High Speed Refrigerated Centrifuge (DG1616R)

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The High Speed Refrigerated Centrifuge (DG1616R) is a refrigerated, large-capacity benchtop centrifuge designed for temperature-controlled high-throughput sample processing in clinical diagnostic, molecular biology, pharmaceutical, and industrial research laboratories . With a maximum speed of 16,000 rpm (up to 28,621 × g) and maximum capacity of 4 × 400 mL (1.6 liters), this centrifuge provides the speed, capacity, and refrigeration needed for high-volume sample processing while protecting temperature-sensitive biological samples .
The active refrigeration system maintains sample temperatures from -10°C to 40°C, with a pre-cooling function that reaches 4°C in minutes—preventing protein denaturation, enzyme inactivation, and RNA degradation during high-speed runs . The DG1616R features a maintenance-free brushless DC motor, new upgraded touch UI interface for user-friendly operation, and automatic rotor identification for safety . The SR400 SOR swing-out rotor accommodates 4 × 400 mL tubes with snap-on bio-caps, handling tube sizes from 2 mL to 100 mL, while fixed-angle rotors are available for high-speed applications up to 16,000 rpm .
For the clinical laboratory scientist and medical technologist, the DG1616R facilitates serum and plasma separation for blood chemistry testing, coagulation studies, and lipid panels under refrigerated conditions . It supports platelet-poor plasma preparation for advanced coagulation analysis, nucleic acid extraction and purification for molecular diagnostics (preventing RNA degradation), protein precipitation for biochemical assays, and cell pelleting for culture processing while maintaining cell viability through temperature control. Additional applications include urinalysis, fecal sample processing, microbiology sample preparation, and pharmaceutical quality control testing .
The centrifuge incorporates comprehensive safety features including electronic magnetic door locking, automatic rotor identification, imbalance detection, and 3-layer sealed rotors that are fully autoclavable at 121°C for biosafety . With programmable run times (30 seconds to 99 hours), 9 acceleration and 9 deceleration profiles, up to 100 program storage capacity, and a robust 90 kg construction, the DG1616R provides reliable, temperature-controlled performance for routine laboratory workflows supporting patient diagnosis and treatment monitoring .
Description

