Digital Dry Bath (HB120-S)

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The Digital Dry Bath (HB120-S) is a compact benchtop dry thermostat with extended high-temperature capability up to 120°C, designed for specialized molecular biology applications, protein denaturation, and high-temperature diagnostic assay preparation in clinical and research laboratories . With a temperature range from room temperature +5°C to 120°C and temperature control accuracy of ±0.5°C, this dry bath provides consistent, uniform heating for protocols requiring temperatures above the standard 100°C boiling point .

The HB120-S features a microprocessor-controlled system with LED display for real-time temperature and time monitoring, an intuitive control knob for simple operation without complex menus, and interchangeable aluminum heating blocks compatible with various tube formats and sizes . The unit supports both timing mode (0 to 99 hours 59 minutes) and continuous operation mode, with built-in temperature self-calibration function for long-term accuracy .

For the molecular biologist and clinical laboratory scientist, the HB120-S supports complete heat inactivation of restriction enzymes and heat-labile enzymes (preventing interference with downstream diagnostic assays), protein denaturation for SDS-PAGE and Western blotting, DNA denaturation for GC-rich templates and challenging PCR protocols, and high-temperature sample preparation for specialized diagnostic workflows .

Safety features include over-temperature protection and an insulated lid that prevents heat loss and contamination . The extended temperature range (up to 120°C) enables specialized protocols requiring higher temperatures than standard dry baths, making the HB120-S an essential tool for reference laboratories and molecular diagnostics facilities.

For the patient undergoing specialized molecular testing, the HB120-S’s extended temperature capability ensures complete enzyme inactivation, thorough DNA denaturation for challenging templates, and reliable high-temperature sample preparation—supporting accurate diagnostic results for complex genetic conditions, infectious diseases, and oncology testing .

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Categories: LABORATORY EQUIPMENT AND SUPPLIES, Incubators and Ovens Tags: Clinical Laboratory Equipment, Digital Dry Bath Incubator, DLAB HB120-S, DNA Denaturation, Enzyme Inactivation, Extended Range Dry Bath, GC-Rich PCR, HB120-S Digital Dry Bath, High-Temperature Dry Bath, High-Temperature Heating, Molecular Diagnostics

Description

Digital Dry Bath (HB120-S)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. High-Temperature Incubation for Molecular Diagnostics

Primary Use: Provides a digital dry bath with a temperature range from room temperature +5°C to 120°C, enabling high-temperature incubation for specialized molecular biology protocols, protein denaturation, and diagnostic assay preparation .
How it helps: For the molecular biologist and clinical laboratory scientist, the HB120-S delivers precise temperature control (up to 120°C) with LED display and user-friendly setting knob—essential for protocols requiring temperatures above the standard 100°C boiling point, such as certain inactivation steps and specialized nucleic acid procedures . For the patient, access to higher temperature capabilities ensures that specialized diagnostic assays can be performed in-house, reducing referral delays and accelerating diagnosis.

2. Complete Enzyme Inactivation and Protein Denaturation

Primary Use: Used for complete heat inactivation of enzymes (including heat-labile enzymes and restriction enzymes) and protein denaturation at temperatures up to 120°C .
How it helps: For the clinical chemist and molecular biologist, the HB120-S’s extended temperature range ensures complete, irreversible inactivation of enzymes that may interfere with downstream diagnostic assays—improving assay specificity and reducing false-positive results. For the patient, thorough enzyme inactivation prevents erroneous test results that could lead to misdiagnosis or inappropriate treatment.

3. DNA Denaturation for High-Stringency Protocols

Primary Use: Provides controlled high-temperature heating for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows requiring stringent denaturation conditions .
How it helps: For the molecular biologist, the HB120-S’s precise temperature control (up to 120°C) and excellent temperature uniformity ensures complete separation of double-stranded DNA even for GC-rich templates—critical for PCR, sequencing, and hybridization-based assays where incomplete denaturation leads to failed reactions . This supports accurate genetic testing for challenging templates.

