Mini Dry Bath (MiniHC 100)
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The Mini Dry Bath (MiniHC 100) is a compact, lightweight (≤1 kg), and portable digital dry bath (mini incubator) with both heating and cooling capabilities (0°C to 100°C), designed for precise temperature-controlled sample preparation in clinical diagnostics, molecular biology, and point-of-care applications . With a temperature control accuracy of ±0.5°C, maximum heating rate of 8°C/min, and maximum cooling rate of 3°C/min, this palm-sized instrument provides reliable thermal performance for a wide range of diagnostic and research workflows .
The MiniHC 100 features a microprocessor-controlled system with LCD display for real-time monitoring, programmable memory supporting up to 9 programs (2 steps each for sequential temperature protocols), built-in user recalibration function for long-term accuracy, USB interface for data export and traceability, and error code display for troubleshooting . Overheating protection ensures safe and stable operation .
The device accepts interchangeable aluminum heating blocks compatible with various tube formats including 0.2mL (40 wells), 0.5mL (24 wells), 1.5mL/2mL (15 wells), 5mL, 15mL, and 50mL tubes, allowing flexibility for different sample types and volumes . The dual power options (100-240V AC for laboratory use; DC12V for field or vehicle use) support use in space-constrained laboratories, point-of-care testing sites, mobile laboratories, and field research stations .
For the clinical laboratory scientist and molecular biologist, the MiniHC 100 supports DNA denaturation for PCR preparation, nucleic acid amplification, enzyme-substrate reactions for clinical chemistry, enzyme preservation (cooling function), serum coagulation studies, electrophoresis gel degeneration, and sample warming for coagulation testing .
For the patient undergoing diagnostic testing for infectious diseases, genetic conditions, or metabolic disorders, the MiniHC 100’s precise temperature control (±0.5°C accuracy), rapid heating and cooling rates, and user calibration support ensure consistent sample preparation, reliable enzymatic assay results, and accurate nucleic acid extraction—supporting reliable test results that guide appropriate treatment decisions across clinical chemistry, molecular diagnostics, and point-of-care testing applications .
Description
Mini Dry Bath (MiniHC 100)
PRIMARY CLINICAL & DIAGNOSTIC USES
1. Heating and Cooling for Temperature-Sensitive Molecular Diagnostics
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Primary Use: Provides a compact, lightweight digital mini dry bath with both heating (up to 100°C) and cooling (down to 0°C) functions, designed for precise temperature control of clinical and molecular biology samples in diagnostic laboratory workflows .
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How it helps: For the clinical laboratory scientist and molecular biologist, the MiniHC 100 delivers precise temperature control (accuracy ±0.5°C) with rapid heating (8°C/min) and controlled cooling (3°C/min) capabilities—enabling both high-temperature denaturation and low-temperature sample preservation in a single compact instrument . For the patient, this integrated heating and cooling capability reduces processing time and minimizes the risk of sample degradation between different temperature protocols.
2. Nucleic Acid Amplification and DNA Denaturation for PCR Preparation
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Primary Use: Used for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows requiring precise temperature control (0-100°C) .
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How it helps: For the molecular biologist, the MiniHC 100’s precise temperature control (±0.5°C) and rapid heating rate (8°C/min) ensures consistent denaturation of double-stranded DNA—critical for PCR, sequencing, and hybridization-based assays used in infectious disease testing and genetic screening . For the patient undergoing genetic testing or infectious disease diagnosis, reliable denaturation supports accurate PCR results that guide appropriate treatment decisions.
3. Enzyme-Substrate Reactions and Biochemical Assays
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Primary Use: Provides stable temperature-controlled incubation for enzyme-substrate reactions, restriction enzyme digestions, and other biochemical assays used in clinical diagnostics .
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How it helps: For the clinical chemist, the MiniHC 100’s uniform temperature distribution (±0.5°C accuracy) ensures optimal reaction kinetics for enzymatic assays—critical for accurate liver function tests (ALT, AST), cardiac biomarkers, and metabolic panels. For the patient, reliable enzymatic assay results enable accurate diagnosis of myocardial infarction, hepatitis, and metabolic disorders.
