect volume accuracy. For the patient, proper handling of diagnostic reagents ensures that test results are not compromised by pre-analytical variables.
5. Stepper Motor for Smooth, Accurate Dispensing
  • Primary Use: Utilizes a high-quality stepper motor drive system that provides smooth, vibration-free operation and precise volume control with a resolution of 100μL .
  • How it helps: For the clinical laboratory scientist, the stepper motor eliminates the variability associated with manual pipetting, ensuring consistent volume delivery across hundreds of dispenses. The motor-driven operation reduces physical fatigue during repetitive dispensing tasks. For the patient, consistent volume accuracy ensures that diagnostic test results are reliable and reproducible, supporting accurate clinical decision-making.

SECONDARY & SUPPORTIVE USES

1. Clinical Chemistry Reagent Dispensing: Used for accurate dispensing of clinical chemistry reagents, calibrators, and controls into reaction cuvettes or sample tubes .
2. Immunoassay Buffer and Wash Solution Dispensing: Provides precise volume delivery of wash buffers, blocking solutions, and substrate solutions for ELISA and other immunoassay platforms.
3. Molecular Biology Reagent Preparation: Used for dispensing PCR master mixes, buffers, enzymes, and nucleotide solutions in molecular diagnostics workflows.
4. Pharmaceutical Quality Control Sample Preparation: Dispenses dissolution media, buffer solutions, and quality control samples for pharmaceutical testing .
5. Histology and Pathology Staining Solution Dispensing: Used to dispense hematoxylin, eosin, and other histological stains for tissue processing and slide preparation.
6. Blood Bank Reagent Dispensing: Provides accurate dispensing of antisera, reagent red blood cells, and other blood bank reagents for compatibility testing.
7. Microbiology Culture Media Preparation: Dispenses sterile culture media, broth, and additives into culture tubes, plates, and bottles.
8. Hematology Reagent Dispensing: Used for dispensing staining solutions, lysing reagents, and diluents for complete blood count (CBC) and differential analysis.
9. Urinalysis Reagent Dispensing: Dispenses urine chemistry strips reagents, sediment stains, and质量控制 materials for urinalysis workflows.
10. Coagulation Reagent Preparation: Provides accurate dispensing of thromboplastin, calcium chloride, and other coagulation study reagents.
11. Drug Discovery and High-Throughput Screening: Used for dispensing assay components into microplates for drug discovery and compound screening applications.
12. Analytical Chemistry Standard Preparation: Dispenses volumetric standards, calibration solutions, and quality control materials for HPLC, GC, and other analytical instrumentation.
13. Toxicology Sample Preparation: Used for dispensing extraction solvents, internal standards, and derivatization reagents for toxicology screening.
14. Research and Academic Laboratories: Provides general-purpose reagent dispensing for diverse laboratory applications in research and teaching laboratories.
15. Veterinary Diagnostic Laboratory Reagent Dispensing: Dispenses diagnostic reagents for animal health testing and infectious disease diagnosis.
16. Food Safety and Environmental Testing: Used for dispensing extraction solvents, buffers, and reagents for food and water quality testing.
17. Adhesive and Sealant Dispensing: Dispenses medical adhesives, dental materials, and laboratory sealants requiring precise volume control.
18. Custom Reagent Formulation: Used for preparing custom reagent blends, cocktails, and master mixes with multiple components.
