Intelligent Rotary Evaporator – Integrated (RE100-CV)

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The Intelligent Rotary Evaporator – Integrated (RE100-CV), space-saving distillation system that combines a heating bath, rotating motor, self-cooling metal condenser, and vacuum controller into a single benchtop unit . Designed for high-efficiency solvent removal, this unit features a large 7-inch LCD touch screen that allows for precise, synchronized control of rotation speed (20-280 rpm), heating temperature (RT to 180°C), and vacuum pressure (1-1000 mbar) . Its innovative self-cooling metal condenser can drop 40°C in 5 minutes, eliminating the need for an external chiller and reducing energy consumption by up to 50% compared to traditional models .

For the pharmaceutical researcher and petroleum chemist, the Intelligent Rotary Evaporator – Integrated (RE100-CV) facilitates critical sample preparation steps, including the concentration of heat-sensitive compounds, purification of active pharmaceutical ingredients (APIs), solvent recycling, and extraction of natural products . The motorized lift (150mm stroke) with power failure protection, together with a chemical-resistant double PTFE seal and a 220°C over-temperature protection, ensures high safety standards during automated distillation .

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Categories: LABORATORY EQUIPMENT AND SUPPLIES, Centrifuges and Separators Tags: DLAB Rotary Evaporator, Drug Development Support ., Integrated Rotary Evaporator, Pharmaceutical Lab Equipment, RE100-CV, RE100-CV Rotary Evaporator, Sample Concentration, Self-Cooling Condenser, Solvent Evaporation

Description

Intelligent Rotary Evaporator – Integrated (RE100-CV)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Solvent Removal and Sample Concentration for Drug Development

Primary Use: Provides an intelligent, integrated rotary evaporator with a built-in cooling system (eliminating the need for an external chiller) and self-cooling metal condenser that controls temperature from room temperature down to -40°C, designed for the efficient removal of solvents from chemical and biological samples in pharmaceutical research and quality control laboratories .
How it helps: For the pharmaceutical researcher and medicinal chemist, the Intelligent Rotary Evaporator – Integrated (RE100-CV) self-cooling condenser allows for rapid, efficient solvent evaporation without the need for external circulating water baths or dry ice . Its intelligent large 7-inch touchscreen provides precise control over vacuum, cooling temperature, rotation speed, and heating parameters, accelerating the drug purification and development process . For the patient, researchers can develop and test new medications more efficiently, potentially shortening the timeline for new treatments to reach clinical trials.

2. Purification of Natural Products for Quality Control

Primary Use: Used for the extraction, separation, and purification of natural products and active pharmaceutical ingredients (APIs), removing extraction solvents from botanical and biological samples under reduced pressure .
How it helps: For the analytical chemist and quality control specialist, the Intelligent Rotary Evaporator – Integrated (RE100-CV) integrated design and programmable favorites function (saving up to 5 common procedure files with up to 5 steps each) ensure standardized, reproducible purification workflows for batch-to-batch quality testing . For the patient, accurate quality control of natural health products and pharmaceutical ingredients ensures product safety, purity, and consistent therapeutic efficacy.

3. Concentration of Heat-Sensitive Biological Samples

Primary Use: Enables the gentle evaporation of solvents from heat-sensitive biological materials, including protein solutions, enzyme preparations, and botanical extracts, at low temperatures under reduced pressure .
How it helps: For the biochemist and life science researcher, the Intelligent Rotary Evaporator – Integrated (RE100-CV) ability to cool the condenser to -40°C and precise vacuum control (1-1000mbar) allows for the efficient removal of water or organic solvents without exposing delicate biomolecules to thermal degradation. For the patient, this supports the development of stable biologic drugs and accurate diagnostic reagents.

4. Formulation Development in Pharmaceutical Manufacturing

Primary Use: Supports pharmaceutical formulation development through the efficient removal of solvents during the preparation of drug formulations, including oral solutions, suspensions, and topical preparations .
How it helps: For the pharmaceutical formulation scientist, the Intelligent Rotary Evaporator – Integrated (RE100-CV) capacity to hold up to a 3L evaporation flask handles both laboratory-scale R&D and pilot-scale production batches, enabling method transfer from research to manufacturing. For the patient, this facilitates the rapid development and scale-up of new drug formulations, improving access to novel medications.