High Speed Refrigerated Centrifuge (DG1616R)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Temperature-Controlled High-Capacity Blood and Biological Fluid Separation
  • Primary Use: Provides a refrigerated, large-capacity benchtop centrifuge with a maximum capacity of 4 × 400 mL (1.6 liters), enabling temperature-controlled separation of whole blood into serum, plasma, and cellular components for diagnostic laboratory analysis .
  • How it helps: For the medical technologist and clinical laboratory scientist, the DG1616R combines high-throughput capacity (1.6 liters) with active refrigeration to maintain sample integrity during processing—reducing hands-on time while protecting temperature-sensitive analytes. For the patient, faster high-volume sample processing with temperature control ensures reliable diagnostic results for cardiovascular disease, diabetes, and coagulation disorders.
2. Active Refrigeration for Temperature-Sensitive Sample Protection
  • Primary Use: Maintains sample temperatures from -10°C to 40°C, with a pre-cooling function that reaches 4°C in minutes—protecting temperature-sensitive biological samples such as proteins, enzymes, RNA, and cellular components during high-speed centrifugation .
  • How it helps: For the molecular biologist and clinical laboratory scientist, active refrigeration prevents protein denaturation, enzyme inactivation, and RNA degradation during high-speed runs—ensuring sample integrity for downstream molecular testing, protein assays, and diagnostic workflows. For the patient undergoing molecular diagnostic testing, temperature-controlled sample processing ensures reliable results for PCR-based infectious disease testing, genetic analysis, and cancer biomarker detection .
3. High-Speed Separation for Molecular Diagnostics and Research
  • Primary Use: Achieves maximum speeds of 16,000 rpm (up to 28,621 × g) with a brushless DC motor, enabling high-speed separation of subcellular organelles, precipitation of nucleic acids, and clarification of lysates for molecular biology workflows .
  • How it helps: For the molecular biologist and clinical laboratory scientist, the high centrifugal force combined with active refrigeration enables efficient separation of temperature-sensitive biomolecules—critical steps in DNA/RNA extraction, protein purification, and molecular diagnostic workflows. For the patient undergoing genetic testing or molecular diagnostics, reliable high-speed separation with thermal protection contributes to accurate test results that guide treatment decisions.
4. Clinical Chemistry and Coagulation Testing Sample Preparation
  • Primary Use: Supports serum, plasma, and platelet-poor plasma preparation for blood chemistry panels, lipid profiles, coagulation studies, and therapeutic drug monitoring in clinical pathology laboratories .
  • How it helps: For the clinical chemist and pathologist, the DG1616R’s wide rotor compatibility and precise speed control (300-16,000 rpm in 1 rpm increments) ensure optimal separation parameters for different sample types—improving test result accuracy and reducing repeat testing . For the patient, standardized sample processing with temperature protection reduces test variability and ensures reliable diagnostic results for conditions requiring temperature-sensitive analyte measurement.
5. Versatile Rotor System for Multiple Clinical Applications
  • Primary Use: Features a wide range of fixed-angle and swing-out rotors, with swing-out rotors accommodating 4 × 400 mL tubes (SR400 SOR) and 4 × 200 mL tubes (SR200 SOR), handling tube sizes from 2 mL to 100 mL including conical and round-bottom tubes .
  • How it helps: For the laboratory manager, the multiple rotor options eliminate the need for several dedicated centrifuges—allowing a single refrigerated instrument to handle blood tube processing, urine concentration, fecal sample preparation, and specialized research applications that require temperature control. For the patient, versatile equipment ensures that diagnostic testing can be performed efficiently across multiple test types without equipment delays or sample degradation.

