Floor Type Low Speed Cooling Centrifuge

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A Floor Type Low Speed Cooling Centrifuge is a heavy-duty, floor-standing refrigerated centrifuge designed for large-scale, temperature-controlled processing of biological samples in clinical laboratories, blood banks, biopharmaceutical manufacturing, and research facilities. With capacities up to 12 blood bags, 6 × 1 L bottles, 192 blood collection tubes, or 20 microplates per run, these units operate at 4,000-8,000 RPM generating RCF up to 12,000 x g with precise temperature control from -10°C to +40°C (±1°C). Features include high-torque brushless motors, advanced refrigeration systems, color touchscreen interfaces, programmable protocols (50-100 programs), multiple acceleration/deceleration profiles, comprehensive imbalance detection, aerosol-tight rotors, and GMP-compliant data logging options. Primary clinical applications include blood bank processing (packed cells, plasma, cryoprecipitate), coagulation studies requiring cold centrifugation, temperature-sensitive molecular biology preparations, vaccine and biopharmaceutical production, cold precipitation studies, and long-duration centrifugation protocols. Essential equipment for high-volume clinical laboratories, blood donor centers, and GMP manufacturing facilities requiring precise temperature control and large sample capacity with reproducible, validated results.

Categories: LABORATORY EQUIPMENT AND SUPPLIES, Centrifuges and Separators, Lab Consumables, Refrigerators, Freezers, and Storage Units Tags: Bio pharmaceutical Centrifuge, Blood Bank Centrifuge, Cold Centrifuge, Floor Type Centrifuge, GMP Centrifuge, Large Capacity Refrigerated Centrifuge, Low Speed Cooling Centrifuge, Refrigerated Floor Centrifuge

Description

Floor Type Low Speed Cooling Centrifuge

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Large-Volume Blood Separation with Temperature Control:

Primary Use: Floor-standing cooling centrifuges process hundreds of blood samples simultaneously for serum or plasma separation while maintaining precise temperatures (typically 4°C) to preserve labile components such as coagulation factors, complement proteins, and enzymes for accurate clinical chemistry and coagulation testing.
How it helps: Ensures that delicate blood components remain stable during processing, giving laboratory professionals and clinicians confidence that test results accurately reflect patient health rather than degradation during handling.

2. Blood Bank and Transfusion Service Processing:

Primary Use: Essential for preparing packed red blood cells, platelet concentrates, fresh frozen plasma, and cryoprecipitate from donated blood units, with refrigeration ensuring optimal preservation of blood components during processing.
How it helps: Makes the most of every blood donation by carefully separating whole blood into components that can help multiple patients, while refrigeration preserves these life-saving products until they are needed.

3. Cold Centrifugation for Coagulation Studies:

Primary Use: Maintains samples at 4°C during centrifugation to preserve coagulation factors (Factor V, VIII) and prevent cold activation of platelets, ensuring accurate PT, APTT, and factor assay results.
How it helps: Provides hematologists and coagulation specialists with reliable test results, ensuring that patients with bleeding disorders receive accurate diagnoses and appropriate treatment based on properly preserved samples.

4. Temperature-Sensitive Molecular Biology Applications:

Primary Use: Processes large volumes of samples for DNA/RNA extraction, protein purification, and enzyme assays requiring controlled low temperatures to prevent degradation of nucleic acids and proteins.
How it helps: Preserves the integrity of genetic material and proteins during processing, ensuring that molecular diagnostic tests accurately detect genetic disorders, infectious agents, and cancer markers.

5. Vaccine and Biopharmaceutical Production:

Primary Use: Critical for large-scale processing of temperature-sensitive biological materials including vaccines, recombinant proteins, and cell cultures requiring strict temperature control during centrifugation.
How it helps: Enables the large-scale manufacturing of vaccines and biologic drugs that protect millions of people from infectious diseases and treat chronic conditions like cancer and autoimmune disorders.

6. Cold Precipitation and Crystallization Studies:

Primary Use: Used in research and quality control applications requiring controlled low temperatures for precipitation of specific compounds or crystallization studies.
How it helps: Supports scientific discovery and pharmaceutical development by allowing researchers to isolate and study compounds that only separate from solution at cold temperatures.

