Pilot Scale Digital Control Rotary Evaporator (RE2000-E)

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The Pilot Scale Digital Control Rotary Evaporator (RE2000-E) is a pilot-scale, digital distillation system designed for efficient and gentle removal of solvents from samples by evaporation under reduced pressure for pilot production and biopharmaceutical manufacturing . Featuring a 20L evaporating flask capacity, 5.0 L/h evaporation rate (75% alcohol), and 4000W heating power (water bath 20-100°C / oil bath 20-180°C optional), this pilot-scale unit provides precise temperature control (PID control, ±1°C), rotation speed (20-130 rpm), and timer (0-999 minutes) control for large-volume processing .
Key features include a large LCD digital display for real-time monitoring of temperature, speed, direction, and time; stepless automatic motorized lift with 180mm stroke for smooth and silent operation; and a double-layer high-efficiency condenser with large cooling surface area and anti-backflow design for high-efficiency sample recovery . The heating bath features switchable water/oil heating modes, Teflon-coated inner layer for corrosion resistance and easy cleaning, and special insulation design that keeps outer surface temperature low to avoid operator burns . The professional PTFE sealing system provides high temperature resistance, corrosion resistance, and durability for extended service life . The automatic switching valve enables continuous collection of distillate without compromising system vacuum or solvent distillation, significantly increasing throughput for industrial applications .
For the bioprocess engineer and pharmaceutical manufacturing scientist, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) supports large-scale concentration of bioreactor harvests, purification of bulk active pharmaceutical ingredients (APIs), solvent recovery from pilot production runs, pilot-scale natural product extraction for nutraceutical manufacturing, high-volume solvent recovery for waste reduction, and pilot-scale concentration for cosmetics and food industry production . Safety features include motor overcurrent protection, earth leakage protection, dry heating protection (anti-dry burning), over-temperature protection, and automatic lift stop on power failure .
Continuous feeding capability, digital steam temperature sensing device (real-time feedback of solvent steam temperature for adjusting appropriate vacuum degree), forward and reverse rotation function (suitable for concentration of samples containing powder or solid particles), and optional vacuum controller for automated solvent separation ensure versatile, efficient operation for industrial manufacturing . With a compact footprint (900 × 490 × 1320mm) and pilot-scale capacity, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) is an essential instrument for pharmaceutical manufacturing, bioprocessing, chemical production, cosmetics manufacturing, food industry quality control, and pilot plant operations .
Description

 Pilot Scale Digital Control Rotary Evaporator (RE2000-E)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Large-Scale Solvent Removal for Pilot Production and Biopharmaceutical Manufacturing
  • Primary Use: Provides a pilot-scale digital rotary evaporator with a 20L evaporating flask capacity, 5.0 L/h evaporation rate (75% alcohol), and 4000W heating power (water bath 20-100°C / oil bath 20-180°C optional), designed for efficient and gentle removal of solvents from large-volume samples in pilot production and biopharmaceutical manufacturing .
  • How it helps: For the bioprocess engineer and pharmaceutical manufacturing scientist, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) enables large-scale concentration of bioreactor harvests, purification of bulk active pharmaceutical ingredients (APIs), and solvent recovery from pilot production runs—significantly scaling up production capacity from laboratory-scale to pilot-plant volumes. For the patient, efficient large-scale pharmaceutical manufacturing ensures consistent supply of high-quality medications and accelerates the transition of new drugs from research to clinical availability.
2. Purification of Active Pharmaceutical Ingredients (APIs) for Drug Manufacturing
  • Primary Use: Supports the large-scale purification and isolation of active pharmaceutical ingredients by removing organic synthesis solvents from multi-kilogram batches through controlled evaporation and condensation processes under reduced pressure (ultimate vacuum 9 mbar) .
