Digital Dry Bath Dual Block (HB150-S2)

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The Digital Dry BathDual Block (HB150-S2) is a compact benchtop dry thermostat with extended high-temperature capability up to 150°C and dual independent heating blocks, designed for high-throughput advanced molecular biology applications, thermostable enzyme inactivation, and high-temperature diagnostic assay preparation in clinical and research laboratories . With a temperature range from room temperature +5°C to 150°C and temperature control accuracy of ±0.3°C (25-90°C) and ±0.6°C (90-150°C), this dry bath provides consistent, uniform heating across two independently controlled blocks for protocols requiring extreme temperatures up to 150°C .

The HB150-S2 features a microprocessor-controlled system with independent LED displays and control knobs for each block, allowing simultaneous processing of protocols requiring different elevated temperatures (e.g., 95°C for DNA denaturation on block one, 120°C for thermostable enzyme inactivation on block two, 150°C for specialized high-temperature applications) . The dual independent block operation saves valuable bench space while doubling throughput compared to single-block units .

The unit accepts various optional interchangeable aluminum heating blocks for different tube formats including 0.2mL, 0.5mL, 1.5/2mL, 5mL, 15mL, and 50mL tubes . Each block has an independent heat-preserving lid that prevents contamination and ensures temperature stability . A sound reminder function alerts users when set temperature is reached and at run completion for each block .

For the molecular biologist and clinical laboratory scientist, the HB150-S2 supports complete heat inactivation of thermostable restriction enzymes and heat-labile enzymes (preventing interference with downstream diagnostic assays), protein denaturation for SDS-PAGE and Western blotting at elevated temperatures, DNA denaturation for GC-rich templates and challenging PCR protocols, and high-throughput sample preparation for specialized diagnostic workflows .

For the patient undergoing specialized molecular testing, the HB150-S2’s extended temperature capability (up to 150°C) combined with independent dual-block operation ensures complete inactivation of even thermostable enzymes, thorough DNA denaturation for the most challenging templates, and efficient processing of diverse high-temperature protocols—supporting accurate diagnostic results for complex genetic conditions, infectious diseases, and oncology testing that require extreme temperature control with high-throughput capacity.

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Categories: LABORATORY EQUIPMENT AND SUPPLIES, Incubators and Ovens Tags: Clinical Laboratory Equipment, DLAB HB150-S2, DNA Denaturation, Dual Block Dry Bath, GC-Rich PCR, HB150-S2 Digital Dry Bath, High-Temperature Dry Bath, High-Throughput Molecular Diagnostics, LED Digital Dry Bath, Thermostable Enzyme Inactivation

Description

Digital Dry Bath Dual Block (HB150-S2)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. High-Throughput High-Temperature Incubation for Advanced Molecular Diagnostics

Primary Use: Provides a dual-block digital dry bath with extended temperature range from room temperature +5°C to 150°C, enabling simultaneous high-temperature incubation for specialized molecular biology protocols, thermostable enzyme inactivation, and demanding diagnostic assay preparation .
How it helps: For the molecular biologist and clinical laboratory scientist, the HB150-S2 delivers precise temperature control (accuracy ±0.3°C at 25-90°C and ±0.6°C at 90-150°C) across two independent heating blocks with LED displays and user-friendly knob adjustment—allowing different assays requiring different elevated temperatures to be run concurrently. For the patient, access to extended temperature capabilities with high-throughput capacity ensures that specialized diagnostic assays can be processed efficiently, reducing referral delays and accelerating diagnosis.

2. Complete Thermostable Enzyme Inactivation at Elevated Temperatures

Primary Use: Used for complete heat inactivation of thermostable enzymes, restriction enzymes, and proteins requiring temperatures up to 150°C for irreversible denaturation, with independent block operation allowing different inactivation protocols simultaneously .
How it helps: For the clinical chemist and molecular biologist, the HB150-S2’s extended temperature range (up to 150°C) ensures complete, irreversible inactivation of even highly thermostable enzymes that may interfere with downstream diagnostic assays—improving assay specificity and reducing false-positive results. For the patient, thorough enzyme inactivation prevents erroneous test results that could lead to misdiagnosis or inappropriate treatment.