7. Long-Duration Centrifugation Protocols:

Primary Use: Floor-standing cooling centrifuges are designed for extended runs (hours to days) required for density gradient separations, ultracentrifugation prep, and large-scale purification protocols where temperature stability is essential.
How it helps: Enables complex separation procedures that take hours or even days to complete, maintaining stable cold temperatures throughout to protect sensitive biological materials.

SECONDARY & SUPPORTIVE USES

1. Pharmaceutical Quality Control: Processing large batches of temperature-sensitive drug products and stability samples, ensuring that medications reaching patients are safe, pure, and effective.

2. Biotechnology Manufacturing: Large-scale production of monoclonal antibodies, recombinant proteins, and cell therapies requiring GMP-compliant processing with temperature control, bringing advanced treatments to patients.

3. Clinical Research and Biobanking: Processing and aliquoting large volumes of blood, plasma, and serum for biorepository storage with temperature control to preserve sample integrity, building resources for future research.

4. Veterinary Vaccine Production: Large-scale processing of veterinary biologicals requiring cold centrifugation, protecting animal health worldwide.

5. Food and Beverage Quality Control: Processing large samples for microbiological and chemical analysis requiring temperature control, ensuring food safety for consumers.

6. Environmental Sample Processing: Large-volume water and soil sample processing for contaminant analysis, monitoring environmental health and safety.

7. Industrial and Chemical Processing: Pilot-scale and production-scale separation of temperature-sensitive industrial compounds, supporting manufacturing across multiple industries.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Floor-standing, refrigerated centrifuge designed for high-capacity processing of temperature-sensitive biological samples.
Common Names: Floor Model Cooling Centrifuge, Refrigerated Floor Centrifuge, Large Capacity Refrigerated Centrifuge, Blood Bank Refrigerated Centrifuge, Cold Centrifuge.
Rotor Types:
- Swinging-Bucket Rotors: Multiple large buckets for processing blood bags, 500 mL-1 L bottles, and multiple tube sizes.
- Fixed-Angle Rotors: For higher RCF applications with large volumes.
- Continuous Flow Rotors: For processing very large volumes continuously.
- Cell Culture Rotors: Specialized for spinner flasks and cell culture vessels.
Rotor Capacity:
- Blood Bags: 4-12 blood bags per run.
- 500 mL Bottles: 4-8 bottles.
- 1 L Bottles: 4-6 bottles.
- 250 mL Bottles: 8-16 bottles.
- 50 mL Conical Tubes: 16-48 tubes.
- 15 mL Conical Tubes: 48-96 tubes.
- Blood Collection Tubes: 96-192 tubes.
- Microplates: 4-20 plates.
Maximum Speed: 4,000-8,000 RPM typical.
Maximum RCF: 4,000-12,000 x g.
Temperature Range: -10°C to +40°C, with precise control typically ±1°C.
Temperature Control: Advanced refrigeration system with rapid cooling and precise temperature maintenance.
Drive System: High-torque brushless induction motor for quiet, maintenance-free operation.
Display: Large digital LCD or color touchscreen showing speed, RCF, temperature, time, and program status.
Controls: Touchscreen or membrane keypad with programmable protocols.
Timing: Digital timer from 1-999 minutes or continuous run with hold function.
Program Memory: Stores 50-100 protocols for different applications.
Acceleration/Deceleration: 10-20 programmable profiles for gentle or rapid separation.
Imbalance Detection: Advanced imbalance detection with automatic shutoff.
Lid Lock: Heavy-duty automatic locking with safety sensors.
Vacuum System: Some models include vacuum system for reduced friction and temperature stability.

2. TECHNICAL & PERFORMANCE PROPERTIES

Speed Range: 500-8,000 RPM depending on model and rotor.
RCF Range: Up to 12,000 x g.
Temperature Control: ±1°C accuracy; rapid cool-down from ambient to 4°C in 10-20 minutes.
Rotor Options:
- Blood Bag Rotors: For 4-12 blood bags with inserts.
- Large Volume Bottle Rotors: For 500 mL-1 L bottles.
- Multi-Purpose Swing-out Rotors: Accept various tube racks and adapters.
- Fixed-Angle Rotors: For higher speed applications.
- Continuous Flow Rotors: For processing 10-100 L continuously.
- Microplate Rotors: For 4-20 microplates.
Acceleration/Deceleration Profiles: Multiple profiles for different sample types.
Noise Level: 60-75 dB depending on model and speed.
Power Requirements: 200-240 VAC, 50/60 Hz, 15-30 amps (requires dedicated circuit).
Refrigeration System: CFC-free refrigerants, environmentally friendly.