  • How it helps: For the pharmaceutical production chemist and quality assurance specialist, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) precise PID temperature control (±1°C), large LCD display, and programmable timer (0-999 minutes) ensure consistent, reproducible purification results across large batch sizes for commercial drug manufacturing . For the patient, rigorous large-scale purification ensures product safety, purity, and consistent therapeutic efficacy in every batch of medication.
3. Natural Product Extraction for Nutraceutical and Pharmaceutical Development
  • Primary Use: Used for the large-scale extraction, concentration, and purification of natural products, botanical extracts, and active ingredients from plant materials for nutraceutical, pharmaceutical, and dietary supplement development .
  • How it helps: For the industrial chemist and nutraceutical production manager, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) 20L evaporating flask, double-layer high-efficiency condenser with large cooling surface area, and 180mm motorized lift enable efficient, reproducible extraction workflows for batch-to-batch quality testing at pilot scale . For the patient, accurate quality control of natural health products and nutraceutical ingredients ensures product safety, purity, and consistent therapeutic efficacy.
4. High-Volume Solvent Recovery and Industrial Waste Reduction
  • Primary Use: Recovers and recycles high-purity solvents from pilot-scale laboratory waste streams, reducing operational costs and minimizing environmental impact of hazardous chemical disposal, with evaporation capacity of 5.0 L/h (75% alcohol evaporation) .
  • How it helps: For the environmental compliance officer and industrial laboratory manager, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) automatic switching valve allows continuous collection of distillate without compromising system vacuum or solvent distillation—enabling efficient recovery of valuable solvents and reducing hazardous waste disposal volumes . For the patient and community, reduced solvent waste and lower manufacturing costs support sustainable healthcare practices and responsible industrial resource management.
5. Pilot-Scale Concentration in Cosmetics and Food Industry Production
  • Primary Use: Supports the concentration of active cosmetic ingredients, flavor compounds, and bioactive food extracts for commercial product manufacturing in cosmetics and food industry applications .
  • How it helps: For the industrial formulation scientist and quality control manager, the Pilot Scale Digital Control Rotary Evaporator (RE2000-E) wide temperature range (room temperature to 180°C with optional oil bath), adjustable immersion angle, and reversible rotation direction (clockwise/counterclockwise with forward/reverse function for drying processes) ensure efficient, reproducible concentration workflows for batch-to-batch quality testing at pilot production scales . For the patient and consumer, consistent quality control of cosmetics and food ingredients ensures product safety, purity, and reliable performance.

SECONDARY & SUPPORTIVE USES

1. Pilot-Scale Bioprocessing and Fermentation Harvest Concentration: Used for concentrating large volumes of cell culture supernatants, fermentation broths, and bioreactor harvests for downstream purification in biopharmaceutical pilot plants .
2. Industrial Chemical Synthesis and Petrochemical Processing: Removes residual monomers, solvents, and volatile byproducts from polymer synthesis, nanocomposite fabrication, and petrochemical analysis workflows at pilot and production scales.
3. Large-Volume Environmental Sample Processing: Prepares large-volume environmental samples (soil extracts, water concentrates, air filter extracts) by concentrating extracted pollutants and contaminants for GC-MS and HPLC analysis in environmental monitoring laboratories.
4. Cannabinoid and Hemp Extract Processing at Pilot Scale: Used for the large-scale concentration and purification of cannabinoid extracts from hemp and cannabis plants for commercial CBD product manufacturing and research.
5. Biopharmaceutical Process Development and Scale-Up: Used in the concentration of protein solutions, removal of process impurities, and purification of therapeutic biologics during process development and scale-up to pilot production .
6. Cosmetics Manufacturing and Quality Control at Pilot Scale: Used in the concentration of active cosmetic ingredients, removal of extraction solvents, and quality control testing of personal care products for commercial manufacturing .
7. Large-Scale Flavor and Fragrance Processing: Used for the concentration and purification of volatile flavor compounds and fragrance ingredients for commercial food and perfume manufacturing.
