High Speed Refrigerated Centrifuge (D1524R)

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The High Speed Refrigerated Centrifuge (D1524R) is a benchtop refrigerated microcentrifuge designed for temperature-sensitive sample processing in clinical diagnostic, molecular biology, and research laboratories. With a maximum speed of 15,000 rpm (up to 21,380 × g) and a temperature range of -20°C to 40°C, this centrifuge maintains sample integrity during high-speed runs—preventing protein denaturation, enzyme inactivation, and nucleic acid degradation .
The refrigerated centrifuge features a powerful R290 fluorine-free refrigerant compressor with pre-cooling function, reaching 4°C from room temperature in just 7 minutes . The standard AS24-2 bio-safe rotor accommodates 24 × 1.5/2.0 mL microcentrifuge tubes with 0.5 mL and 0.2 mL adapters, while optional rotors support 0.2 mL × 36, 0.5 mL × 36, PCR-8 strips × 4, 5 mL × 12, and 5 mL × 18 configurations .
For the clinical laboratory scientist and medical technologist, the D1524R facilitates serum and plasma separation for blood chemistry testing, coagulation studies, and lipid panels under refrigerated conditions. For the molecular biologist, it supports DNA/RNA extraction and purification, PCR sample preparation (spin-down of 0.2 mL PCR tubes and strip tubes), protein precipitation for biochemical assays, and cell pelleting for culture processing .
The centrifuge incorporates comprehensive safety features including dual door lock, over-speed detection, over-temperature detection, rotor imbalance detection alarm, and an internal diagnosis system . The three-layer sealed biosafety rotors prevent aerosol escape and cross-contamination, while the high-strength aluminum alloy rotors withstand repeated autoclave sterilization at 121°C .
With an LCD display, 9-level adjustable acceleration and deceleration, and up to 9 program storage capacity, the D1524R provides reliable, reproducible performance for temperature-controlled centrifugation supporting patient diagnosis, treatment monitoring, and research outcomes .
Description

High Speed Refrigerated Centrifuge (D1524R)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Temperature-Sensitive Sample Processing for Molecular Diagnostics
  • Primary Use: Provides a refrigerated benchtop centrifuge with a temperature range of -20°C to 40°C, enabling centrifugation of temperature-sensitive biological samples such as live cells, proteins, enzymes, and nucleic acids without thermal degradation .
  • How it helps: For the molecular biologist and clinical laboratory scientist, the refrigerated centrifuge maintains sample integrity during high-speed runs—preventing protein denaturation, enzyme inactivation, and RNA degradation that would otherwise compromise diagnostic accuracy. For the patient undergoing molecular testing, temperature-controlled sample processing ensures reliable results for PCR-based infectious disease testing, genetic analysis, and cancer biomarker detection.
2. High-Speed Blood Component Separation for Clinical Chemistry
  • Primary Use: Achieves maximum speeds of 15,000 rpm (21,380 × g) with a 24 x 1.5/2.0 mL rotor capacity, enabling rapid separation of whole blood into serum, plasma, and cellular components for comprehensive diagnostic testing .
  • How it helps: For the medical technologist and clinical chemist, the D1524R processes up to 24 samples simultaneously at high centrifugal forces—reducing turnaround time for blood chemistry panels, lipid profiles, and coagulation studies while maintaining sample quality through active refrigeration. For the patient, faster, reliable sample processing means receiving diagnostic results more quickly, enabling earlier diagnosis and treatment initiation.
3. PCR and Nucleic Acid Purification Workflows
  • Primary Use: Accommodates 0.2 mL PCR tubes, PCR 8-strip tubes, and standard microcentrifuge tubes, supporting spin-down, pelleting, and purification steps in DNA/RNA extraction and PCR setup protocols .
  • How it helps: For the molecular diagnostics specialist, the refrigerated centrifuge maintains cold chain integrity during nucleic acid purification—preventing RNA degradation and ensuring high-yield, high-purity DNA/RNA for downstream amplification. For the patient, reliable PCR sample preparation contributes to accurate diagnostic results for COVID-19, influenza, hepatitis, HPV, and other infectious diseases .
4. Cell and Bacterial Pellet Preparation
  • Primary Use: Generates sufficient centrifugal force (up to 21,380 × g) to pellet cells from culture media, bacterial suspensions, and cell homogenates for downstream analysis .
  • How it helps: For the clinical microbiologist and cell biologist, the refrigerated centrifuge enables efficient cell harvesting and fractionation while maintaining cell viability through temperature control—essential for cell-based assays, bacterial culture processing, and vaccine development workflows. For the patient, accurate cell processing supports diagnostic testing for bacterial infections, cancer cytology, and immunological disorders.