3. PHYSICAL & OPERATIONAL PROPERTIES

Dimensions: 80-120 cm × 90-150 cm × 100-180 cm (floor-standing).
Weight: 200-500 kg depending on model and configuration.
Construction: Heavy-duty steel with durable epoxy or stainless steel exterior; stainless steel bowl interior.
Display: Large color touchscreen (7-12 inches) with intuitive interface.
Rotor Exchange: Easy-change rotor system with automatic recognition and safety interlock.
Accessories: Comprehensive tube adapters, rotor exchange tools, leveling feet, casters for mobility.
Power Requirements: 200-240 VAC, 50/60 Hz, dedicated circuit required.
Installation: Professional installation required; needs adequate floor space and ventilation.
Certifications: Meets relevant safety and quality standards for medical devices and GMP manufacturing.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device (FDA, CE marked for IVD use); may require additional certifications for GMP manufacturing.
Safety Standards: Complies with IEC 61010-2-020 for safety requirements for centrifuges.
Imbalance Detection: Advanced multi-sensor imbalance detection with automatic shutoff.
Lid Lock: Heavy-duty electromechanical lock with redundant safety systems.
Emergency Lid Release: Manual release system accessible from outside.
Over-speed Protection: Prevents operation above rotor's maximum rated speed.
Rotor Recognition: Automatic rotor identification with speed limiting.
Temperature Monitoring: Continuous temperature monitoring with alarms and data logging.
Biohazard Safety: Aerosol-tight rotors and buckets certified for infectious samples.
Quality Management: Manufactured under ISO 13485 or ISO 9001; GMP-compliant options available.
Data Logging: Comprehensive run logs with temperature, speed, time, and imbalance events.

5. STORAGE & HANDLING ATTRIBUTES

Storage: Permanent installation in laboratory; not typically moved after installation.
Installation: Professional installation by certified technicians; requires adequate floor space, ventilation, and dedicated power circuit.
Cleaning: Regular cleaning of bowl, rotors, and buckets with approved disinfectants; stainless steel surfaces require proper care.
Rotor Care: Detailed rotor inspection log; regular professional inspection and certification; replace rotors per manufacturer schedule.
Calibration: Annual speed, temperature, and timer calibration verification by certified service provider.
Maintenance: Comprehensive preventive maintenance program per manufacturer schedule (quarterly, semi-annual, annual).
Validation: IQ/OQ/PQ documentation available for GMP-compliant installations.
Inspection: Daily visual inspection; regular professional maintenance and certification.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Large-scale, temperature-controlled centrifugation for blood banking, clinical laboratories, biopharmaceutical manufacturing, and research applications requiring precise temperature control.
Typical Clinical Protocols:
- Blood Bank Processing: 2,000-4,000 RPM at 4°C for 10-20 minutes.
- Coagulation Studies: 2,500-3,500 RPM at 4°C for 15 minutes.
- Cold Precipitation: 3,000-5,000 RPM at 2-8°C for 30-60 minutes.
- Plasma Preparation: 3,000-4,000 RPM at 4°C for 15 minutes.
- Platelet Processing: 1,000-2,000 RPM at 20-24°C (specific protocols).
Sample Compatibility:
- Blood Bags: Single, double, triple, quadruple blood bags.
- Blood Collection Tubes: All standard sizes (3-10 mL).
- Conical Tubes: 15 mL, 50 mL.
- Centrifuge Bottles: 250 mL, 500 mL, 1 L.
- Cell Culture Vessels: Spinner flasks, roller bottles.
- Microplates: 96-well, 384-well, deep-well.
Throughput: 100-1,000+ samples per hour depending on application and rotor configuration.
GMP Compliance: Models available with 21 CFR Part 11 compliant data logging for pharmaceutical manufacturing.

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Installation Safety: Professional installation required; ensure proper electrical supply and floor loading capacity.
Balancing Loads: Critical for large rotors; use precision balance; document load weights for sensitive applications.
Rotor Certification: Regular professional rotor inspection and certification; maintain detailed rotor log.
Temperature Monitoring: Verify temperature calibration regularly; use independent temperature monitoring for critical samples.
Aerosol Safety: Use certified aerosol-tight rotors for infectious samples; follow BSL-3/4 protocols as applicable.
Emergency Procedures: Posted emergency shutdown and spill procedures; trained personnel on all shifts.
Training: Comprehensive operator training required; refresher training annually.
Maintenance: Strict adherence to preventive maintenance schedule; never operate with known issues.
Load Limits: Never exceed rotor maximum speed or sample weight; document all loads.
Validation: For GMP applications, maintain full validation documentation.