8. Veterinary Pharmaceutical Manufacturing at Scale: Supports the large-scale development and quality control of veterinary pharmaceuticals, including liquid formulations and injectable solutions for commercial production.
9. Pilot Plant and Scale-Up Support for Pharmaceutical R&D: Serves as a bridge between laboratory-scale R&D and full-scale production, enabling method transfer and process optimization for new drug formulations .
10. Industrial Quality Control of Chemicals and Solvents: Supports purity testing and quality assurance of industrial solvents, intermediates, and finished chemical products at pilot and production scales.
11. High-Throughput Solvent Removal in Contract Manufacturing Organizations (CMOs): Supports parallel synthesis and large-batch processing workflows in CMO facilities by providing efficient, reproducible solvent removal across multiple production runs.
12. Extraction of Bioactive Compounds from Marine Organisms at Scale: Used for the concentration and purification of bioactive compounds from marine sources for pharmaceutical and nutraceutical research and production.
13. Educational and Training Laboratories for Industrial Chemistry: Serves as an essential demonstration tool for teaching industrial-scale distillation, evaporation, and solvent recovery techniques in university chemical engineering programs.
14. Continuous Processing with Automatic Switching Valve Technology: Automatic switching valve enables continuous collection of distillate without breaking system vacuum, significantly increasing throughput for industrial applications .
15. Heating Bath with Teflon Coating for Easy Cleaning: Inner layer of the bath pot is made of Teflon coating, which is resistant to high and low temperatures, corrosion resistant, easy to clean, and avoids cross-contamination during the experimental process .
16. Special Heat Insulation Design for Operator Safety: Special insulation design keeps outer surface temperature low (pot shell surface temperature low), avoiding experimental personnel burns .
17. Continuous Feeding Capability: Solution can be continuously fed into evaporating flask without interrupting the distillation process, enabling extended production runs .
18. Digital Steam Temperature Sensing Device: Digital display steam temperature sensor provides real-time feedback of solvent steam temperature, allowing adjustment of appropriate vacuum degree for optimal distillation .
19. Optional Vacuum Controller Integration: Automation control with optional vacuum controller to control vacuum degree of samples and realize automatic solvent separation .
20. Forward and Reverse Rotation Function: Suitable for concentration of samples containing powder or solid particles, with reciprocation rotation function for optimal drying .
21. PTFE Sealing System: Professional sealing system design with PTFE sealing ring provides high temperature resistance, corrosion resistance, and durability for extended service life .
22. Double-Layer High-Efficiency Condenser: Double-layer high-efficiency condenser tube with large cooling area and anti-backflow design ensures strong evaporation capacity, efficient sample recovery from small to large quantities, and prevents evaporation condenser backflow .
23. Protected Glassware Option: Optional glassware with explosion-proof film available for enhanced operator safety .
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: A pilot-scale digital rotary evaporator (spinning and steaming machine) with 20L evaporating flask capacity, motorized lift, and large LCD display, designed for large-scale evaporation, concentration, and solvent recovery in pilot production, biopharmaceutical manufacturing, and industrial research laboratories .
  • Designation: RE2000-E Pilot Scale Digital Control Rotary Evaporator, RE2000-E Rotary Evaporator, DLAB RE2000-E, Pilot Scale Rotary Evaporator, 20L Rotary Evaporator, Pilot-Scale CNC Rotary Evaporator .
  • Key Components:
o Large LCD Digital Display: Shows heating temperature, rotation speed, forward/reverse direction, and time information for complete process control .
o Motorized Lift: Stepless automatic motor lifting of the heat bath with 180mm stroke; smooth, silent operation, and noise reduction .
o Water/Oil Heating Bath: Temperature range from 20-100°C for water bath and 20-180°C for optional oil bath; Teflon-coated inner layer; switchable water/oil heating modes .
o Double-Layer High-Efficiency Condenser: Large cooling area condenser with anti-backflow design; strong evaporation capacity ensures efficient sample recovery from small to large quantities .