3. DNA Denaturation for GC-Rich and Challenging Templates

Primary Use: Provides controlled high-temperature heating for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows requiring stringent denaturation conditions for GC-rich or secondary structure-prone templates .
How it helps: For the molecular biologist, the HB150-S2’s precise temperature control (up to 150°C) and excellent temperature uniformity (±0.2°C at 37°C) ensures complete separation of double-stranded DNA even for the most challenging GC-rich templates—critical for PCR, sequencing, and hybridization-based assays where incomplete denaturation leads to failed reactions. For the patient, this supports accurate genetic testing for challenging templates and complex genomic regions.

4. Concurrent Multi-Temperature High-Temperature Workflows

Primary Use: The dual-block design allows independent temperature setting for each block, enabling simultaneous processing of protocols requiring different elevated temperatures (e.g., 95°C for DNA denaturation on block one, 120°C for thermostable enzyme inactivation on block two, 150°C for specialized high-temperature applications) .
How it helps: For the laboratory manager and clinical scientist, the ability to run multiple high-temperature protocols concurrently on a single instrument saves valuable bench space, reduces equipment costs, and streamlines complex diagnostic workflows that historically required multiple separate instruments . For the patient, consolidated equipment and parallel processing reduce sample handling time and accelerate result reporting.

SECONDARY & SUPPORTIVE USES

1. Restriction Enzyme Heat Inactivation for Thermostable Enzymes: Used for complete inactivation of thermostable restriction enzymes after DNA digestion with independent block operation for different temperatures.

2. Protein Purification and Western Blotting: Supports protein denaturation steps at elevated temperatures for SDS-PAGE sample preparation across multiple samples or protocols .

3. Nucleic Acid Extraction from Difficult Samples: Provides heating for cell lysis and protein digestion steps in DNA/RNA extraction from tissue or difficult sample types requiring elevated temperatures.

4. ELISA and Immunoassay High-Temperature Incubation: Supports specialized ELISA protocols requiring elevated temperature incubation with simultaneous processing of multiple assay conditions.

5. Lipid and Cholesterol Analysis: Used for heating samples in lipid profiling and cholesterol fractionation protocols requiring elevated temperatures.

6. Histology and Pathology Tissue Processing: Used for warming embedding media and specialized processing solutions requiring higher temperatures.

7. Pharmaceutical Quality Control Stability Testing: Supports stability testing of pharmaceutical products at elevated temperatures with independent block control.

8. Research and Academic Laboratories: Supports specialized research applications requiring incubation above 120°C with high-throughput capacity.

9. Veterinary Diagnostic Laboratory: Supports specialized testing protocols requiring high-temperature incubation for multiple sample types.

10. Clinical Chemistry Specialized Assays: Used for assays requiring elevated temperatures beyond standard incubation ranges with simultaneous processing.

11. Standard Molecular Biology Incubation: Routine incubation for enzyme reactions, ligations, and other standard molecular biology protocols on either block .

12. High-Throughput Molecular Diagnostics: Parallel processing of multiple patient samples or multiple assay types requiring elevated temperatures .

13. Heat-Preserving Lids: Independent block lids for each block prevent heat loss, ensure temperature stability, and prevent contamination .

14. Overheating Protection: Independent safety cutoff for each block for equipment and sample protection .

KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: A dual-block digital dry bath with extended high-temperature capability (up to 150°C), designed for high-throughput advanced molecular biology applications, thermostable enzyme inactivation, and high-temperature diagnostic assay preparation .
Designation: HB150-S2 Digital Dry Bath, Dual-Block Dry Bath, High-Temperature Dry Bath, LED Digital Dry Bath, DLAB HB150-S2 .
Key Components:
- Dual Heating Blocks: Two independent interchangeable aluminum blocks compatible with various tube sizes and formats .
- Microprocessor Controller: Regulates temperature independently for each block with automatic feedback for precise control up to 150°C .
- Dual LED Displays: Independent digital displays for real-time temperature and time monitoring for each block .
- Independent Control Knobs: User-friendly setting knobs for each block for simple, independent operation .
- Insulated Lids: Independent block lids for each block for heat preservation, temperature stability, and contamination prevention .
- External Sensor Ports: PT1000 temperature sensor connection capability for sample temperature verification (per block or shared) .

