Low Speed Centrifuge
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A Low Speed Centrifuge is a benchtop or floor-standing laboratory instrument designed for routine separation of biological samples at speeds of 3,000-6,000 RPM and RCF up to 5,000 x g. Available with swinging-bucket or fixed-angle rotors accepting blood collection tubes (3-10 mL), 15 mL and 50 mL conical tubes, urine tubes, and microplates. Features include digital controls, programmable protocols, imbalance detection, safety lid lock, and refrigerated options (4°C to ambient). Primary clinical applications include serum/plasma separation for clinical chemistry, urine sediment preparation for microscopy, platelet-rich plasma (PRP) preparation for regenerative medicine, cytology and body fluid concentration, blood bank and transfusion applications, coagulation testing sample preparation, and microbiology specimen concentration. Essential equipment in clinical laboratories, hospital blood banks, and research facilities requiring gentle, efficient separation of routine clinical samples.
Description
Low Speed Centrifuge
PRIMARY CLINICAL & DIAGNOSTIC USES
1. Routine Blood Separation for Clinical Chemistry:
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Primary Use: Low speed centrifuges are essential for separating serum or plasma from whole blood samples by spinning at 3,000-4,000 RPM for 10-15 minutes, enabling analysis of biochemical parameters including glucose, electrolytes, liver enzymes, and renal function markers.
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How it helps: Transforms whole blood into the clear serum or plasma that automated chemistry analyzers need to run tests, providing doctors with critical information about organ function, metabolism, and overall health.
2. Urine Sediment Preparation for Microscopy:
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Primary Use: Used to concentrate cellular elements, casts, crystals, and microorganisms from urine specimens by centrifugation at 400-600 x g for 5-10 minutes, enabling microscopic examination for diagnosis of urinary tract infections and renal disorders.
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How it helps: Makes invisible problems visible by concentrating tiny particles in urine that would otherwise be too dilute to see, helping doctors identify kidney stones, infections, and other urinary tract conditions.
3. Platelet-Rich Plasma (PRP) Preparation:
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Primary Use: Employed in regenerative medicine and orthopedic practices to prepare PRP from patient’s own blood for therapeutic injections into joints, tendons, and soft tissues to promote healing.
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How it helps: Harnesses the body’s natural healing factors by concentrating platelets and their growth factors, offering patients a minimally invasive treatment option for chronic pain and injuries that may avoid the need for surgery.
4. Cytology and Body Fluid Concentration:
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Primary Use: Concentrates cells from ascitic fluid, pleural fluid, pericardial fluid, and cerebrospinal fluid for cytological examination to detect malignant cells or assess for infection.
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How it helps: Gives pathologists a richer sample to examine, improving the detection of cancer cells or infectious organisms in body fluids and helping doctors make earlier, more accurate diagnoses.
5. Blood Bank and Transfusion Applications:
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Primary Use: Used for preparing packed red blood cells, platelet concentrates, and for compatibility testing (cross-matching) by gently spinning blood samples to observe agglutination reactions.
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How it helps: Makes the most of every blood donation by separating whole blood into components that can help multiple patients, and ensures that when a patient needs blood, it is compatible and safe for transfusion.
6. Coagulation Testing Sample Preparation:
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Primary Use: Prepares platelet-poor plasma by centrifugation at 2,500-3,500 RPM for coagulation studies including PT, APTT, and fibrinogen testing.
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How it helps: Removes platelets and cellular debris that could interfere with coagulation testing, ensuring that patients on blood thinners or with bleeding disorders receive accurate test results.
7. Microbiology Specimen Concentration:
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Primary Use: Concentrates bacteria from body fluids (CSF, pleural fluid, synovial fluid) for culture and Gram stain, improving diagnostic yield in infectious disease testing.
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How it helps: Increases the chances of finding and identifying bacteria in difficult-to-diagnose infections, ensuring patients with serious conditions like meningitis or septic arthritis receive the right antibiotics quickly.
SECONDARY & SUPPORTIVE USES
1. Veterinary Diagnostics: Used in veterinary laboratories for processing blood, urine, and other specimens from animals, helping veterinarians diagnose and treat illnesses in pets and livestock with the same accuracy as human medicine.
2. Research and Clinical Trials: Essential for processing biological samples in research settings including cell culture, protein analysis, and drug development studies, supporting scientific discovery.