o Evaporating Flask: 20L volume with continuous feeding capability .
o Receiving Flask: Standard receiving flask with automatic switching valve for continuous collection .
o Sealing System: Professional PTFE sealing ring with high temperature resistance, corrosion resistance, and durability .
o Automatic Switching Valve: Allows continuous collection without affecting system vacuum or solvent distillation .
o Teflon Coating: Inner layer of bath pot made of Teflon coating for corrosion resistance and easy cleaning .
o Optional Vacuum Controller: For automated control of vacuum degree .
o Protected Glassware: Optional glassware with explosion-proof film for enhanced safety .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Application: Suitable for pilot production, biotechnology, pharmaceutical manufacturing, chemical engineering, cosmetics, and food industry applications .
  • Evaporating Flask Volume: 20L .
  • Temperature Range: Water bath: 20-100°C; Oil bath: 20-180°C (optional) .
  • Temperature Control Accuracy: ±1°C .
  • Temperature Control Type: Microprocessor PID control .
  • Speed Range: 20-130 rpm .
  • Rotation Direction: Clockwise and counterclockwise (forward and reverse rotation) .
  • Evaporation Capacity: Max. 5.0 L/h (75% alcohol) .
  • Ultimate Vacuum: 9 mbar .
  • Heating Power: 4000W .
  • Total Power: 4000W .
  • Display: LCD (temperature/speed/forward-reverse/time) .
  • Timer: Yes; Time Setting Range: 0-999 minutes .
  • Lifting Mode: Motorized (automatic) .
  • Lifting Stroke: 180mm .
  • Motor Type: Lifting motor: DC brush motor; Rotating motor: high voltage brushless motor .
  • Dimensions (W × D × H): 900 × 490 × 1320 mm .
  • Weight: Not specified in search results.
  • Permissible Ambient Temperature: 5-40°C .
  • Permissible Ambient Humidity: ≤80% RH .
  • Protection Class: IP20 .
  • Heat Bath Capacity: 20L .
  • Safety Features: Motor overcurrent protection, earth leakage protection, dry heating protection (anti-dry burning), over-temperature protection function .
  • Special Features: Forward/reverse rotation function, continuous feeding capability, automatic switching valve, digital steam temperature sensor, optional vacuum controller, Teflon-coated bath, special insulation design .
  • Operating Voltage: 220V, 50/60Hz .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Construction: Floor-standing benchtop unit with durable construction; Teflon-coated heating bath for corrosion resistance and easy cleaning; special heat insulation design keeps outer surface temperature low to avoid operator burns .
  • Control System: Large LCD digital display with microprocessor PID temperature control; intuitive interface with multiple sets of data displayed on one screen; precise control and quick setting .
  • Heating Bath: 20L water/oil bath with switchable heating modes; Teflon-coated inner layer for corrosion resistance and easy cleaning; special heat insulation design keeps outer surface temperature low .
  • Glassware Compatibility: 20L evaporating flask with continuous feeding capability; compatible with full RE2000-E glassware series; optional glassware with explosion-proof film available .
  • Condenser Design: Double-layer high-efficiency condenser with large cooling surface area, strong evaporation capacity, and anti-backflow design to prevent backflow of evaporation condenser .
  • Rotation Control: Speed range 20-130 rpm; reversible direction (clockwise/counterclockwise) with forward/reverse function for concentration of samples containing powder or solid particles .
  • Sealing System: Professional PTFE sealing ring provides excellent chemical resistance, vacuum integrity, high temperature resistance, corrosion resistance, and durability .
  • Safety Features: Motor overcurrent protection, earth leakage protection, dry heating protection (anti-dry burning), over-temperature protection; automatic lift stop on power failure; special heat insulation design to prevent burns .
  • Continuous Collection: Automatic switching valve allows continuous collection without compromising system vacuum or solvent distillation, enabling uninterrupted processing for industrial applications .
  • Continuous Feeding: Solution can be continuously fed into evaporating flask without interrupting the distillation process .