SECONDARY & SUPPORTIVE USES

1. Essential Oil and Flavor Extraction: Used for the hydrodistillation and solvent extraction of volatile essential oils and flavor compounds from plant materials in fragrance and food science research .

2. Environmental Sample Testing: Prepares environmental samples (soil, water, air filters) by concentrating extracted pollutants and contaminants for GC-MS and HPLC analysis in environmental monitoring laboratories .

3. Solvent Recycling and Laboratory Waste Reduction: Recovers and recycles high-purity solvents from laboratory waste streams, reducing operational costs and minimizing the environmental impact of hazardous chemical disposal.

4. Concentration of Heat-Labile Food Extracts: Concentrates fruit and vegetable juices, herbal extracts, and bioactive peptides for food science research and nutraceutical development without compromising flavor or nutritional integrity.

5. Material Science and Polymer Research: Removes residual monomers, solvents, and volatile byproducts from polymer synthesis and purification processes in materials science research.

6. Clinical Chemistry Research Support: Prepares and concentrates biological fluids (urine, plasma, serum) for the analysis of clinical biomarkers and metabolites in research settings.

7. Educational and Teaching Laboratories: Serves as an essential demonstration tool for teaching distillation, evaporation, and solvent recovery techniques in university chemistry and biochemistry laboratories.

8. Veterinary Drug Formulation Development: Supports the development and quality control of veterinary pharmaceuticals, including liquid formulations and injectable solutions.

9. Nutraceutical and Supplement Manufacturing: Used in the concentration and purification of active ingredients from natural sources for nutraceutical and dietary supplement development.

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: An intelligent, integrated rotary evaporator (spinning and steaming machine) with a built-in self-cooling condenser, designed for the efficient evaporation and recovery of solvents in pharmaceutical, chemical, and biotechnological research laboratories .
Designation: RE100-CV Intelligent Rotary Evaporator, RE100-CV / RE100-CV Integrated Rotary Evaporator, Control Type Integrated Rotary Evaporator, DLAB Rotary Evaporator, RE100-CV Series .
Key Components:
- Self-Cooling Metal Condenser: Chemically-resistant condensing coil with a large condensation area, capable of dropping 40°C in 5 minutes, eliminating the need for an external chiller .
- Heating Bath: Temperature range from room temperature to 180°C, capable of heating both oil and water, with 1300W heating power .
- Motor Lift: Motorized lift mechanism with a 150mm stroke, automatically raising the evaporation flask to a safe position after a power failure or timer completion .
- Control Interface: Large 7-inch LCD touch screen for full control of vacuum, cooling temperature, speed, heating temperature, and time .
- Vacuum Control: Built-in vacuum controller capable of controlling pressure from 1-1000 mbar .
- Sealing System: Dual stainless steel spring seal with a chemically resistant PTFE seal for superior performance .

2. TECHNICAL & PERFORMANCE PROPERTIES

Condenser Temperature Range: Room temperature to -40°C .
Condenser Cooling Rate: Achieves a 40°C temperature drop in 5 minutes .
Heating Temperature Range: Room temperature to 180°C .
Temperature Control Accuracy (Water): ±1°C .
Temperature Control Accuracy (Oil): ±3°C .
Rotation Speed Range: 20-280 rpm .
Rotation Direction: Forward and backward (clockwise and counterclockwise) .
Vacuum Control Range: 1-1000 mbar .
Evaporation Flask Capacity: Up to 3L .
Lifting Type: Motorized .
Lifting Stroke: 150mm .
Heating Power: 1300W .
Total Power: 3000W .
Refrigerant: R404a (non-toxic, non-polluting, and environmentally friendly).
Control Type: Integrated automatic control; program control with memory storage.
Time Setting Range: 1-999 minutes .
Number of Programs: Can store up to 5 common procedure files (each capable of a multi-step program) .
Power Supply: 100-120/200-240V, 50/60 Hz (universal voltage) .
Dimensions (L × W × H): 45.1 × 41.3 × 73.7 cm (451 × 413 × 737 mm) .
Weight: 54.4 kg .
Operating Temperature: 5-40°C .
Permissible Relative Humidity: ≤80% RH .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Fully integrated structural design with a built-in vacuum control system and cooling system, eliminating the need for external circulating water units and significantly reducing the instrument footprint .
Control System: A large 7-inch LCD touch screen allows for single-click simultaneous startup of the cooler, heating bath, vacuum controller, and rotation, or individual component control .
Data Monitoring: Real-time monitoring of running curves (vacuum, temperature, speed) is displayed during operation for full process control .
Intelligent Features: Favorites function can store up to 5 common procedure files; the system supports editing of settings for routine, repetitive workflows .
Safety Features: Contains a 220°C over-temperature protection and an automatic motor lift that raises the flask upon power failure or timer end .
Energy Efficiency: At set low temperatures, the unit can shut off the refrigeration cycle, reducing total energy consumption by approximately 50% compared to traditional systems .
Maintenance: No external cooling medium (e.g., water bath, ethylene glycol, dry ice) is required for standard operation, reducing maintenance complexity .
Ergonomics: Evacuated flask retreat structure for easy removal of the evaporation flask .