2. FIRST AID MEASURES

Major Rotor Failure: Evacuate area immediately; do not open lid for 30 minutes. Call emergency services if injuries; contact the manufacturer for professional cleanup.
Biohazard Spill (Large Scale): Evacuate area; follow institutional BSL-3/4 spill protocol; professional decontamination required.
Refrigerant Leak: Evacuate area; ventilate; call facility maintenance; follow refrigerant safety protocols.
Chemical Spill (Large Volume): Evacuate if toxic; follow chemical spill protocol; use appropriate PPE and absorbent materials.
Electrical Fire: Disconnect power if safe; use CO₂ or dry chemical extinguisher; evacuate if fire spreads.
Personal Injury: Seek immediate medical attention; document incident.

3. FIRE FIGHTING MEASURES

Flammability: Electrical components and plastic parts combustible; refrigerant may be flammable (check specifications).
Extinguishing Media: For electrical fire, use CO₂ or dry chemical (Class C) extinguisher; CO₂ preferred to minimize equipment damage.
Power Off: Emergency shutoff switch should be clearly marked and accessible.
Large Equipment: Ensure fire departments are aware of equipment hazards; maintain clear access.

Floor Type Low Speed Cooling Centrifuge

Floor Type Low Speed Cooling Centrifuge

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Large-Volume Blood Separation with Temperature Control:

How it helps: Ensures that delicate blood components remain stable during processing, giving laboratory professionals and clinicians confidence that test results accurately reflect patient health rather than degradation during handling.

2. Blood Bank and Transfusion Service Processing:

Primary Use: Essential for preparing packed red blood cells, platelet concentrates, fresh frozen plasma, and cryoprecipitate from donated blood units, with refrigeration ensuring optimal preservation of blood components during processing.

How it helps: Makes the most of every blood donation by carefully separating whole blood into components that can help multiple patients, while refrigeration preserves these life-saving products until they are needed.

3. Cold Centrifugation for Coagulation Studies:

Primary Use: Maintains samples at 4°C during centrifugation to preserve coagulation factors (Factor V, VIII) and prevent cold activation of platelets, ensuring accurate PT, APTT, and factor assay results.

How it helps: Provides hematologists and coagulation specialists with reliable test results, ensuring that patients with bleeding disorders receive accurate diagnoses and appropriate treatment based on properly preserved samples.

4. Temperature-Sensitive Molecular Biology Applications:

Primary Use: Processes large volumes of samples for DNA/RNA extraction, protein purification, and enzyme assays requiring controlled low temperatures to prevent degradation of nucleic acids and proteins.

How it helps: Preserves the integrity of genetic material and proteins during processing, ensuring that molecular diagnostic tests accurately detect genetic disorders, infectious agents, and cancer markers.

5. Vaccine and Biopharmaceutical Production:

Primary Use: Critical for large-scale processing of temperature-sensitive biological materials including vaccines, recombinant proteins, and cell cultures requiring strict temperature control during centrifugation.

How it helps: Enables the large-scale manufacturing of vaccines and biologic drugs that protect millions of people from infectious diseases and treat chronic conditions like cancer and autoimmune disorders.

6. Cold Precipitation and Crystallization Studies:

Primary Use: Used in research and quality control applications requiring controlled low temperatures for precipitation of specific compounds or crystallization studies.

How it helps: Supports scientific discovery and pharmaceutical development by allowing researchers to isolate and study compounds that only separate from solution at cold temperatures.

7. Long-Duration Centrifugation Protocols:

Primary Use: Floor-standing cooling centrifuges are designed for extended runs (hours to days) required for density gradient separations, ultracentrifugation prep, and large-scale purification protocols where temperature stability is essential.

How it helps: Enables complex separation procedures that take hours or even days to complete, maintaining stable cold temperatures throughout to protect sensitive biological materials.

SECONDARY & SUPPORTIVE USES

1. Pharmaceutical Quality Control: Processing large batches of temperature-sensitive drug products and stability samples, ensuring that medications reaching patients are safe, pure, and effective.

