High Speed Micro Centrifuge

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A High Speed Micro Centrifuge is a compact benchtop laboratory instrument designed for rapid separation of small-volume samples (0.2-2.0 mL) at speeds up to 30,000 RPM and RCF up to 65,000 x g. Available with fixed-angle or swinging-bucket rotors, digital controls, programmable protocols, imbalance detection, and safety lid lock. Refrigerated models maintain temperatures from -20°C to +40°C for temperature-sensitive applications. Primary clinical applications include DNA, RNA, and nucleic acid extraction for molecular diagnostics, protein precipitation and analysis for biochemistry, cell lysis and fractionation, microorganism and bacterial pelleting for microbiology, virus particle concentration, microvolume sample preparation for clinical chemistry, and rapid phase separation in extraction protocols. Essential equipment in molecular biology, clinical research, diagnostic laboratories, and biotechnology settings requiring rapid, efficient processing of small samples with high centrifugal forces.

Categories: LABORATORY EQUIPMENT AND SUPPLIES, Centrifuges and Separators, Lab Consumables Tags: Benchtop Centrifuge, DNA Extraction, High Speed Micro Centrifuge, Microcentrifuge, Molecular Biology Centrifuge, PCR Prep, Protein Precipitation, Refrigerated Centrifuge

Description

High Speed Micro Centrifuge

PRIMARY CLINICAL & DIAGNOSTIC USES

1. DNA, RNA, and Nucleic Acid Extraction:

Primary Use: High-speed micro centrifuges are essential for molecular biology protocols, spinning samples at high speeds to pellet nucleic acids during extraction and purification procedures for PCR, sequencing, and genetic testing applications.
How it helps: Enables scientists and clinicians to extract pure genetic material from cells, providing the foundation for tests that diagnose genetic disorders, identify infectious agents, and guide personalized cancer treatment.

2. Protein Precipitation and Analysis:

Primary Use: Used to pellet proteins and cellular debris during protein extraction, enabling purification of protein samples for Western blotting, ELISA, and other protein analysis techniques.
How it helps: Allows researchers to study the proteins that carry out the work of cells, helping them understand diseases at the molecular level and develop targeted therapies.

3. Cell Lysis and Fractionation:

Primary Use: Rapid centrifugation separates cellular components (nuclei, mitochondria, membranes) from lysed cells, enabling study of subcellular fractions in research and clinical applications.
How it helps: Lets scientists take cells apart to study their individual components, understanding how each part functions and what goes wrong in diseases that affect specific organelles.

4. Microorganism and Bacterial Pel letting:

Primary Use: Concentrates bacteria, yeast, and other microorganisms from liquid cultures or clinical specimens for downstream applications including Gram staining, culture, and molecular identification.
How it helps: Helps microbiology laboratories concentrate tiny amounts of bacteria from patient samples, making it easier to identify the organisms causing infections and determine the best antibiotics for treatment.

5. Phage Display and Virus Particle Concentration:

Primary Use: Used to pellet virus particles and bacteriophages from supernatants in virology research and diagnostic applications.
How it helps: Supports virology research and diagnostic testing by concentrating virus particles from large volumes, enabling their detection and study even when present in very small quantities.

6. Microvolume Sample Preparation:

Primary Use: Processes small volumes (0.2-2.0 mL) for various clinical laboratory applications including clinical chemistry, immunoassays, and specialized diagnostic testing.
How it helps: Makes it possible to perform dozens of different tests on tiny samples, which is especially important when working with precious patient samples or when only small volumes are available.

7. Rapid Phase Separation:

Primary Use: Separates aqueous and organic phases in extraction protocols (phenol-chloroform extractions) commonly used in molecular biology and clinical research.
How it helps: Quickly and cleanly separates different layers in extraction procedures, ensuring that researchers recover pure DNA, RNA, or proteins without contamination from organic solvents.

SECONDARY & SUPPORTIVE USES

1. Clinical Research Studies: Used in translational research laboratories for processing patient samples in studies of disease biomarkers and genetic variants, accelerating the translation of research discoveries into clinical practice.

2. Biotechnology and Pharmaceutical Development: Essential for drug discovery, vaccine development, and bioprocessing applications requiring rapid separation of small volumes, supporting the development of new therapies.

3. Forensic DNA Analysis: Used in forensic laboratories for DNA extraction from evidentiary samples including blood, saliva, and tissues, helping solve crimes and bring justice to victims.

4. Veterinary Diagnostic Testing: Processes samples for molecular and serological testing in veterinary medicine, helping veterinarians diagnose and treat illnesses in animals.

5. Environmental Microbiology Testing: Concentrates microorganisms from water and environmental samples for testing, monitoring environmental safety and public health.

6. Educational and Teaching Laboratories: Essential equipment for teaching molecular biology techniques in medical and graduate education, training the next generation of scientists and clinicians.