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Not a medical device; it is classified as standard laboratory equipment (Rotary Evaporator) . It is not registered for clinical diagnosis but is essential for pharmaceutical and analytical research and quality control.
Safety Features: Contains an automatic power-off and lift function upon power failure, a 220°C overheating protection , and a highly chemical-resistant sealing system to prevent hazardous solvent leaks .
Electrical Safety: Certified for use with universal voltage (100-120/200-240V) .
Environmental Compliance: Uses R404a refrigerant; integrated design drastically reduces solvent waste and uses no external cooling water .
Ingress Protection: Rated IP20 for protection against solid objects >12mm .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store under ambient laboratory conditions (5-40°C), with the glassware clean and dry. Keep the unit covered to protect from excessive dust.
Cleaning: All glass components should be cleaned immediately after use with a suitable solvent to remove residues. The heating bath should be drained of water or oil after use to prevent fouling.
Maintenance: Inspect the PTFE seal and vacuum grease regularly to maintain an optimal vacuum seal. Regularly inspect glassware for cracks or stars (stress points).
Installation: The unit is a fully integrated, heavy bench-top device (weighing 54.4 kg) and must be placed on a stable, level, chemically resistant work surface with adequate ventilation .

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Efficient solvent removal, sample concentration, and purification for drug discovery, natural product extraction, and chemical synthesis in pharmaceutical, biotech, and industrial laboratories .
Clinical Role: Not used for direct diagnosis. Plays a critical support role in clinical research, pharmaceutical quality control, and the development of new therapeutics.

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Glassware Integrity: Before use, inspect all glass components (evaporation and receiving flasks) for cracks, chips, or stars. Never apply vacuum to damaged glassware, as it may implode.
Solvent Compatibility: Ensure the solvent being evaporated is compatible with the PTFE seals and the metal condenser coils. Use appropriate traps for corrosive or highly volatile substances.
Bumping Hazard: Use an anti-bump trap or bump guard between the evaporation flask and the condenser to prevent sample loss or contamination due to sudden boiling.
Bath Media: Do not overfill the heating bath. Use appropriate media (water for RT-90°C, silicone oil for >90°C). Never leave the heating bath on unattended over long periods.
Glass Assembly: Ensure all glass joints are clean and lightly greased (where appropriate) to maintain a vacuum seal and prevent seizure. Ensure the flask is securely clamped.
Vacuum Release: Always release the vacuum completely before removing the receiving flask or evaporation flask to avoid implosion or spray back.
Cooling System: The self-cooling metal condenser operates at very low temperatures (-40°C); avoid direct skin contact during operation .
Training: Only trained laboratory personnel should operate the RE100-CV for its intended research and quality control applications.

2. FIRST AID MEASURES

Hot Oil/Water Burn: If hot bath media (oil/water) contacts skin, cool the affected area immediately with running water for at least 15 minutes. Seek medical attention for severe burns.
Cold Burn (Cryogenic Injury): If skin contacts the cold condenser (-40°C), warm the area gradually with lukewarm (not hot) water. Seek medical attention immediately if numbness or blistering occurs.
Chemical Splash: If solvent splashes into eyes, flush immediately with copious amounts of water for at least 15 minutes and seek immediate medical attention.

