Cell Lysis

The  High Shear Homogenizer is a powerful benchtop rotor-stator homogenizer featuring a 500W AC carbon brush motor, variable speed control (10,000-30,000 rpm with 6 speed settings), interchangeable autoclavable 316L stainless steel dispersing shafts, and a wide working volume range of 10-40,000 mL, designed for rapid homogenization, dispersion, and emulsification of biological tissues, pharmaceutical formulations, and chemical samples in clinical diagnostic, pharmaceutical, and research laboratories .

Key features include a 500W high-power motor handling samples up to 10,000 mPa·s viscosity , 6-stage adjustable speed dial for precise control of homogenization intensity , interchangeable dispersing shafts ( High Shear Homogenize/1 for solid-liquid mixing and tissue homogenization;  High Shear Homogenize/2 for emulsification and cream preparation) , fully autoclavable 316L stainless steel construction with PTFE seals for chemical resistance and contamination prevention, automatic overload protection and smooth motor start for safety and extended motor life, emergency stop safety switch for immediate shutdown, and compact (75 × 75 × 280 mm) and lightweight (1.7 kg) design for benchtop or stand-mounted operation . An optional H-600 stand enables hands-free, stationary operation .

For the histotechnologist and pathologist, the  High Shear Homogenize processes tough tissue samples such as muscle, liver, breast, and other organs in seconds—enabling rapid preparation of homogenized specimens for histological examination, immunohistochemistry, and diagnostic pathology . For the molecular biologist, it supports cell disruption and nucleic acid extraction for PCR-based infectious disease testing, genetic screening, and oncology biomarker detection. For the pharmaceutical QC chemist, it processes high-viscosity formulations, creams, and ointments for stability testing and quality release.

For the patient undergoing biopsy for suspected cancer, inflammatory disease, or infectious condition, the High Shear Homogenize rapid tissue homogenization reduces turnaround time for diagnostic results, enabling earlier diagnosis and treatment initiation . For patients requiring pharmaceutical products, consistent formulation testing ensures that medications, topical creams, and biological products meet quality standards for safety and efficacy. For patients requiring molecular diagnostic testing, efficient cell lysis and nucleic acid extraction ensure accurate PCR and sequencing results that guide appropriate treatment decisions across clinical pathology, molecular diagnostics, infectious disease testing, and pharmaceutical quality control applications.