4. High-Temperature Sample Preparation for Specialized Assays

Primary Use: Used for sample preparation requiring elevated temperatures, including heat treatment of clinical specimens for certain pathogen inactivation protocols before molecular testing .
How it helps: For the clinical laboratory scientist and infection control specialist, the HB120-S provides reliable high-temperature treatment of samples for downstream diagnostic workflows . For the patient, proper high-temperature sample preparation ensures that infectious agents are appropriately inactivated before testing, reducing laboratory-acquired infection risk while preserving nucleic acid integrity for accurate detection.

SECONDARY & SUPPORTIVE USES

1. Restriction Enzyme Heat Inactivation: Used for complete inactivation of restriction enzymes after DNA digestion to prevent interference with subsequent ligation or amplification steps.

2. Protein Purification and Western Blotting: Supports protein denaturation steps at elevated temperatures for SDS-PAGE sample preparation.

3. Nucleic Acid Extraction from Difficult Samples: Provides heating for cell lysis and protein digestion steps in DNA/RNA extraction from tissue or difficult sample types.

4. ELISA and Immunoassay High-Temperature Incubation: Supports specialized ELISA protocols requiring elevated temperature incubation.

5. Lipid and Cholesterol Analysis: Used for heating samples in lipid profiling and cholesterol fractionation protocols requiring elevated temperatures.

6. Histology and Pathology Tissue Processing: Used for warming embedding media and specialized processing solutions requiring higher temperatures.

7. Pharmaceutical Quality Control Stability Testing: Supports stability testing of pharmaceutical products at elevated temperatures.

8. Research and Academic Laboratories: Supports specialized research applications requiring incubation above 100°C.

9. Veterinary Diagnostic Laboratory: Supports specialized testing protocols requiring high-temperature incubation.

10. Clinical Chemistry Specialized Assays: Used for assays requiring elevated temperatures beyond standard 37°C or 56°C incubation.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: A digital dry bath with extended high-temperature capability (up to 120°C), designed for specialized molecular biology applications, protein denaturation, and high-temperature diagnostic assay preparation .
Designation: HB120-S Digital Dry Bath, High-Temperature Dry Bath, Digital Dry Bath Incubator, Extended Range Dry Bath, DLAB HB120-S, High-Temperature Heating Thermostat .
Key Components:
- Heating Block: Interchangeable aluminum block compatible with various tube sizes and formats .
- Microprocessor Controller: Regulates temperature with automatic feedback for precise control up to 120°C .
- LED Display: Digital display for real-time temperature and time monitoring .
- Control Knob: User-friendly setting knob for simple operation .
- Insulated Lid: Lid for heat preservation, temperature stability, and contamination prevention .

2. TECHNICAL & PERFORMANCE PROPERTIES

Temperature Range: Room temperature +5°C to 120°C .
Temperature Control Accuracy: ±0.5°C (at 20-45°C) .
Temperature Uniformity: ±0.2°C to ±0.5°C (max. ±0.5°C) .
Temperature Setting Display: Three-digit LED display with 0.1°C resolution .
Time Setting Range: 0 minutes to 99 hours 59 minutes .
Work Mode: Timing or continuous operation .
Heating Power: 160W .
Voltage/Frequency: 100-240V, 50/60Hz .
Dimensions (W × D × H): Compact benchtop footprint .
Weight: Lightweight design for benchtop use .
Calibration: Built-in temperature self-calibration function .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Durable outer housing designed for extended temperature operation up to 120°C .
Control System: Microprocessor-controlled with LED digital display .
Operation Modes: Timing mode (0-99h59min) and continuous operation mode .
Block Compatibility: Accepts various optional interchangeable heating blocks for different tube formats .
Calibration: Built-in temperature calibration function .
Safety Features: Over-temperature protection .
User Interface: Intuitive control knob for easy operation without complex menus .
Portability: Compact benchtop design .
Maintenance: Simple cleaning; interchangeable blocks require no tools.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device for clinical diagnostic use .
Safety Features: Over-temperature protection system, lid for heat preservation and contamination prevention .
High-Temperature Safety: Extended safety margins for 120°C operation .
Electrical Safety: Universal voltage (100-240V, 50/60Hz); over-current protection; reverse voltage protection .
GLP Compliance: Timer and temperature display support GLP documentation .
Temperature Calibration: Built-in self-calibration function ensures long-term accuracy .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.
Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.
Block Maintenance: Remove and clean heating block with mild detergent; dry thoroughly before reinstallation.
Inspection: Inspect block contacts for residue or damage before each use; clean if needed.
Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination.
Calibration: Perform periodic temperature calibration per manufacturer guidelines.
Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: High-temperature enzyme inactivation, protein denaturation, DNA denaturation for challenging templates, and specialized molecular biology workflows in clinical diagnostic and research laboratories .
Clinical Role: Essential specialized sample preparation equipment in clinical diagnostic laboratories, molecular diagnostics labs, research facilities, and reference laboratories requiring extended temperature capabilities .