3. FIRE FIGHTING MEASURES

Flammability: Many common solvents used with this instrument are highly flammable. The equipment contains electrical components that are ignition sources.
Extinguishing Media: Use carbon dioxide (CO₂) or dry chemical extinguishers for electrical or solvent fires. Do not use water on electrical fires.
Fire Response: Immediately turn off the unit and disconnect the power supply. If a solvent fire breaks out inside the hood, evacuate the area and sound the alarm.

Intelligent Rotary Evaporator – Integrated (RE100-CV)

Intelligent Rotary Evaporator – Integrated (RE100-CV)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Solvent Removal and Sample Concentration for Drug Development

2. Purification of Natural Products for Quality Control

Primary Use: Used for the extraction, separation, and purification of natural products and active pharmaceutical ingredients (APIs), removing extraction solvents from botanical and biological samples under reduced pressure .

3. Concentration of Heat-Sensitive Biological Samples

Primary Use: Enables the gentle evaporation of solvents from heat-sensitive biological materials, including protein solutions, enzyme preparations, and botanical extracts, at low temperatures under reduced pressure .

4. Formulation Development in Pharmaceutical Manufacturing

Primary Use: Supports pharmaceutical formulation development through the efficient removal of solvents during the preparation of drug formulations, including oral solutions, suspensions, and topical preparations .

SECONDARY & SUPPORTIVE USES

1. Essential Oil and Flavor Extraction: Used for the hydrodistillation and solvent extraction of volatile essential oils and flavor compounds from plant materials in fragrance and food science research .

2. Environmental Sample Testing: Prepares environmental samples (soil, water, air filters) by concentrating extracted pollutants and contaminants for GC-MS and HPLC analysis in environmental monitoring laboratories .

3. Solvent Recycling and Laboratory Waste Reduction: Recovers and recycles high-purity solvents from laboratory waste streams, reducing operational costs and minimizing the environmental impact of hazardous chemical disposal.

4. Concentration of Heat-Labile Food Extracts: Concentrates fruit and vegetable juices, herbal extracts, and bioactive peptides for food science research and nutraceutical development without compromising flavor or nutritional integrity.

5. Material Science and Polymer Research: Removes residual monomers, solvents, and volatile byproducts from polymer synthesis and purification processes in materials science research.

6. Clinical Chemistry Research Support: Prepares and concentrates biological fluids (urine, plasma, serum) for the analysis of clinical biomarkers and metabolites in research settings.

7. Educational and Teaching Laboratories: Serves as an essential demonstration tool for teaching distillation, evaporation, and solvent recovery techniques in university chemistry and biochemistry laboratories.

8. Veterinary Drug Formulation Development: Supports the development and quality control of veterinary pharmaceuticals, including liquid formulations and injectable solutions.

9. Nutraceutical and Supplement Manufacturing: Used in the concentration and purification of active ingredients from natural sources for nutraceutical and dietary supplement development.

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: An intelligent, integrated rotary evaporator (spinning and steaming machine) with a built-in self-cooling condenser, designed for the efficient evaporation and recovery of solvents in pharmaceutical, chemical, and biotechnological research laboratories .

Designation: RE100-CV Intelligent Rotary Evaporator, RE100-CV / RE100-CV Integrated Rotary Evaporator, Control Type Integrated Rotary Evaporator, DLAB Rotary Evaporator, RE100-CV Series .

Key Components:

Self-Cooling Metal Condenser: Chemically-resistant condensing coil with a large condensation area, capable of dropping 40°C in 5 minutes, eliminating the need for an external chiller .

Heating Bath: Temperature range from room temperature to 180°C, capable of heating both oil and water, with 1300W heating power .

Motor Lift: Motorized lift mechanism with a 150mm stroke, automatically raising the evaporation flask to a safe position after a power failure or timer completion .

Control Interface: Large 7-inch LCD touch screen for full control of vacuum, cooling temperature, speed, heating temperature, and time .

Vacuum Control: Built-in vacuum controller capable of controlling pressure from 1-1000 mbar .

Sealing System: Dual stainless steel spring seal with a chemically resistant PTFE seal for superior performance .

2. TECHNICAL & PERFORMANCE PROPERTIES

Condenser Temperature Range: Room temperature to -40°C .

Condenser Cooling Rate: Achieves a 40°C temperature drop in 5 minutes .