19. Laboratory Automation Integration: Compatible with semi-automated and automated laboratory workflows requiring reliable reagent dispensing.
20. Bioprocess Buffer Preparation: Dispenses buffers and media components for bioprocessing and cell culture applications.
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: An electronic, motor-controlled bottle-top dispenser with digital control, TFT display, and external remote panel, designed for precise, fatigue-free dispensing of laboratory reagents directly from reagent bottles .
  • Designation: dFlow Electronic Bottle-Top Dispenser, Electronic Bottle Top Dispenser, dFlow Digital Dispenser, Motorized Bottle-Top Dispenser, DLAB dFlow .
  • Key Components:
o Dispensing Head: Motor-driven piston assembly with borosilicate glass cylinder and FEP fluid path .
o External Control Panel: Remote TFT display unit for volume selection, mode selection, and operation control .
o Aspiration Tube: FEP tubing for chemical-resistant liquid aspiration from reagent bottle .
o Dispensing Nozzle: Adjustable dispensing tip with two included nozzle options .
o Bottle Adapters: Set of 5 adapters (S40, GL25, GL28, GL32, GL38) for compatibility with various reagent bottle thread sizes .
o Stepper Motor: High-quality stepper motor drive for smooth, accurate dispensing .
o GL45 Thread Base: Standard GL45 thread for direct attachment to reagent bottles .
o Recirculation Valve: Allows reagent recovery to minimize waste .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Volume Range: 0.1-99.9mL; maximum piston lift is 10mL; resolution is 100μL .
  • Volume Accuracy (Dispenser Mode): 10mL: R=0.5% (±30μL), CV=0.3% (±10μL); 5mL: R=1.0%, CV=0.6%; 1mL: R=5.0%, CV=3.0% .
  • Volume Accuracy (Stepper Mode): 1mL: R=±6μL, CV=±9μL .
  • Dispensing Speed: 16 adjustable speed levels .
  • Aspiration Speed: 16 adjustable speed levels .
  • Operating Temperature Range: 10-30°C (15-40°C depending on source) .
  • Operation Modes: Dispenser mode (single-volume) and Stepper mode (continuous multi-volume) .
  • Control Type: External remote control panel .
  • Display: TFT display module for simple volume selection and control .
  • Quality Control Standards: DIN EN ISO 8655 compliant .
  • Wetted Materials: Borosilicate glass (cylinder), FEP (aspiration/discharge tubing), PTFE, PP .
  • Bottle Thread Compatibility: GL45 standard; includes adapters for S40, GL25, GL28, GL32, GL38 .
  • Power Supply: External AC adapter (included) .
  • Aspiration Time (25mL pure water): <8 seconds .
  • Dimensions (Package): 260 × 360 × 240 mm, 1.52 kg .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Construction: Electronic drive unit with remote control panel; chemically resistant fluid path (borosilicate glass, FEP, PTFE) .
  • Display: TFT screen showing volume setting, mode selection, and operation status .
  • Operation Modes: Dispenser mode (single aliquot dispensing) and Stepper mode (multiple sequential dispenses) .
  • Control: External remote panel allows operation without manual disturbance to the dispenser .
  • Recirculation Feature: Allows reagent recovery to minimize waste during priming and purging .
  • Speed Adjustment: 16-level speed control for both aspiration and dispensing .
  • Power Connection: External AC adapter; unit is electrically powered, not battery-operated.
  • Maintenance: Easy disassembly for cleaning; fluid path components are chemically resistant; autoclaving of certain components may be possible (verify per manufacturer).
  • Compatibility: Designed for use with standard laboratory reagent bottles; bottle not included .