  • Steam Temperature Monitoring: Digital display steam temperature sensor provides real-time feedback of solvent steam temperature, allowing adjustment of appropriate vacuum degree .
  • Optional Vacuum Control: Automation control with optional vacuum controller for sample vacuum degree control and automated solvent separation .
  • Flask Installation: Easy and quick installation of evaporating flask; continuous feeding capability for extended runs.
  • Data Management: LCD display with timer (0-999 minutes) for process documentation; real-time monitoring of temperature, speed, and direction .

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Pilot-scale laboratory equipment for manufacturing and quality control; essential support instrument for pharmaceutical production, bioprocessing, and industrial research laboratories .
  • Safety Features: Motor overcurrent protection, earth leakage protection (leakage protector), dry heating protection (anti-dry burning), over-temperature protection function, automatic lift stop on power failure, special heat insulation design to keep outer surface temperature low (avoiding operator burns) .
  • Chemical Resistance: Professional PTFE sealing ring provides excellent resistance to corrosive solvents, high temperature, and corrosion; Teflon-coated bath inner layer for corrosion resistance and easy cleaning .
  • Electrical Safety: Universal voltage compatibility (220V, 50/60Hz); grounded power connection required; IP20 protection class; 4000W power consumption .
  • Operational Safety: Special heat insulation design on heating bath prevents burns; motorized lift with overload protection; automatic lift on power failure; Teflon coating for chemical resistance; optional explosion-proof glassware available .
  • Environmental Compliance: Compatible with solvent recovery for waste reduction; supports sustainable manufacturing practices; energy-efficient design; uses standard industrial electrical supply.
  • Certification: Compliant with industrial safety standards; manufactured under quality management systems.

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store in clean, dry industrial laboratory environment; protect from dust and corrosive fumes when not in use; adequate space required due to footprint (900 × 490 × 1320mm) .
  • Cleaning: Clean glass components immediately after use with suitable solvent; drain heating bath after use; wipe exterior with damp cloth; Teflon coating allows easy cleaning without cross-contamination .
  • Glassware Care: Inspect 20L evaporating flask for cracks, chips, or stars before each use; never apply vacuum to damaged glassware; optional explosion-proof glassware available .
  • Seal Maintenance: Regularly inspect PTFE sealing ring for wear; replace if vacuum performance degrades .
  • Heating Bath Maintenance: Use appropriate bath media (water for RT-90°C, silicone oil for higher temperatures up to 180°C with optional oil bath); replace bath media regularly to prevent contamination; Teflon coating facilitates easy cleaning .
  • Calibration: Periodically verify temperature accuracy (±1°C) and rotation speed calibration (20-130 rpm) per industrial quality management protocols .
  • Vacuum Connection: Connect to appropriate industrial vacuum pump (external, not included) with compatible tubing; optional vacuum controller available for automated vacuum control .
  • Condenser Care: Clean double-layer condenser regularly to maintain cooling efficiency; anti-backflow design prevents backflow .
  • Power Requirements: Ensure adequate power supply (220V, 4000W) with proper grounding; dedicated circuit recommended .
  • Installation: Requires adequate clearance for operation and maintenance; floor-standing unit with 1320mm height; stable, level floor surface required .
6. LABORATORY & CLINICAL APPLICATIONS
  • Primary Application: Pilot-scale solvent removal, sample concentration, purification, and solvent recovery for pilot production, biopharmaceutical manufacturing, pharmaceutical production, chemical engineering, cosmetics manufacturing, and food industry quality control .
  • Clinical Role: Not used for direct patient diagnosis; serves as essential production equipment in pharmaceutical manufacturing, biopharmaceutical production, and industrial quality control settings where large-scale solvent evaporation and sample concentration are required for production of medications, diagnostics, and healthcare products .
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Glassware Integrity: Before use, inspect all glass components (20L evaporating flask, condenser) for cracks, chips, or stars; never apply vacuum to damaged glassware—implosion risk is severe at this scale.