SECONDARY & SUPPORTIVE USES

1. Protein Precipitation and Purification: Used for antibody and protein precipitate separation, enzymatic test preparation, and protein purification workflows .
2. Lipoprotein and Lipid Panel Analysis: Supports sample preparation for lipid profiling and cholesterol fractionation in clinical chemistry.
3. Therapeutic Drug Monitoring: Used for plasma and serum preparation for therapeutic drug level monitoring and toxicology screening.
4. Coagulation Testing Preparation: Supports platelet-poor plasma preparation for coagulation studies and clotting factor analysis.
5. Enzymatic Assay Preparation: Used for enzyme reaction processing and cleanup in biochemical and clinical assays .
6. Microfiltration and Cell Separation: Supports micro-filtration protocols and cell separation applications requiring gentle, temperature-controlled centrifugation .
7. Removing Cell Debris from Homogenates: Used to clarify lysates and remove cellular debris from tissue homogenates .
8. Bacterial and Yeast Cell Fractionation: Supports microbial cell fractionation for protein and nucleic acid extraction .
9. Veterinary Diagnostic Laboratory: Processes blood, urine, and tissue samples for animal health testing.
10. Clinical and Veterinary Diagnostics: Used for routine diagnostic sample processing in hospital and reference laboratories .
11. Biotechnology and Microbiology Research: Supports research applications requiring reproducible, temperature-controlled centrifugation .
12. Research and Academic Laboratories: Used in university and research laboratory settings for molecular biology workflows .
13. PCR Microtubes and Strips: Specifically designed for PCR tube and PCR 8-strip rotor compatibility .
14. Blood and Urine Separation: Routine separation of blood components and urine sediment preparation .
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: A high-speed refrigerated benchtop microcentrifuge with active temperature control, designed for clinical diagnostic sample processing, molecular biology applications, and temperature-sensitive research workflows .
  • Designation: D1524R High Speed Refrigerated Centrifuge, D1524R Refrigerated Microcentrifuge, High-Speed Refrigerated Centrifuge, Laboratory Refrigerated Centrifuge, DLAB D1524R .
  • Key Components:
    • Rotor AS24-2: 24 x 1.5/2.0 mL bio-safe rotor with 0.5 mL and 0.2 mL adapters .
    • Optional Rotors: 0.2 mL × 36, 0.5 mL × 36, PCR-8 strips × 4, 5 mL × 12, 5 mL × 18 capacity .
    • Refrigeration System: R290 fluorine-free refrigerant compressor, pre-cooling function .
    • Motor: Brushless DC motor for high-speed, quiet operation .
    • Display: LCD display for speed, time, and temperature monitoring .
    • Safety Features: Dual door lock, over-speed detection, over-temperature detection, rotor imbalance detection .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Maximum Speed: 15,000 rpm (200-15,000 rpm, step: 100 rpm) .
  • Maximum RCF (Relative Centrifugal Force): 21,380 × g, step: 10 × g .
  • Temperature Setting Range: -20°C to 40°C .
  • Rotor Capacity (Standard): 24 × 1.5/2.0 mL tubes .
  • Additional Rotor Capacities: 0.5 mL × 36, 0.2 mL × 36, PCR-8 strips × 4, 5 mL × 12, 5 mL × 18 .
  • Run Time: 30 seconds - 99 minutes; HOLD (continuous running) .
  • Acceleration/Braking Time: 25 seconds up / 25 seconds down with 9 adjustable acceleration/deceleration levels .
  • Pre-cooling Time: 7 minutes from room temperature to 4°C .
  • Motor Type: Brushless DC motor .
  • Noise Level: ≤ 56 dB .
  • Power Requirements: Single phase, 200-240V, 50Hz, 500W .
  • Dimensions (W × D × H): 332 × 553 × 283 mm .
  • Weight: 30 kg .
  • Refrigerant: R290 fluorine-free refrigerant, low carbon and environmental protection .
  • Program Storage: Up to 9 program storage capacity .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Construction: High-strength aluminum alloy rotors with three-layer biosafety sealing technology; autoclavable at 121°C .
  • Refrigeration System: Static pre-cooling; compressor automatically starts when set temperature is below ambient .
  • Lid Design: Automatic magnetic door lock; can be closed with one finger .
  • Control: LCD display with touch button control; speed/RCF switchover function .
  • Operation Modes: Continuous operation; inching operation; sound alert at run completion .
  • Rotor Exchange: Tool-free rotor change system.
  • Cooling Maintenance: Lid automatically closes after centrifugation to maintain chamber temperature; external condensation tank prevents moisture accumulation .
  • Portability: Benchtop footprint with robust 30 kg construction for stability.