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Laboratory equipment for in vitro diagnostic use; quality controlled according to DIN EN ISO 8655 .
  • Safety Features: External control reduces manual handling of hazardous chemicals; motor operation eliminates repetitive strain injury risk .
  • Chemical Resistance: Fluid path components (borosilicate glass, FEP, PTFE) resist a wide range of laboratory chemicals, acids, bases, and organic solvents .
  • Electrical Safety: Operates on low voltage via external AC adapter; CE certified per manufacturer.
  • Ergonomic Design: Motorized operation eliminates manual pipetting fatigue, reducing the risk of repetitive strain injury during high-volume dispensing .
  • Indicators: TFT display provides clear visual feedback of selected volume and operation mode.

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store the dispenser in a clean, dry location when not in use; protect from dust and chemical vapors.
  • Cleaning: Rinse fluid path with appropriate solvent after each use; for thorough cleaning, disassemble as per manufacturer instructions; clean external surfaces with damp cloth.
  • Inspection: Inspect cylinder, piston, and tubing for damage or wear before each use; check O-rings for integrity.
  • Operation: Attach appropriate bottle adapter to reagent bottle; secure dispenser to bottle via GL45 thread; prime the system by aspirating and dispensing several times to remove air bubbles; select desired volume and mode via TFT display; press dispense button.
  • Mode Selection: Use dispenser mode for single aliquots; use stepper mode for multiple sequential dispenses of the same volume.
  • Speed Adjustment: Adjust aspiration and dispensing speeds based on liquid viscosity (lower speeds for viscous liquids, higher speeds for low-viscosity liquids).
  • Recirculation Use: Use recirculation feature to prime system without wasting reagent; excess reagent can be returned to bottle.
  • Bottle Compatibility: Use appropriate bottle adapter for the reagent bottle thread size; ensure tight seal to prevent leakage.
  • Spill Management: If liquid spills onto unit, disconnect power immediately, clean thoroughly, allow to dry before reuse.
  • Maintenance: Periodic calibration verification using gravimetric method per ISO 8655 recommended.

6. LABORATORY & CLINICAL APPLICATIONS

  • Primary Application: Precise, motor-controlled dispensing of clinical chemistry reagents, immunoassay buffers, molecular biology reagents, pharmaceutical preparations, and chemical solutions in clinical diagnostic, pharmaceutical, and research laboratories.
  • Clinical Role: Essential liquid handling equipment in clinical chemistry laboratories, immunology laboratories, molecular diagnostics labs, pharmaceutical quality control, histology and pathology laboratories, blood banks, and research facilities requiring accurate, fatigue-free reagent dispensing.
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Chemical Compatibility: Verify compatibility of all wetted materials (borosilicate glass, FEP, PTFE) with the reagents being dispensed before use.
  • Electrical Safety: Keep the external control panel and AC adapter away from liquids; disconnect power before cleaning or maintenance.
  • Ergonomic Use: Use the external remote control to minimize manual handling of hazardous chemicals; the motorized operation reduces repetitive strain injury risk .
  • Proper Priming: Always prime the system by aspirating and dispensing several times before beginning accurate dispensing to ensure the fluid path is filled and air bubbles are removed.
  • Volume Verification: Periodically verify dispensed volume gravimetrically to ensure accuracy, especially after changing reagents or speed settings.
  • Tube Positioning: Ensure the dispensing nozzle is positioned correctly over the receiving vessel to avoid splashing or spillage.
  • Bottle Stability: Ensure the reagent bottle is stable and securely positioned to prevent tipping during operation.
  • Disposal: Dispose of used reagents and chemical waste according to local environmental regulations.
  • Training: Only trained laboratory personnel should operate the dFlow Electronic Bottle-Top Dispenser for clinical diagnostic applications.

2. FIRST AID MEASURES

  • Chemical Splash: If reagent splashes onto skin, wash immediately with soap and water; if in eyes, flush with water for 15 minutes, seek medical attention; refer to reagent Safety Data Sheet (SDS) for specific guidance.
  • Electrical Malfunction: If unit shows signs of electrical malfunction (smoke, burning smell), disconnect power immediately; do not attempt to operate; contact service personnel.
  • Mechanical Failure: If dispenser fails to aspirate or dispense properly, check for air leaks, debris in valve, or component damage; contact service if issue persists.
  • Chemical Spill: If large chemical spill occurs, evacuate area, follow facility chemical spill protocol, and use appropriate PPE for cleanup.

3. FIRE FIGHTING MEASURES

  • Flammability: Plastic components (control panel housing, adapters) are combustible; electrical components present fire risk.
  • Extinguishing Media: Use carbon dioxide (CO₂) or dry chemical extinguisher for electrical fires.
  • Fire Response: Unplug unit immediately; do not use water on electrical fire; refer to reagent SDS for flammability of dispensed liquids.