  • Solvent Compatibility: Ensure solvents being evaporated are compatible with PTFE seals, Teflon coating, and glassware; use appropriate traps for corrosive or highly volatile substances; verify compatibility with pilot-scale processing requirements.
  • Bumping Hazard: Use anti-bump trap or bump guard between evaporation flask and condenser to prevent sample loss; pilot-scale bumping can cause significant product loss and safety hazards.
  • Heating Bath Media: Do not overfill heating bath; use water for temperatures up to 90°C, silicone oil for higher temperatures up to 180°C with optional oil bath; never leave heating bath on unattended during production runs.
  • Flask Securing: Ensure 20L evaporating flask is securely clamped before starting rotation; verify continuous feeding connections are properly sealed before operation.
  • Vacuum Release: Always release vacuum completely before removing receiving flask or evaporating flask to avoid implosion; use automatic switching valve for continuous collection without breaking vacuum .
  • Hot Surface Warning: Heating bath and glassware may be hot during operation; heating bath has special heat insulation design but surfaces still hot; allow to cool before handling .
  • Electrical Safety: Use properly grounded outlet; ensure voltage selector is correctly set for local supply (220V 50/60Hz); dedicated circuit recommended due to 4000W power draw .
  • Ventilation: Operate in well-ventilated industrial area or fume hood when evaporating volatile or hazardous solvents; adequate ventilation essential for pilot-scale solvent evaporation.
  • Lifting Safety: Use motorized lift (180mm stroke) for raising and lowering heating bath; do not attempt manual lifting; ensure lift overload protection is functional .
  • Heavy Equipment Handling: Unit requires careful handling during installation and relocation; use appropriate lifting equipment and team lifting protocols.
  • Training: Only trained industrial laboratory personnel and production staff should operate the RE2000-E for its intended manufacturing and quality control applications.

2. FIRST AID MEASURES

  • Hot Oil/Water Burn: If hot bath media contacts skin, cool affected area immediately with running water for at least 15 minutes; seek medical attention for severe burns; heating bath can reach 100°C (water) or 180°C (oil).
  • Chemical Splash: If large volume of solvent splashes into eyes, flush immediately with copious water for at least 15 minutes; seek immediate medical attention; use emergency eyewash station.
  • Glass Breakage/Cut: If 20L glassware breaks, evacuate area due to large volume of glass fragments and potential chemical spill; carefully collect fragments using forceps and heavy-duty gloves; dispose in sharps container; clean area thoroughly; seek medical attention for cuts.
  • Solvent Inhalation: If large volume of solvent vapors is inhaled, move to fresh air immediately; seek medical attention if respiratory distress occurs; activate ventilation systems.
  • Chemical Spill: If pilot-scale solvent spill occurs, evacuate area, activate emergency protocols, use appropriate chemical spill response equipment; contain spill to prevent environmental release.
  • Electrical Shock: If electrical shock occurs, disconnect power at main breaker immediately; seek medical attention for any electrical injury; do not touch victim with bare hands.

3. FIRE FIGHTING MEASURES

  • Flammability: Many common industrial solvents used with this instrument are highly flammable; equipment contains electrical components that are potential ignition sources; 20L solvent volumes present significant fire risk.
  • Extinguishing Media: Use carbon dioxide (CO₂) or dry chemical extinguisher for electrical or solvent fires; do not use water on electrical fires; Class B extinguishers for flammable liquids.
  • Fire Response: Immediately turn off unit and disconnect power supply using emergency shut-off; if pilot-scale solvent fire occurs, evacuate area immediately and sound alarm; never attempt to extinguish large industrial solvent fires alone; activate facility fire suppression systems.
  • Prevention: Maintain adequate ventilation to prevent solvent vapor accumulation; ground equipment to prevent static discharge; store flammable solvents away from ignition sources; follow facility hot work permit procedures.