Heating Temperature Range: Room temperature to 180°C .

Temperature Control Accuracy (Water): ±1°C .

Temperature Control Accuracy (Oil): ±3°C .

Rotation Speed Range: 20-280 rpm .

Rotation Direction: Forward and backward (clockwise and counterclockwise) .

Vacuum Control Range: 1-1000 mbar .

Evaporation Flask Capacity: Up to 3L .

Lifting Type: Motorized .

Lifting Stroke: 150mm .

Heating Power: 1300W .

Total Power: 3000W .

Refrigerant: R404a (non-toxic, non-polluting, and environmentally friendly).

Control Type: Integrated automatic control; program control with memory storage.

Time Setting Range: 1-999 minutes .

Number of Programs: Can store up to 5 common procedure files (each capable of a multi-step program) .

Power Supply: 100-120/200-240V, 50/60 Hz (universal voltage) .

Dimensions (L × W × H): 45.1 × 41.3 × 73.7 cm (451 × 413 × 737 mm) .

Weight: 54.4 kg .

Operating Temperature: 5-40°C .

Permissible Relative Humidity: ≤80% RH .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Fully integrated structural design with a built-in vacuum control system and cooling system, eliminating the need for external circulating water units and significantly reducing the instrument footprint .

Control System: A large 7-inch LCD touch screen allows for single-click simultaneous startup of the cooler, heating bath, vacuum controller, and rotation, or individual component control .

Data Monitoring: Real-time monitoring of running curves (vacuum, temperature, speed) is displayed during operation for full process control .

Intelligent Features: Favorites function can store up to 5 common procedure files; the system supports editing of settings for routine, repetitive workflows .

Safety Features: Contains a 220°C over-temperature protection and an automatic motor lift that raises the flask upon power failure or timer end .

Energy Efficiency: At set low temperatures, the unit can shut off the refrigeration cycle, reducing total energy consumption by approximately 50% compared to traditional systems .

Maintenance: No external cooling medium (e.g., water bath, ethylene glycol, dry ice) is required for standard operation, reducing maintenance complexity .

Ergonomics: Evacuated flask retreat structure for easy removal of the evaporation flask .

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Not a medical device; it is classified as standard laboratory equipment (Rotary Evaporator) . It is not registered for clinical diagnosis but is essential for pharmaceutical and analytical research and quality control.

Safety Features: Contains an automatic power-off and lift function upon power failure, a 220°C overheating protection , and a highly chemical-resistant sealing system to prevent hazardous solvent leaks .

Electrical Safety: Certified for use with universal voltage (100-120/200-240V) .

Environmental Compliance: Uses R404a refrigerant; integrated design drastically reduces solvent waste and uses no external cooling water .

Ingress Protection: Rated IP20 for protection against solid objects >12mm .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store under ambient laboratory conditions (5-40°C), with the glassware clean and dry. Keep the unit covered to protect from excessive dust.

Cleaning: All glass components should be cleaned immediately after use with a suitable solvent to remove residues. The heating bath should be drained of water or oil after use to prevent fouling.

Maintenance: Inspect the PTFE seal and vacuum grease regularly to maintain an optimal vacuum seal. Regularly inspect glassware for cracks or stars (stress points).

Installation: The unit is a fully integrated, heavy bench-top device (weighing 54.4 kg) and must be placed on a stable, level, chemically resistant work surface with adequate ventilation .

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: Efficient solvent removal, sample concentration, and purification for drug discovery, natural product extraction, and chemical synthesis in pharmaceutical, biotech, and industrial laboratories .

Clinical Role: Not used for direct diagnosis. Plays a critical support role in clinical research, pharmaceutical quality control, and the development of new therapeutics.

1. SAFETY PRECAUTIONS

Glassware Integrity: Before use, inspect all glass components (evaporation and receiving flasks) for cracks, chips, or stars. Never apply vacuum to damaged glassware, as it may implode.

Solvent Compatibility: Ensure the solvent being evaporated is compatible with the PTFE seals and the metal condenser coils. Use appropriate traps for corrosive or highly volatile substances.

Bumping Hazard: Use an anti-bump trap or bump guard between the evaporation flask and the condenser to prevent sample loss or contamination due to sudden boiling.