7. Quality Control in Food and Beverage Industry: Used for microbiological testing and quality assurance applications, ensuring food safety for consumers.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Compact, high-speed centrifuge designed for rapid separation of small-volume samples.
Common Names: Microcentrifuge, High-Speed Micro Centrifuge, Benchtop Microcentrifuge, Mini Centrifuge, High-G Microcentrifuge.
Rotor Types:
- Fixed-Angle Rotor: Most common; holds tubes at fixed angle (typically 45°); faster pelleting.
- Swinging-Bucket Rotor: Buckets swing out horizontally; for gradient separations and larger volumes.
Rotor Capacity: 12-24 × 1.5/2.0 mL microcentrifuge tubes; some models accept 0.2 mL PCR tubes and 0.5 mL tubes with adapters.
Maximum Speed: 12,000-30,000 RPM depending on model.
Maximum RCF: 10,000-65,000 x g.
Drive System: Brushless induction motor (most modern) for quiet, maintenance-free operation.
Display: Digital LCD or LED showing speed/RCF, time, and program status.
Controls: Touchpad or rotary knob for programming.
Timing: Digital timer from 1-99 minutes or continuous run; some models include short-spin function.
Program Memory: Stores multiple protocols for frequently used applications.
Temperature Control: Some models offer refrigeration (4°C to ambient) for temperature-sensitive samples.

2. TECHNICAL & PERFORMANCE PROPERTIES

Speed Range: 500-30,000 RPM depending on model.
RCF Range: Up to 65,000 x g (varies by rotor and speed).
Acceleration/Deceleration: Programmable rates for gentle or rapid separation.
Imbalance Detection: Automatic shutoff if load is unbalanced, protecting rotor and motor.
Lid Lock: Automatic locking during operation for safety; prevents opening while rotor spinning.
Noise Level: 45-65 dB depending on model and speed.
Cooling (Refrigerated Models): -20°C to +40°C for temperature-sensitive samples.
Short Spin Mode: Pulse function for quick spins.
Rotor Recognition: Automatic rotor identification for correct speed limits.
Power Requirements: 100-240 VAC, 50/60 Hz.

3. PHYSICAL & OPERATIONAL PROPERTIES

Dimensions: 20-40 cm × 25-45 cm × 15-30 cm (compact benchtop).
Weight: 10-30 kg depending on model and refrigeration.
Construction: Durable ABS plastic or steel exterior; stainless steel bowl interior.
Display: Digital LCD or LED with backlight.
Rotor Compatibility: Fixed-angle rotors (standard) or interchangeable rotors for different tube types.
Tube Types: 1.5 mL, 2.0 mL microcentrifuge tubes; 0.2 mL PCR tubes; 0.5 mL tubes with adapters.
Accessories: Tube adapters, rotor exchange tools, spare o-rings.
Certifications: Meets relevant safety and quality standards.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device (FDA, CE marked for IVD use when used with IVD applications).
Safety Standards: Complies with IEC 61010-2-020 for safety requirements for centrifuges.
Imbalance Detection: Automatic shutoff if load unbalanced, prevents damage and sample loss.
Lid Lock: Mechanical or electronic lock prevents opening while rotor spinning.
Emergency Lid Release: Manual release in case of power failure.
Over-speed Protection: Prevents operation above rotor's maximum rated speed.
Biohazard Safety: Sealed rotors or buckets available for infectious samples.
Quality Management: Manufactured under ISO 13485 or ISO 9001 certified processes.

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store in a clean, dry laboratory environment; avoid dust, humidity, and temperature extremes.
Installation: Place on rigid, level, non-flammable surface; ensure adequate ventilation.
Cleaning: Wipe exterior with mild detergent; disinfect with EPA-registered disinfectant if spills occur. Clean rotor and bowl per manufacturer instructions.
Rotor Care: Inspect regularly for corrosion or cracks; clean and dry after each use.
Calibration: Annual speed and temperature (refrigerated models) calibration verification recommended.
Maintenance: Regular preventive maintenance per manufacturer schedule.
Inspection: Before each use, inspect the rotor for cracks or damage; check lid lock function; verify balance.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Rapid separation of small-volume samples (0.2-2.0 mL) for molecular biology, biochemistry, and clinical diagnostic applications.
Typical Protocols:
- DNA/RNA Extraction: 12,000-16,000 x g for 1-10 minutes.
- Protein Precipitation: 10,000-20,000 x g for 5-15 minutes.
- Cell Pel letting: 1,000-5,000 x g for 3-10 minutes.
- Phase Separation: 12,000-16,000 x g for 5-10 minutes.
- Microorganism Concentration: 10,000-15,000 x g for 5-15 minutes.
Sample Compatibility:
- Standard Microcentrifuge Tubes: 1.5 mL, 2.0 mL.
- PCR Tubes/Strips: 0.2 mL (with adapters).
- Cryovials: Some models accommodate smaller cryogenic vials.
Limitations: Limited to small volumes; not suitable for large-volume clinical samples (e.g., 15 mL, 50 mL tubes).