2. TECHNICAL & PERFORMANCE PROPERTIES

Temperature Range: Room temperature +5°C to 150°C (both blocks) .
Temperature Setting Range: 25°C to 150°C .
Temperature Control Accuracy: ±0.3°C (25-90°C); ±0.6°C (90-150°C) .
Temperature Uniformity @37°C: ±0.2°C .
Temperature Display Accuracy: 0.1°C .
Time Setting Range: 0 minutes to 99 hours 59 minutes (independent per block) .
Work Mode: Timed operation or continuous operation (independent per block) .
Heating Power: 100W per block (total 200W) .
Voltage/Frequency: 110/220V, 50/60Hz .
Display: Dual independent LED digital displays .
Sound Reminder: Yes, at temperature stabilization and run completion (per block) .
Safety Cut-off: Independent overheating protection per block .
Dimensions (W × D × H): 290 × 210 × 120 mm .
Weight: 3.2 kg (without blocks) .
Permissible Ambient Temperature: 10-40°C .
Permissible Ambient Humidity: <80% RH .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Durable outer housing designed for extended temperature operation up to 150°C; dual-block configuration for high-throughput benchtop processing .
Control System: Microprocessor-controlled with independent LED digital displays and independent control knobs for each block .
Operation Modes: Timing mode (0-99h59min) and continuous operation mode (independent per block) .
Independent Operation: Each block can be set to different temperatures and different run times simultaneously .
Block Compatibility: Accepts various optional interchangeable aluminum heating blocks for different tube formats (0.2mL, 0.5mL, 1.5/2mL, 5mL, 15mL, 50mL) .
Block Lids: Independent lids for each block for heat preservation, temperature stability, and contamination prevention .
Data Export: USB interface for traceability and quality records .
Sound Reminder: Audible alert per block at temperature stabilization and run completion .
Safety Features: Independent overheating protection per block .

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device for clinical diagnostic use .
Safety Features: Independent overheating protection per block, heat-preserving lids for contamination prevention .
High-Temperature Safety: Extended safety margins for 150°C operation; design ensures safe handling at extreme temperatures for both blocks .
Electrical Safety: Universal voltage (110/220V, 50/60Hz); 200W total power consumption .
Quality Compliance: USB data export supports GLP documentation and quality management .
Independent Operation Safety: Each block operates independently; failure of one block does not affect the other .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.
Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.
Block Maintenance: Remove and clean heating blocks independently with mild detergent; dry thoroughly before reinstallation.
Inspection: Inspect each block's contacts for residue or damage before each use; clean if needed.
Lid Use: Always use lids during operation to maintain temperature stability and prevent contamination .
Calibration: Use external PT1000 sensor periodically to verify sample temperature accuracy on critical block .
Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: High-throughput advanced molecular diagnostics requiring extended temperature capability (up to 150°C), including thermostable enzyme inactivation, DNA denaturation for GC-rich templates, and high-temperature sample preparation in clinical and research laboratories .
Clinical Role: Essential specialized sample preparation equipment in molecular diagnostics laboratories, reference laboratories, research facilities, and accredited clinical laboratories requiring extended temperature capabilities for challenging assays with high-throughput demands.

SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

Temperature Setting: Do not exceed recommended temperatures for specific sample types; excessive heat may denature proteins or degrade analytes; use caution when setting temperatures above 100°C on either block .
Block Installation: Ensure both heating blocks are properly seated before operation.
Temperature Verification: Allow each block to reach set temperature before loading temperature-sensitive samples; verify temperature stability before use .
Lid Use: Always use lids during operation to maintain temperature stability and prevent contamination; use caution—lids will be hot at high temperatures .
Hot Surface Warning: Surfaces may become very hot during extended operation at temperatures above 100°C; use caution when handling .
Independent Operation: Ensure that samples requiring different temperatures are loaded into the correct block .
Cleaning: Clean spills immediately; disinfect heating blocks if biological materials are involved; allow blocks to cool completely before removal .
Placement: Place on firm, flat, level, heat-resistant surface; ensure adequate clearance around unit for ventilation .
Training: Only trained laboratory personnel should operate the HB150-S2 for clinical diagnostic applications .