3. Fertility and Reproductive Medicine: Used to process semen samples for sperm count and motility analysis, helping couples achieve their dream of starting a family.
4. Food Safety and Quality Control: Used in food testing laboratories to concentrate pathogens from food samples, helping prevent foodborne illness outbreaks.
5. Pharmaceutical Quality Control: Employed in pharmaceutical manufacturing to test product stability and purity, ensuring medications are safe and effective.
6. Educational and Teaching Laboratories: Essential equipment in medical, nursing, and clinical laboratory science education programs, training future healthcare professionals.
7. Environmental Testing: Used to concentrate water samples for analysis of microorganisms or chemical contaminants, helping protect public health by ensuring drinking water is safe.
KEY PRODUCT FEATURES
1. BASIC IDENTIFICATION ATTRIBUTES
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Product Type: Benchtop or floor-standing centrifuge designed for routine separation of biological samples at lower speeds.
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Common Names: Low Speed Centrifuge, Clinical Centrifuge, Bench Centrifuge, Blood Bank Centrifuge, General Purpose Centrifuge.
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Rotor Types:
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Swinging-Bucket Rotor: Buckets swing out horizontally; ideal for blood collection tubes, urine tubes, and gradient separations.
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Fixed-Angle Rotor: Tubes held at fixed angle; faster pelting, for routine clinical applications.
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Rotor Capacity: 4-48 tubes per run depending on model and tube size.
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Maximum Speed: 3,000-6,000 RPM typical.
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Maximum RCF: 2,000-5,000 x g.
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Tube Compatibility: Accepts standard blood collection tubes (3-10 mL), 15 mL conical tubes, 50 mL conical tubes, and microtiter plates.
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Drive System: Brushless induction motor or carbon brush motor.
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Display: Digital LCD or LED showing speed, RCF, time, and program status.
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Controls: Touchpad or rotary knob for programming.
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Timing: Digital timer from 1-99 minutes or continuous run.
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Program Memory: Stores multiple protocols for frequently used applications.
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Temperature Control: Some models offer refrigeration (4°C to ambient) for temperature-sensitive samples.
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Acceleration/Deceleration: Programmable rates to prevent sample disturbance.
2. TECHNICAL & PERFORMANCE PROPERTIES
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Speed Range: 500-6,000 RPM depending on model.
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RCF Range: Up to 5,000 x g.
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Rotor Options:
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Swinging-Bucket: For blood collection tubes (various sizes), 15 mL, 50 mL conical tubes.
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Fixed-Angle: For higher RCF applications, smaller tubes.
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Microplate Rotor: For centrifuging microtiter plates.
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Capacity Examples:
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Blood Tubes (3-10 mL): 12-48 tubes.
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15 mL Conical: 12-32 tubes.
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50 mL Conical: 4-16 tubes.
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Microplates: 2-4 plates.
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Acceleration/Deceleration: Programmable rates for gentle or rapid separation.
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Imbalance Detection: Automatic shutoff if load is unbalanced, protecting rotor and motor.
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Lid Lock: Automatic locking during operation for safety; prevents opening while rotor spinning.
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Noise Level: 50-65 dB depending on model and speed.
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Cooling (Refrigerated Models): 4°C to ambient for temperature-sensitive samples.
3. PHYSICAL & OPERATIONAL PROPERTIES
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Dimensions: 40-70 cm × 50-80 cm × 30-50 cm (varies by model).
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Weight: 30-80 kg depending on model and refrigeration.
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Construction: Durable steel or ABS plastic exterior; stainless steel bowl interior.
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Display: Digital LCD or LED with backlight.
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Rotor Compatibility: Multiple rotor options for various tube types and applications.
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Tube Adapters: Available for different tube sizes within the same rotor.
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Accessories: Tube racks, rotor exchange tools, spare o-rings.
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Power Requirements: 100-240 VAC, 50/60 Hz.
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Certifications: Meets relevant safety and quality standards for medical devices.
4. SAFETY & COMPLIANCE ATTRIBUTES
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Regulatory Status: Class I medical device (FDA, CE marked for IVD use when used with IVD applications).
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Safety Standards: Complies with IEC 61010-2-020 for safety requirements for centrifuges.
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Imbalance Detection: Automatic shutoff if load unbalanced, prevents damage and inaccurate results.
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Lid Lock: Mechanical or electronic lock prevents opening while rotor spinning.