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Balancing Loads: Always balance tubes by weight (not just number). Opposing tubes must have the same weight ±0.1-0.5 grams. Imbalance causes damage, inaccurate results, and potential injury.
Tube Compatibility: Use only tubes rated for the speed and RCF generated; tubes may explode if exceeded.
Rotor Inspection: Inspect rotors regularly for corrosion, cracks, or white deposits (aluminum corrosion). Replace immediately if damaged.
Overloading: Never exceed rotor's maximum rated speed or sample volume.
Biohazard Safety: Use sealed rotors or sealed tubes for infectious samples. Clean spills immediately.
Lid Lock: Never attempt to open the lid while is rotor spinning; wait for complete stop.
Temperature-Sensitive Samples: Use refrigerated model or pre-chill rotor for temperature-sensitive applications.
Training: Only trained personnel should operate centrifuges.
Chemical Resistance: Ensure tubes and rotors are compatible with chemicals used (organic solvents may damage plastics).

2. FIRST AID MEASURES

Tube Breakage During Run: Stop centrifuge immediately. Do not open the lid for 30 minutes to allow aerosol settling. Wear PPE and carefully remove broken tube fragments. Disinfect rotor and bowl thoroughly.
Chemical Spill: Follow chemical spill protocol; use appropriate PPE and absorbent materials.
Biohazard Spill: Contain with absorbent material; disinfect area with 10% bleach solution; dispose as biohazard waste.
Eye Contact with Contents: Flush eyes with copious water for 15 minutes; seek medical attention.
Electrical Malfunction: Disconnect power; do not use until serviced.

3. FIRE FIGHTING MEASURES

Flammability: Electrical components and plastic parts combustible.
Extinguishing Media: For electrical fire, use CO₂ or dry chemical (Class C) extinguisher; water may be used for surrounding materials.
Power Off: Disconnect power if safe to do so.

High Speed Micro Centrifuge

High Speed Micro Centrifuge

PRIMARY CLINICAL & DIAGNOSTIC USES

1. DNA, RNA, and Nucleic Acid Extraction:

Primary Use: High-speed micro centrifuges are essential for molecular biology protocols, spinning samples at high speeds to pellet nucleic acids during extraction and purification procedures for PCR, sequencing, and genetic testing applications.

How it helps: Enables scientists and clinicians to extract pure genetic material from cells, providing the foundation for tests that diagnose genetic disorders, identify infectious agents, and guide personalized cancer treatment.

2. Protein Precipitation and Analysis:

Primary Use: Used to pellet proteins and cellular debris during protein extraction, enabling purification of protein samples for Western blotting, ELISA, and other protein analysis techniques.

How it helps: Allows researchers to study the proteins that carry out the work of cells, helping them understand diseases at the molecular level and develop targeted therapies.

3. Cell Lysis and Fractionation:

Primary Use: Rapid centrifugation separates cellular components (nuclei, mitochondria, membranes) from lysed cells, enabling study of subcellular fractions in research and clinical applications.

How it helps: Lets scientists take cells apart to study their individual components, understanding how each part functions and what goes wrong in diseases that affect specific organelles.

4. Microorganism and Bacterial Pel letting:

Primary Use: Concentrates bacteria, yeast, and other microorganisms from liquid cultures or clinical specimens for downstream applications including Gram staining, culture, and molecular identification.

How it helps: Helps microbiology laboratories concentrate tiny amounts of bacteria from patient samples, making it easier to identify the organisms causing infections and determine the best antibiotics for treatment.

5. Phage Display and Virus Particle Concentration:

Primary Use: Used to pellet virus particles and bacteriophages from supernatants in virology research and diagnostic applications.

How it helps: Supports virology research and diagnostic testing by concentrating virus particles from large volumes, enabling their detection and study even when present in very small quantities.

6. Microvolume Sample Preparation:

Primary Use: Processes small volumes (0.2-2.0 mL) for various clinical laboratory applications including clinical chemistry, immunoassays, and specialized diagnostic testing.

How it helps: Makes it possible to perform dozens of different tests on tiny samples, which is especially important when working with precious patient samples or when only small volumes are available.

7. Rapid Phase Separation:

Primary Use: Separates aqueous and organic phases in extraction protocols (phenol-chloroform extractions) commonly used in molecular biology and clinical research.

How it helps: Quickly and cleanly separates different layers in extraction procedures, ensuring that researchers recover pure DNA, RNA, or proteins without contamination from organic solvents.