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Temperature Setting: Do not exceed recommended temperatures for specific sample types; excessive heat may denature proteins or degrade analytes; use caution when setting temperatures above 100°C .
Block Installation: Ensure heating block is properly seated before operation.
Temperature Verification: Allow unit to reach set temperature before loading temperature-sensitive samples; verify temperature stability before use .
Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination; use caution—lid will be hot at high temperatures .
Hot Surface Warning: Surfaces may become very hot during extended operation at temperatures above 100°C; use caution when handling .
Cleaning: Clean spills immediately; disinfect heating block if biological materials are involved; allow block to cool completely before removal .
Placement: Place on firm, flat, level, heat-resistant surface; ensure adequate clearance around unit for ventilation .
Training: Only trained laboratory personnel should operate the HB120-S for clinical diagnostic applications .

2. FIRST AID MEASURES

Burn/Scald: If hot heating block or surface contacts skin, cool affected area immediately with cool running water for at least 15 minutes; seek medical attention for severe burns .
Sample Spillage: If biological sample spills into unit, disconnect power, allow to cool completely, disinfect area immediately with 70% ethanol or appropriate disinfectant.
Electrical Malfunction: If unit shows signs of electrical malfunction, disconnect power immediately; do not attempt to operate; contact service personnel.
Calibration Verification: If test results are inconsistent, perform temperature calibration to verify accuracy before proceeding with diagnostic testing.

3. FIRE FIGHTING MEASURES

Flammability: Plastic housing and electrical components may burn.
Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
Fire Response: Unplug unit immediately; do not use water on electrical fire.

Digital Dry Bath (HB120-S)

Digital Dry Bath (HB120-S)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. High-Temperature Incubation for Molecular Diagnostics

Primary Use: Provides a digital dry bath with a temperature range from room temperature +5°C to 120°C, enabling high-temperature incubation for specialized molecular biology protocols, protein denaturation, and diagnostic assay preparation .

2. Complete Enzyme Inactivation and Protein Denaturation

Primary Use: Used for complete heat inactivation of enzymes (including heat-labile enzymes and restriction enzymes) and protein denaturation at temperatures up to 120°C .

3. DNA Denaturation for High-Stringency Protocols

Primary Use: Provides controlled high-temperature heating for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows requiring stringent denaturation conditions .

4. High-Temperature Sample Preparation for Specialized Assays

Primary Use: Used for sample preparation requiring elevated temperatures, including heat treatment of clinical specimens for certain pathogen inactivation protocols before molecular testing .

SECONDARY & SUPPORTIVE USES

1. Restriction Enzyme Heat Inactivation: Used for complete inactivation of restriction enzymes after DNA digestion to prevent interference with subsequent ligation or amplification steps.

2. Protein Purification and Western Blotting: Supports protein denaturation steps at elevated temperatures for SDS-PAGE sample preparation.

3. Nucleic Acid Extraction from Difficult Samples: Provides heating for cell lysis and protein digestion steps in DNA/RNA extraction from tissue or difficult sample types.

4. ELISA and Immunoassay High-Temperature Incubation: Supports specialized ELISA protocols requiring elevated temperature incubation.

5. Lipid and Cholesterol Analysis: Used for heating samples in lipid profiling and cholesterol fractionation protocols requiring elevated temperatures.

6. Histology and Pathology Tissue Processing: Used for warming embedding media and specialized processing solutions requiring higher temperatures.

7. Pharmaceutical Quality Control Stability Testing: Supports stability testing of pharmaceutical products at elevated temperatures.