SECONDARY & SUPPORTIVE USES

1. Serum and Plasma Separation for Blood Chemistry: Used for routine blood chemistry panels including liver function tests, renal function tests, electrolytes, and cardiac biomarkers with temperature protection.
2. Platelet-Rich Plasma (PRP) Preparation: Supports PRP preparation for regenerative medicine and therapeutic applications using refrigerated conditions to maintain platelet viability.
3. Lipoprotein and Lipid Panel Analysis: Used for lipid profiling, cholesterol fractionation, and lipoprotein separation for cardiovascular risk assessment under temperature-controlled conditions.
4. Nucleic Acid Extraction and Purification: Used in DNA and RNA extraction protocols for spin column-based purification in molecular diagnostics and research, preventing RNA degradation during centrifugation.
5. Protein Precipitation and Biochemical Assays: Used for antibody and protein precipitate separation, enzymatic test preparation, and protein purification workflows requiring cold temperatures.
6. Urinalysis and Body Fluid Concentration: Used for urine sediment preparation, cerebrospinal fluid concentration, and other body fluid sample processing with sample temperature protection.
7. Fecal Sample Processing for Occult Blood Testing: Used for fecal sample separation pre-processing in clinical laboratories .
8. Microbiology Sample Processing: Supports bacterial and yeast cell pelleting for culture preparation, antimicrobial susceptibility testing, and microbial identification with temperature control for viable organisms.
9. Cell Culture and Tissue Homogenate Processing: Used for pelleting cells from culture media and removing cellular debris from tissue homogenates at refrigerated temperatures to maintain cell viability.
10. Pharmaceutical Quality Control: Used in pharmaceutical QC laboratories for sample preparation, product testing, and stability studies requiring temperature control.
11. CRO Pharmaceutical Research: Supports sample separation in contract research organization workflows for drug development with refrigerated sample protection .
12. Biotechnology and Industrial Research: Supports cell harvesting, culture clarification, and product recovery in bioprocessing applications requiring cold centrifugation.
13. Research and Academic Laboratories: Used in university and research laboratory settings for routine centrifugation needs requiring temperature control.
14. Veterinary Diagnostic Laboratory: Supports sample processing for animal health testing and veterinary diagnostics with refrigerated sample protection.
15. Environmental and Water Quality Testing: Used for water sample analysis, pollutant detection, and environmental monitoring with temperature-sensitive sample protection .
16. Food and Beverage Industry Testing: Used for fat, protein, and foodborne microorganism separation in food safety and quality control laboratories.
17.  Automated and High-Throughput Laboratories: Suitable for integration into automated workflows with 100-program memory storage and HOLD mode for continuous runs .
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: A refrigerated, large-capacity high-speed benchtop centrifuge with 1.6 liter maximum capacity, designed for temperature-controlled clinical diagnostic sample processing, molecular biology applications, pharmaceutical research, and industrial laboratory use .
  • Designation: DG1616R High Speed Refrigerated Centrifuge, Refrigerated Large Capacity Centrifuge, High Speed Multi-Purpose Centrifuge, DLAB DG1616R, Temperature-Controlled Centrifuge .
  • Key Components:
    • SR400 SOR Swing-Out Rotor: 4 × 400 mL capacity with snap-on bio-caps, maximum speed 5,000 rpm, RCF 4,639 × g; handles 2 mL, 5 mL, 7 mL, 10 mL, 15 mL, c15 mL, 50 mL, c50 mL, and 100 mL tubes .
    • SR200 SOR Swing-Out Rotor: 4 × 200 mL capacity with snap-on bio-caps, maximum speed 5,500 rpm, RCF 5,495 × g .
    • Fixed-Angle Rotors: Available for high-speed applications up to 16,000 rpm.
    • Refrigeration System: Active compressor cooling with pre-cooling function (4°C in minutes) .
    • Control: New upgraded touch UI interface, user-friendly operation .
    • Safety Features: Electronic magnetic door locking system, automatic rotor identification, imbalance detection .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Maximum Speed: 16,000 rpm (300 – 16,000 rpm, step: 1 rpm) .
  • Maximum RCF (Relative Centrifugal Force): 28,621 × g (step: 1 × g) .
  • Maximum Capacity: 4 × 400 mL (1.6 liters) .
  • Temperature Setting Range: -10°C to 40°C, step: 1°C .
  • Pre-Cooling Function: Reaches 4°C from room temperature in minutes .
  • Speed Accuracy: ±20 rpm .
  • Temperature Accuracy: ±2.0°C .
  • Run Time: 30 seconds to 99 hours 59 minutes 59 seconds; HOLD (continuous running) .
  • Acceleration/Deceleration: Adjustable acceleration (9 speeds) and deceleration (9 speeds) .
  • Program Memory Storage: Up to 100 program storage capacity .
  • Motor Type: Maintenance-free brushless DC motor .
  • Noise Level: ≤ 70 dB .
  • Power Requirements: 100–240V, 50/60 Hz, 1050W .
  • Dimensions (L × W × H): 658 × 623 × 375 mm .
  • Weight: 90 kg .
  • Permissible Ambient Temperature and Humidity: 5–40°C, 80% RH .
  • Rotor Material: 3-layer sealed high-strength aluminum alloy rotors, fully autoclavable at 121°C .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Construction: Durable chassis engineered for high mechanical stability during 16,000 rpm operation; high-strength aluminum alloy rotors .
  • Refrigeration System: Active compressor cooling; dual temp-setting ensures rotor temperature reaches set point; lid automatically closes after centrifugation to maintain chamber temperature .
  • Control: New upgraded touch UI interface with full-color display; user-friendly operation for program selection and parameter adjustment .
  • Rotor Exchange: Tool-free rotor change system for quick switching between rotor types.
  • Rotor Identification: Automatic rotor identification for safety and performance optimization .
  • Lid Operation: Electronic magnetic door locking system; lid can be closed with one hand soft touch .
  • Operation Modes: Timed operation; HOLD (continuous operation) for extended runs .
  • Acceleration Profiles: 9 adjustable acceleration and 9 deceleration levels for gentle braking and optimal separation .
  • Portability: Benchtop footprint with robust 90 kg construction for stability.
  • Universal Voltage: 100-240V universal voltage allows worldwide operation without voltage conversion .