2. FIRST AID MEASURES

Burn/Scald: If hot heating block or surface contacts skin, cool affected area immediately with cool running water for at least 15 minutes; seek medical attention for severe burns .
Sample Spillage: If biological sample spills into unit, disconnect power, allow to cool completely, disinfect area immediately with 70% ethanol or appropriate disinfectant.
Electrical Malfunction: If unit shows signs of electrical malfunction, disconnect power immediately; do not attempt to operate; contact service personnel.
Calibration Verification: If test results are inconsistent, verify calibration using external PT1000 sensor before proceeding with diagnostic testing .

3. FIRE FIGHTING MEASURES

Flammability: Plastic housing and electrical components may burn.
Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
Fire Response: Unplug unit immediately; do not use water on electrical fire.

Digital Dry Bath Dual Block (HB150-S2)

Digital Dry Bath Dual Block (HB150-S2)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. High-Throughput High-Temperature Incubation for Advanced Molecular Diagnostics

Primary Use: Provides a dual-block digital dry bath with extended temperature range from room temperature +5°C to 150°C, enabling simultaneous high-temperature incubation for specialized molecular biology protocols, thermostable enzyme inactivation, and demanding diagnostic assay preparation .

2. Complete Thermostable Enzyme Inactivation at Elevated Temperatures

Primary Use: Used for complete heat inactivation of thermostable enzymes, restriction enzymes, and proteins requiring temperatures up to 150°C for irreversible denaturation, with independent block operation allowing different inactivation protocols simultaneously .

3. DNA Denaturation for GC-Rich and Challenging Templates

Primary Use: Provides controlled high-temperature heating for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows requiring stringent denaturation conditions for GC-rich or secondary structure-prone templates .

4. Concurrent Multi-Temperature High-Temperature Workflows

SECONDARY & SUPPORTIVE USES

1. Restriction Enzyme Heat Inactivation for Thermostable Enzymes: Used for complete inactivation of thermostable restriction enzymes after DNA digestion with independent block operation for different temperatures.

2. Protein Purification and Western Blotting: Supports protein denaturation steps at elevated temperatures for SDS-PAGE sample preparation across multiple samples or protocols .

3. Nucleic Acid Extraction from Difficult Samples: Provides heating for cell lysis and protein digestion steps in DNA/RNA extraction from tissue or difficult sample types requiring elevated temperatures.

4. ELISA and Immunoassay High-Temperature Incubation: Supports specialized ELISA protocols requiring elevated temperature incubation with simultaneous processing of multiple assay conditions.

5. Lipid and Cholesterol Analysis: Used for heating samples in lipid profiling and cholesterol fractionation protocols requiring elevated temperatures.

6. Histology and Pathology Tissue Processing: Used for warming embedding media and specialized processing solutions requiring higher temperatures.

7. Pharmaceutical Quality Control Stability Testing: Supports stability testing of pharmaceutical products at elevated temperatures with independent block control.

8. Research and Academic Laboratories: Supports specialized research applications requiring incubation above 120°C with high-throughput capacity.

9. Veterinary Diagnostic Laboratory: Supports specialized testing protocols requiring high-temperature incubation for multiple sample types.

10. Clinical Chemistry Specialized Assays: Used for assays requiring elevated temperatures beyond standard incubation ranges with simultaneous processing.

11. Standard Molecular Biology Incubation: Routine incubation for enzyme reactions, ligations, and other standard molecular biology protocols on either block .

12. High-Throughput Molecular Diagnostics: Parallel processing of multiple patient samples or multiple assay types requiring elevated temperatures .

13. Heat-Preserving Lids: Independent block lids for each block prevent heat loss, ensure temperature stability, and prevent contamination .

14. Overheating Protection: Independent safety cutoff for each block for equipment and sample protection .

1. BASIC IDENTIFICATION ATTRIBUTES

Device Type: A dual-block digital dry bath with extended high-temperature capability (up to 150°C), designed for high-throughput advanced molecular biology applications, thermostable enzyme inactivation, and high-temperature diagnostic assay preparation .