SECONDARY & SUPPORTIVE USES

1. Clinical Research Studies: Used in translational research laboratories for processing patient samples in studies of disease biomarkers and genetic variants, accelerating the translation of research discoveries into clinical practice.

2. Biotechnology and Pharmaceutical Development: Essential for drug discovery, vaccine development, and bioprocessing applications requiring rapid separation of small volumes, supporting the development of new therapies.

3. Forensic DNA Analysis: Used in forensic laboratories for DNA extraction from evidentiary samples including blood, saliva, and tissues, helping solve crimes and bring justice to victims.

4. Veterinary Diagnostic Testing: Processes samples for molecular and serological testing in veterinary medicine, helping veterinarians diagnose and treat illnesses in animals.

5. Environmental Microbiology Testing: Concentrates microorganisms from water and environmental samples for testing, monitoring environmental safety and public health.

6. Educational and Teaching Laboratories: Essential equipment for teaching molecular biology techniques in medical and graduate education, training the next generation of scientists and clinicians.

7. Quality Control in Food and Beverage Industry: Used for microbiological testing and quality assurance applications, ensuring food safety for consumers.

1. BASIC IDENTIFICATION ATTRIBUTES

Product Type: Compact, high-speed centrifuge designed for rapid separation of small-volume samples.

Common Names: Microcentrifuge, High-Speed Micro Centrifuge, Benchtop Microcentrifuge, Mini Centrifuge, High-G Microcentrifuge.

Rotor Types:

Fixed-Angle Rotor: Most common; holds tubes at fixed angle (typically 45°); faster pelleting.

Swinging-Bucket Rotor: Buckets swing out horizontally; for gradient separations and larger volumes.

Rotor Capacity: 12-24 × 1.5/2.0 mL microcentrifuge tubes; some models accept 0.2 mL PCR tubes and 0.5 mL tubes with adapters.

Maximum Speed: 12,000-30,000 RPM depending on model.

Maximum RCF: 10,000-65,000 x g.

Drive System: Brushless induction motor (most modern) for quiet, maintenance-free operation.

Display: Digital LCD or LED showing speed/RCF, time, and program status.

Controls: Touchpad or rotary knob for programming.

Timing: Digital timer from 1-99 minutes or continuous run; some models include short-spin function.

Program Memory: Stores multiple protocols for frequently used applications.

Temperature Control: Some models offer refrigeration (4°C to ambient) for temperature-sensitive samples.

2. TECHNICAL & PERFORMANCE PROPERTIES

Speed Range: 500-30,000 RPM depending on model.

RCF Range: Up to 65,000 x g (varies by rotor and speed).

Acceleration/Deceleration: Programmable rates for gentle or rapid separation.

Imbalance Detection: Automatic shutoff if load is unbalanced, protecting rotor and motor.

Lid Lock: Automatic locking during operation for safety; prevents opening while rotor spinning.

Noise Level: 45-65 dB depending on model and speed.

Cooling (Refrigerated Models): -20°C to +40°C for temperature-sensitive samples.

Short Spin Mode: Pulse function for quick spins.

Rotor Recognition: Automatic rotor identification for correct speed limits.

Power Requirements: 100-240 VAC, 50/60 Hz.

3. PHYSICAL & OPERATIONAL PROPERTIES

Dimensions: 20-40 cm × 25-45 cm × 15-30 cm (compact benchtop).

Weight: 10-30 kg depending on model and refrigeration.

Construction: Durable ABS plastic or steel exterior; stainless steel bowl interior.

Display: Digital LCD or LED with backlight.

Rotor Compatibility: Fixed-angle rotors (standard) or interchangeable rotors for different tube types.

Tube Types: 1.5 mL, 2.0 mL microcentrifuge tubes; 0.2 mL PCR tubes; 0.5 mL tubes with adapters.

Accessories: Tube adapters, rotor exchange tools, spare o-rings.

Certifications: Meets relevant safety and quality standards.

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device (FDA, CE marked for IVD use when used with IVD applications).

Safety Standards: Complies with IEC 61010-2-020 for safety requirements for centrifuges.

Imbalance Detection: Automatic shutoff if load unbalanced, prevents damage and sample loss.

Lid Lock: Mechanical or electronic lock prevents opening while rotor spinning.

Emergency Lid Release: Manual release in case of power failure.

Over-speed Protection: Prevents operation above rotor's maximum rated speed.

Biohazard Safety: Sealed rotors or buckets available for infectious samples.

Quality Management: Manufactured under ISO 13485 or ISO 9001 certified processes.

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store in a clean, dry laboratory environment; avoid dust, humidity, and temperature extremes.

Installation: Place on rigid, level, non-flammable surface; ensure adequate ventilation.

Cleaning: Wipe exterior with mild detergent; disinfect with EPA-registered disinfectant if spills occur. Clean rotor and bowl per manufacturer instructions.