8. Research and Academic Laboratories: Supports specialized research applications requiring incubation above 100°C.

9. Veterinary Diagnostic Laboratory: Supports specialized testing protocols requiring high-temperature incubation.

10. Clinical Chemistry Specialized Assays: Used for assays requiring elevated temperatures beyond standard 37°C or 56°C incubation.

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: A digital dry bath with extended high-temperature capability (up to 120°C), designed for specialized molecular biology applications, protein denaturation, and high-temperature diagnostic assay preparation .

Designation: HB120-S Digital Dry Bath, High-Temperature Dry Bath, Digital Dry Bath Incubator, Extended Range Dry Bath, DLAB HB120-S, High-Temperature Heating Thermostat .

Key Components:

Heating Block: Interchangeable aluminum block compatible with various tube sizes and formats .

Microprocessor Controller: Regulates temperature with automatic feedback for precise control up to 120°C .

LED Display: Digital display for real-time temperature and time monitoring .

Control Knob: User-friendly setting knob for simple operation .

Insulated Lid: Lid for heat preservation, temperature stability, and contamination prevention .

2. TECHNICAL & PERFORMANCE PROPERTIES

Temperature Range: Room temperature +5°C to 120°C .

Temperature Control Accuracy: ±0.5°C (at 20-45°C) .

Temperature Uniformity: ±0.2°C to ±0.5°C (max. ±0.5°C) .

Temperature Setting Display: Three-digit LED display with 0.1°C resolution .

Time Setting Range: 0 minutes to 99 hours 59 minutes .

Work Mode: Timing or continuous operation .

Heating Power: 160W .

Voltage/Frequency: 100-240V, 50/60Hz .

Dimensions (W × D × H): Compact benchtop footprint .

Weight: Lightweight design for benchtop use .

Calibration: Built-in temperature self-calibration function .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Durable outer housing designed for extended temperature operation up to 120°C .

Control System: Microprocessor-controlled with LED digital display .

Operation Modes: Timing mode (0-99h59min) and continuous operation mode .

Block Compatibility: Accepts various optional interchangeable heating blocks for different tube formats .

Calibration: Built-in temperature calibration function .

Safety Features: Over-temperature protection .

User Interface: Intuitive control knob for easy operation without complex menus .

Portability: Compact benchtop design .

Maintenance: Simple cleaning; interchangeable blocks require no tools.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device for clinical diagnostic use .

Safety Features: Over-temperature protection system, lid for heat preservation and contamination prevention .

High-Temperature Safety: Extended safety margins for 120°C operation .

Electrical Safety: Universal voltage (100-240V, 50/60Hz); over-current protection; reverse voltage protection .

GLP Compliance: Timer and temperature display support GLP documentation .

Temperature Calibration: Built-in self-calibration function ensures long-term accuracy .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.

Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.

Block Maintenance: Remove and clean heating block with mild detergent; dry thoroughly before reinstallation.

Inspection: Inspect block contacts for residue or damage before each use; clean if needed.

Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination.

Calibration: Perform periodic temperature calibration per manufacturer guidelines.

Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: High-temperature enzyme inactivation, protein denaturation, DNA denaturation for challenging templates, and specialized molecular biology workflows in clinical diagnostic and research laboratories .

Clinical Role: Essential specialized sample preparation equipment in clinical diagnostic laboratories, molecular diagnostics labs, research facilities, and reference laboratories requiring extended temperature capabilities .

1. SAFETY PRECAUTIONS

Temperature Setting: Do not exceed recommended temperatures for specific sample types; excessive heat may denature proteins or degrade analytes; use caution when setting temperatures above 100°C .

Block Installation: Ensure heating block is properly seated before operation.

Temperature Verification: Allow unit to reach set temperature before loading temperature-sensitive samples; verify temperature stability before use .

Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination; use caution—lid will be hot at high temperatures .

Hot Surface Warning: Surfaces may become very hot during extended operation at temperatures above 100°C; use caution when handling .

Cleaning: Clean spills immediately; disinfect heating block if biological materials are involved; allow block to cool completely before removal .

Placement: Place on firm, flat, level, heat-resistant surface; ensure adequate clearance around unit for ventilation .

Training: Only trained laboratory personnel should operate the HB120-S for clinical diagnostic applications .