Designation: HB150-S2 Digital Dry Bath, Dual-Block Dry Bath, High-Temperature Dry Bath, LED Digital Dry Bath, DLAB HB150-S2 .

Key Components:

Dual Heating Blocks: Two independent interchangeable aluminum blocks compatible with various tube sizes and formats .

Microprocessor Controller: Regulates temperature independently for each block with automatic feedback for precise control up to 150°C .

Dual LED Displays: Independent digital displays for real-time temperature and time monitoring for each block .

Independent Control Knobs: User-friendly setting knobs for each block for simple, independent operation .

Insulated Lids: Independent block lids for each block for heat preservation, temperature stability, and contamination prevention .

External Sensor Ports: PT1000 temperature sensor connection capability for sample temperature verification (per block or shared) .

2. TECHNICAL & PERFORMANCE PROPERTIES

Temperature Range: Room temperature +5°C to 150°C (both blocks) .

Temperature Setting Range: 25°C to 150°C .

Temperature Control Accuracy: ±0.3°C (25-90°C); ±0.6°C (90-150°C) .

Temperature Uniformity @37°C: ±0.2°C .

Temperature Display Accuracy: 0.1°C .

Time Setting Range: 0 minutes to 99 hours 59 minutes (independent per block) .

Work Mode: Timed operation or continuous operation (independent per block) .

Heating Power: 100W per block (total 200W) .

Voltage/Frequency: 110/220V, 50/60Hz .

Display: Dual independent LED digital displays .

Sound Reminder: Yes, at temperature stabilization and run completion (per block) .

Safety Cut-off: Independent overheating protection per block .

Dimensions (W × D × H): 290 × 210 × 120 mm .

Weight: 3.2 kg (without blocks) .

Permissible Ambient Temperature: 10-40°C .

Permissible Ambient Humidity: <80% RH .

3. PHYSICAL & OPERATIONAL PROPERTIES

Construction: Durable outer housing designed for extended temperature operation up to 150°C; dual-block configuration for high-throughput benchtop processing .

Control System: Microprocessor-controlled with independent LED digital displays and independent control knobs for each block .

Operation Modes: Timing mode (0-99h59min) and continuous operation mode (independent per block) .

Independent Operation: Each block can be set to different temperatures and different run times simultaneously .

Block Compatibility: Accepts various optional interchangeable aluminum heating blocks for different tube formats (0.2mL, 0.5mL, 1.5/2mL, 5mL, 15mL, 50mL) .

Block Lids: Independent lids for each block for heat preservation, temperature stability, and contamination prevention .

Data Export: USB interface for traceability and quality records .

Sound Reminder: Audible alert per block at temperature stabilization and run completion .

Safety Features: Independent overheating protection per block .

4. SAFETY & COMPLIANCE ATTRIBUTES

Regulatory Status: Class I medical device for clinical diagnostic use .

Safety Features: Independent overheating protection per block, heat-preserving lids for contamination prevention .

High-Temperature Safety: Extended safety margins for 150°C operation; design ensures safe handling at extreme temperatures for both blocks .

Electrical Safety: Universal voltage (110/220V, 50/60Hz); 200W total power consumption .

Quality Compliance: USB data export supports GLP documentation and quality management .

Independent Operation Safety: Each block operates independently; failure of one block does not affect the other .

5. STORAGE & HANDLING ATTRIBUTES

Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.

Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.

Block Maintenance: Remove and clean heating blocks independently with mild detergent; dry thoroughly before reinstallation.

Inspection: Inspect each block's contacts for residue or damage before each use; clean if needed.

Lid Use: Always use lids during operation to maintain temperature stability and prevent contamination .

Calibration: Use external PT1000 sensor periodically to verify sample temperature accuracy on critical block .

Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

Primary Application: High-throughput advanced molecular diagnostics requiring extended temperature capability (up to 150°C), including thermostable enzyme inactivation, DNA denaturation for GC-rich templates, and high-temperature sample preparation in clinical and research laboratories .

Clinical Role: Essential specialized sample preparation equipment in molecular diagnostics laboratories, reference laboratories, research facilities, and accredited clinical laboratories requiring extended temperature capabilities for challenging assays with high-throughput demands.