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Class II medical device meeting international safety standards.
  • Safety Certifications: CE and GLP-compliant operational standards ; manufactured under strict quality control procedures.
  • Safety Features: Electronic magnetic door locking system, automatic rotor identification, imbalance detection alarm, over-speed detection, lid safety interlock .
  • Biosafety Rotor: 3-layer sealed rotors ensure safe centrifugation and prevent aerosol escape; high-strength aluminum alloy, rotors can be fully autoclavable at 121°C .
  • Electrical Safety: Brushless DC motor with over-temperature protection; wide voltage tolerance (100-240V) .
  • Noise Control: Low noise operation (≤70 dB) for comfortable laboratory environment .
  • Refrigerant Compliance: Environmentally compliant refrigerant system.
  • Compliance: Manufactured under GLP-compliant quality control standards.

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation and power connection.
  • Cleaning: Wipe exterior with soft, damp cloth; use mild detergent if needed; clean rotor chamber after each use.
  • Rotor Maintenance: Remove and clean rotors with mild detergent; dry thoroughly before reinstallation; rotors are autoclavable at 121°C for sterilization.
  • Inspection: Inspect rotors for cracks or damage before each use; replace if compromised.
  • Refrigeration Check: Verify set temperature has been reached before loading temperature-sensitive samples.
  • Annual Calibration: Annual speed and temperature calibration recommended for critical applications.
  • Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

  • Primary Application: Temperature-controlled, high-capacity, high-speed sample processing for blood chemistry, molecular diagnostics, clinical pathology, pharmaceutical research, and industrial quality control .
  • Clinical Role: Essential sample preparation equipment in clinical diagnostic laboratories, hospital pathology departments, molecular diagnostics labs, blood banks, pharmaceutical QC laboratories, and industrial research facilities requiring refrigerated centrifugation .
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Rotor Balancing: Ensure rotor is balanced with tubes of equal weight; imbalance may cause excessive vibration and trigger automatic shutdown .
  • Rotor Compatibility: Verify rotor is compatible with the centrifuge; automatic rotor identification system helps ensure correct rotor use .
  • Lid Security: Ensure lid is securely closed before operation; electronic magnetic locking system prevents operation with open lid .
  • Rotor Inspection: Inspect rotors for cracks or damage before each use; do not use damaged rotors.
  • Tube Compatibility: Use only tubes rated for centrifugation at maximum speed (28,621 × g) and refrigerated conditions.
  • Rotor Loading: Load tubes symmetrically; never run rotor with unbalanced loads.
  • Temperature Verification: Verify set temperature has been reached before loading temperature-sensitive samples.
  • Cleaning: Clean spills immediately; disinfect rotor chamber if biological materials are involved.
  • Placement: Place on stable, level surface; ensure adequate ventilation around the refrigeration system.
  • Training: Only trained laboratory personnel should operate the centrifuge.

2. FIRST AID MEASURES

  • Tube Breakage: If tube breaks during operation, stop centrifuge immediately, allow rotor to stop fully, carefully remove fragments using forceps, disinfect rotor and chamber.
  • Sample Splash: If biological sample splashes, disinfect area immediately with appropriate disinfectant.
  • Imbalance Shutdown: If imbalance shutdown occurs, rebalance rotor equally, restart centrifuge.
  • Power Failure: If power fails during operation, allow rotor to stop naturally before opening lid.
  • Refrigerant Leak: If refrigerant leak is suspected, ventilate area immediately, disconnect power, contact service personnel.

3. FIRE FIGHTING MEASURES

  • Flammability: Plastic and aluminum components; electrical components present fire risk.
  • Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
  • Fire Response: Unplug centrifuge immediately; do not use water on electrical fire.