Touch Screen UV-Vis Spectrophotometer

Touch Screen UV-Vis Spectrophotometer

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Nucleic Acid Quantification and Purity Assessment for Molecular Diagnostics
Primary Use: Provides a single-beam UV-Vis spectrophotometer with a 10.1 inch high resolution color touch screen, a holographic grating monochromator, and a digital photodiode detector, used for the accurate quantification and purity assessment of DNA, RNA, and oligonucleotides in clinical molecular diagnostics, including infectious disease testing, oncology biomarker analysis, and genetic screening workflows.

How it helps: For the molecular diagnostics scientist and clinical laboratory technologist, the touch screen spectrophotometer measures absorbance at 260 nm for nucleic acid concentration and automatically calculates 260/280 and 260/230 purity ratios, ensuring that extracted DNA or RNA meets stringent quality standards for downstream PCR, qPCR, or next generation sequencing. The instrument’s stray light of ≤0.03% T at 220 nm and 360 nm and low noise of ±0.0002 A at 500 nm deliver exceptional accuracy and precision. For the patient, precise nucleic acid quantification and purity confirmation directly support accurate detection of HIV, hepatitis, COVID-19, cancer associated mutations, and inherited genetic disorders, reducing the risk of false negatives caused by contaminated or degraded samples.

2. Enzymatic Activity and Kinetic Monitoring for Clinical Enzyme Assays
Primary Use: Performs built-in kinetics analysis mode for real time monitoring of absorbance changes during enzymatic reactions, used for the clinical determination of enzyme activities including alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase, and creatine kinase in patient serum samples.

How it helps: For the clinical chemistry laboratory scientist, the touch screen spectrophotometer’s kinetics mode tracks absorbance changes at specific wavelengths over time and automatically calculates enzyme reaction rates in units per liter. The newly designed wavelength drive mechanism improves wavelength accuracy and repeatability while reducing operational noise. For the patient undergoing liver function testing, cardiac enzyme panels, or metabolic disorder screening, accurate enzyme activity results directly guide diagnosis of hepatitis, myocardial infarction, liver disease, and other conditions, as well as monitoring of disease progression and treatment response.

3. Clinical Chemistry Analysis for Routine Patient Sample Testing
Primary Use: Used for the quantitative analysis of blood and serum components including glucose, total cholesterol, triglycerides, total protein, albumin, total bilirubin, direct bilirubin, creatinine, and uric acid, using photometric measurement mode with standard curve quantification, all executable directly on the instrument without a computer.

How it helps: For the clinical chemistry technologist, the touch screen spectrophotometer independently performs photometric measurement and quantitative analysis using standard curves on the host instrument. The powerful data storage function saves various types of data and spectra, and the instrument maintains data after power failure with a hold function. For the patient, reliable measurements of blood glucose, lipid panels, kidney function markers, and liver enzymes support routine health screening, chronic disease management for diabetes, hyperlipidemia, and chronic kidney disease, and acute care diagnostics, enabling timely clinical interventions.

4. ELISA Endpoint Detection for Clinical Immunology
Primary Use: Serves as a detection platform for enzyme linked immunosorbent assay (ELISA) in clinical immunology, measuring the absorbance of final colored products at wavelengths such as 450 nm, 492 nm, and 650 nm, with multi-wavelength measurement mode for simultaneous analysis at multiple wavelengths.

How it helps: For the clinical immunology technologist, the touch screen spectrophotometer’s multi-wavelength testing function completes absorbance measurements at several wavelengths in a single operation, rapidly calculating the concentration of target analytes. The instrument uses a digital photodiode detector with low stray light and low noise, ensuring high within-run and between-run consistency for high throughput immunoassays. For the patient, accurate ELISA endpoint detection supports reliable diagnosis of infectious diseases, autoimmune disorders, and allergies, helping clinicians develop appropriate treatment plans.

SECONDARY & SUPPORTIVE USES

1. Ultra-micro nucleic acid and protein measurement (with optional accessory): When equipped with an ultra-micro cuvette or micro-volume sample holder, measures nucleic acid and protein concentrations directly from as little as 0.5 μL to 2 μL of sample without dilution, particularly suitable for precious or limited volume clinical specimens.

2. Drug dissolution testing for pharmaceutical quality control: Quantifies drug release from solid dosage forms such as tablets and capsules in dissolution media, monitoring drug concentration over time using wavelength scanning mode, meeting GMP compliance requirements for pharmaceutical QC laboratories.

3. Bacterial growth density measurement in clinical microbiology: Measures optical density at 600 nm (OD600) of bacterial and yeast cultures to monitor microbial growth kinetics, optimize harvest timing, determine minimum inhibitory concentrations, and perform antimicrobial susceptibility testing.

4. Bilirubin and hemoglobin measurement in neonatal screening: Quantifies total and direct bilirubin levels in neonatal serum for jaundice screening and severity assessment, and measures hemoglobin for anemia screening in newborn and pediatric populations.

5. Water quality testing for clinical utilities: Monitors water quality parameters including residual chlorine, nitrate, nitrite, and total organic carbon in purified water used in clinical laboratories, dialysis centers, and pharmacy compounding areas, using appropriate colorimetric reagent kits.

6. Therapeutic drug monitoring: Quantifies concentrations of narrow therapeutic window drugs in patient serum or plasma, including antiepileptics such as phenytoin and valproic acid, immunosuppressants such as cyclosporine and tacrolimus, and certain antibiotics such as vancomycin and gentamicin, using standard curve quantification methods.

7. Veterinary diagnostic sample analysis: Performs the same range of clinical chemistry assays, protein quantification, nucleic acid purity assessment, and enzyme activity determination for veterinary patient samples in animal health diagnostic laboratories and veterinary teaching hospitals.

8. Traditional Chinese medicine and herbal product quality control: Detects the content of active ingredients such as total flavonoids, total polyphenols, and total saponins in herbal extracts during research and production of traditional Chinese medicines, using absorbance measurements at specific wavelengths.

9. Pharmaceutical raw material testing: Quantifies the concentration of active pharmaceutical ingredients and excipients during incoming raw material quality control in GMP laboratories, ensuring all batches meet specification before use in drug manufacturing for colorimetric assays.

10. Food safety and nutritional analysis: Quantifies caffeine, total polyphenols, vitamin C, nitrites, nitrates, and synthetic food colorants in food and beverage samples for food safety testing and nutritional labeling compliance analysis.

11. Academic research and teaching: Serves as an intuitive teaching tool for students learning spectrophotometric analysis techniques in clinical laboratory science, biochemistry, and molecular biology courses, with a graphical user interface that visually demonstrates the principles of spectrum scanning, quantitative analysis, and kinetics monitoring.