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Emergency Lid Release: Manual release in case of power failure.
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Over-speed Protection: Prevents operation above rotor's maximum rated speed.
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Biohazard Safety: Sealed rotors or buckets available for infectious samples.
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Quality Management: Manufactured under ISO 13485 or ISO 9001 certified processes.
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CE Mark: Complies with European safety and EMC requirements.
5. STORAGE & HANDLING ATTRIBUTES
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Storage: Store in clean, dry laboratory environment; avoid dust, humidity, and temperature extremes.
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Installation: Place on rigid, level, non-flammable surface; ensure adequate ventilation (especially refrigerated models).
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Cleaning: Wipe exterior with mild detergent; disinfect with EPA-registered disinfectant if spills occur. Clean rotor and bowl per manufacturer instructions.
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Rotor Care: Inspect regularly for corrosion or cracks; clean and dry after each use.
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Calibration: Annual speed and temperature (refrigerated models) calibration verification recommended.
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Maintenance: Regular preventive maintenance per manufacturer schedule (motor, brushes if applicable, refrigeration system).
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Inspection: Before each use, inspect the rotor for cracks or damage; check lid lock function; verify balance.
6. LABORATORY & CLINICAL APPLICATIONS
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Primary Application: Routine separation of biological samples for clinical chemistry, hematology, urinalysis, and blood banking applications.
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Typical Protocols:
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Serum/Plasma Separation: 3,000-4,000 RPM for 10-15 minutes.
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Urine Sediment: 400-600 x g for 5-10 minutes.
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PRP Preparation: 1,000-1,500 RPM for 10-15 minutes (specific protocols vary).
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Coagulation Plasma: 2,500-3,500 RPM for 10-15 minutes.
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Blood Bank Applications: 1,000-2,000 RPM for 5-10 minutes (gentle spinning).
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Sample Compatibility:
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Blood Collection Tubes: 3 mL, 5 mL, 7 mL, 10 mL (various brands).
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Conical Tubes: 15 mL, 50 mL.
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Urine Tubes: Standard urine collection containers with adapters.
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Microplates: 96-well, 384-well plates with appropriate rotor.
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RCF Calculation: RCF = 1.118 × 10⁻⁵ × r × RPM² (r = radius in cm).
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Limitations: Lower maximum RCF than high-speed centrifuges; not suitable for molecular biology applications requiring >5,000 x g.
SAFETY HANDLING PRECAUTIONS
1. SAFETY PRECAUTIONS
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Balancing Loads: Always balance tubes by weight (not just number). Opposing tubes must have the same weight ±0.5-1.0 grams. Imbalance causes damage, inaccurate results, and potential injury.
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Tube Compatibility: Use only tubes rated for the speed and RCF generated; tubes may break if exceeded.
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Rotor Inspection: Inspect rotors regularly for corrosion, cracks, or white deposits (aluminum corrosion). Replace immediately if damaged.
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Overloading: Never exceed rotor's maximum rated speed or sample volume.
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Biohazard Safety: Use sealed rotors or buckets for infectious samples (blood, body fluids). Clean spills immediately.
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Lid Lock: Never attempt to open the lid while the rotor is spinning; wait for complete stop.
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Temperature-Sensitive Samples: Use refrigerated model or allow samples to reach appropriate temperature before centrifugation.
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Training: Only trained personnel should operate centrifuges.
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Chemical Resistance: Ensure tubes and rotors are compatible with chemicals used (acids, organics may damage rotors).
2. FIRST AID MEASURES
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Tube Breakage During Run: Stop centrifuge immediately. Do not open the lid for 30 minutes to allow aerosol settling. Wear PPE and carefully remove broken tube fragments. Disinfect rotor and bowl thoroughly.
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Chemical Spill: Follow chemical spill protocol; use appropriate PPE and absorbent materials.
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Biohazard Spill: Contain with absorbent material; disinfect area with 10% bleach solution; dispose as biohazard waste.
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Eye Contact with Contents: Flush eyes with copious water for 15 minutes; seek medical attention.
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Electrical Malfunction: Disconnect power; do not use until serviced.
3. FIRE FIGHTING MEASURES
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Flammability: Electrical components and plastic parts combustible.
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Extinguishing Media: For electrical fire, use CO₂ or dry chemical (Class C) extinguisher; water may be used for surrounding materials.
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Power Off: Disconnect power if safe to do so.

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