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Class II medical device (instrument classification) .
  • Safety Certifications: CE certified; meets international electrical safety standards.
  • Safety Features: Dual door lock, over-speed detection, over-temperature detection, rotor imbalance detection alarm, internal diagnosis system .
  • Biosafety Rotor: Three-layer sealed rotor for biosafety; prevents aerosol escape and cross-contamination .
  • Rotor Sterilization: High-strength aluminum alloy rotor withstands numerous high-temperature and high-pressure sterilization cycles (121°C autoclavable) .
  • Electrical Safety: Over-temperature protection with internal diagnosis system; wide voltage tolerance .
  • Environmental Compliance: R290 fluorine-free refrigerant (low carbon, environmentally friendly) .

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.
  • Cleaning: Wipe exterior with soft, damp cloth; use mild detergent if needed.
  • Rotor Maintenance: Remove and clean rotors with mild detergent; autoclave at 121°C for sterilization.
  • Inspection: Inspect rotors for cracks or damage before each use; replace if compromised.
  • Condensation Management: Empty external condensation tank periodically .
  • Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

  • Primary Application: Temperature-controlled sample processing for molecular diagnostics, PCR preparation, blood chemistry, protein purification, and cell culture in clinical diagnostic and research laboratories .
  • Clinical Role: Essential sample preparation equipment in clinical diagnostic laboratories, hospital laboratories, molecular diagnostics labs, blood banks, pathology laboratories, and research facilities requiring refrigerated centrifugation .
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Rotor Balancing: Ensure rotor is balanced with tubes of equal weight; imbalance will trigger automatic shutdown alarm .
  • Lid Security: Ensure lid is securely closed before operation; magnetic lock prevents operation with open lid .
  • Rotor Inspection: Inspect rotors for cracks or damage before each use; do not use damaged rotors.
  • Tube Compatibility: Use only tubes rated for centrifugation at high speeds (up to 21,380 × g) and refrigerated conditions.
  • Temperature Verification: Verify set temperature has been reached before loading temperature-sensitive samples.
  • Cleaning: Clean spills immediately; disinfect if biological materials are involved.
  • Ventilation: Place on stable, level surface; ensure adequate ventilation around refrigeration system.
  • Training: Only trained laboratory personnel should operate the centrifuge.

2. FIRST AID MEASURES

  • Tube Breakage: If tube breaks during operation, stop centrifuge immediately, allow rotor to stop fully, carefully remove fragments using forceps, disinfect rotor and chamber.
  • Sample Splash: If biological sample splashes, disinfect area immediately with appropriate disinfectant.
  • Imbalance Shutdown: If imbalance shutdown occurs, rebalance rotor equally, restart centrifuge.
  • Refrigerant Leak: If refrigerant leak is suspected, ventilate area immediately, disconnect power, contact service personnel.

3. FIRE FIGHTING MEASURES

  • Flammability: Plastic components are combustible; electrical components present fire risk; R290 refrigerant is moderately flammable .
  • Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
  • Fire Response: Unplug centrifuge immediately; do not use water on electrical fire; ventilate area if refrigerant leak is suspected.