2. Biotechnology Manufacturing: Large-scale production of monoclonal antibodies, recombinant proteins, and cell therapies requiring GMP-compliant processing with temperature control, bringing advanced treatments to patients.

3. Clinical Research and Biobanking: Processing and aliquoting large volumes of blood, plasma, and serum for biorepository storage with temperature control to preserve sample integrity, building resources for future research.

4. Veterinary Vaccine Production: Large-scale processing of veterinary biologicals requiring cold centrifugation, protecting animal health worldwide.

5. Food and Beverage Quality Control: Processing large samples for microbiological and chemical analysis requiring temperature control, ensuring food safety for consumers.

6. Environmental Sample Processing: Large-volume water and soil sample processing for contaminant analysis, monitoring environmental health and safety.

7. Industrial and Chemical Processing: Pilot-scale and production-scale separation of temperature-sensitive industrial compounds, supporting manufacturing across multiple industries.

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Floor-standing, refrigerated centrifuge designed for high-capacity processing of temperature-sensitive biological samples.

Common Names: Floor Model Cooling Centrifuge, Refrigerated Floor Centrifuge, Large Capacity Refrigerated Centrifuge, Blood Bank Refrigerated Centrifuge, Cold Centrifuge.

Rotor Types:

Swinging-Bucket Rotors: Multiple large buckets for processing blood bags, 500 mL-1 L bottles, and multiple tube sizes.

Fixed-Angle Rotors: For higher RCF applications with large volumes.

Continuous Flow Rotors: For processing very large volumes continuously.

Cell Culture Rotors: Specialized for spinner flasks and cell culture vessels.

Rotor Capacity:

Blood Bags: 4-12 blood bags per run.

500 mL Bottles: 4-8 bottles.

1 L Bottles: 4-6 bottles.

250 mL Bottles: 8-16 bottles.

50 mL Conical Tubes: 16-48 tubes.

15 mL Conical Tubes: 48-96 tubes.

Blood Collection Tubes: 96-192 tubes.

Microplates: 4-20 plates.

Maximum Speed: 4,000-8,000 RPM typical.

Maximum RCF: 4,000-12,000 x g.

Temperature Range: -10°C to +40°C, with precise control typically ±1°C.

Temperature Control: Advanced refrigeration system with rapid cooling and precise temperature maintenance.

Drive System: High-torque brushless induction motor for quiet, maintenance-free operation.

Display: Large digital LCD or color touchscreen showing speed, RCF, temperature, time, and program status.

Controls: Touchscreen or membrane keypad with programmable protocols.

Timing: Digital timer from 1-999 minutes or continuous run with hold function.

Program Memory: Stores 50-100 protocols for different applications.

Acceleration/Deceleration: 10-20 programmable profiles for gentle or rapid separation.

Imbalance Detection: Advanced imbalance detection with automatic shutoff.

Lid Lock: Heavy-duty automatic locking with safety sensors.

Vacuum System: Some models include vacuum system for reduced friction and temperature stability.

2. TECHNICAL & PERFORMANCE PROPERTIES

Speed Range: 500-8,000 RPM depending on model and rotor.

RCF Range: Up to 12,000 x g.

Temperature Control: ±1°C accuracy; rapid cool-down from ambient to 4°C in 10-20 minutes.

Rotor Options:

Blood Bag Rotors: For 4-12 blood bags with inserts.

Large Volume Bottle Rotors: For 500 mL-1 L bottles.

Multi-Purpose Swing-out Rotors: Accept various tube racks and adapters.

Fixed-Angle Rotors: For higher speed applications.

Continuous Flow Rotors: For processing 10-100 L continuously.

Microplate Rotors: For 4-20 microplates.

Acceleration/Deceleration Profiles: Multiple profiles for different sample types.

Noise Level: 60-75 dB depending on model and speed.

Power Requirements: 200-240 VAC, 50/60 Hz, 15-30 amps (requires dedicated circuit).

Refrigeration System: CFC-free refrigerants, environmentally friendly.

3. PHYSICAL & OPERATIONAL PROPERTIES

Dimensions: 80-120 cm × 90-150 cm × 100-180 cm (floor-standing).

Weight: 200-500 kg depending on model and configuration.

Construction: Heavy-duty steel with durable epoxy or stainless steel exterior; stainless steel bowl interior.