4. Enzyme Preservation and Sample Cooling
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Primary Use: The active cooling function (down to 0°C) enables preservation of heat-sensitive enzymes, proteins, and reagents during experimental workflows, preventing thermal degradation .
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How it helps: For the molecular biologist and laboratory scientist, the MiniHC 100’s cooling capability maintains samples at 0-4°C before and after processing—preserving enzyme activity and nucleic acid integrity for downstream applications. For the patient, proper sample preservation ensures accurate diagnostic results and reduces the need for repeat specimen collection due to degraded samples.
SECONDARY & SUPPORTIVE USES
1. DNA Amplification and Electrophoresis Gel Degeneration: Used for sample preparation in DNA amplification protocols and electrophoresis gel denaturation steps for molecular diagnostics .
2. Serum Coagulation and Clinical Chemistry: Supports serum coagulation studies and clinical chemistry sample preparation requiring precise temperature control .
3. ELISA and Immunoassay Incubation: Provides precise temperature control for enzyme-linked immunosorbent assay (ELISA) incubation steps in infectious disease and autoimmune testing.
4. Protein Denaturation and Purification: Used for protein denaturation steps in Western blotting and protein purification workflows.
5. Nucleic Acid Extraction and Purification: Supports heating and cooling steps in spin column-based DNA/RNA extraction protocols for molecular diagnostics.
6. Lipid and Cholesterol Analysis: Used for warming and cooling samples in lipid profiling and cholesterol fractionation protocols.
7. Endocrine and Hormone Assay Preparation: Supports temperature-controlled incubation for thyroid function tests, reproductive hormone panels, and endocrine assays.
8. Coagulation Testing Sample Warming: Used for warming plasma samples and reagents for PT (Prothrombin Time) and PTT (Partial Thromboplastin Time) coagulation studies.
9. Therapeutic Drug Monitoring: Used for sample preparation in therapeutic drug monitoring and toxicology screening with controlled temperature.
10. Microbiology Culture Media Warming: Warms culture media to specified temperatures before inoculation in clinical microbiology workflows.
11. Blood Bank and Transfusion Medicine: Supports temperature-controlled processing of blood components and compatibility testing samples.
12. Bedside and Point-of-Care Testing: Portable design with DC12V power option allows use in point-of-care settings and mobile laboratories .
13. Field and Remote Laboratory Applications: Lightweight (≤1 kg) and compact design (110x162x140mm) supports use in field research stations and remote diagnostic applications .
14. Veterinary Diagnostic Laboratory: Supports clinical chemistry and molecular biology workflows for animal health testing.
15. Research and Academic Laboratories: Supports general laboratory sample preparation requiring both heating and cooling capabilities.
16. Quality Control Sample Preparation: Used for temperature-controlled preparation of QC samples for clinical laboratory quality assurance programs.
17. Programmable Multi-Step Protocols: Supports 9 program memory slots (2 steps each) for complex sample preparation workflows requiring sequential temperature settings .
18. USB Data Export for Documentation: USB interface allows data export for traceability and quality management records .
19. Temperature Self-Calibration: Built-in user recalibration function ensures long-term temperature accuracy for quality management compliance .
20. Error Code Display: Provides error code indication for troubleshooting and quality assurance .
KEY PRODUCT FEATURES
1. BASIC IDENTIFICATION ATTRIBUTES
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Device Type: A compact, lightweight digital mini dry bath (mini incubator) with both heating and cooling functions, LCD display, and programmable memory, designed for precise temperature-controlled sample preparation in clinical diagnostics, molecular biology, and research laboratories .
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Designation: MiniHC 100 Mini Dry Bath, Mini Dry Bath Incubator, Digital Dry Bath, MiniHC100, DLAB MiniHC100, Portable Dry Bath, Heating and Cooling Dry Bath .
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Key Components:
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Heating/Cooling Block: Interchangeable aluminum heating blocks compatible with various tube sizes (0.2mL, 0.5mL, 1.5mL, 2mL, 5mL, 15mL, 50mL) .
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LCD Display: Digital display for real-time temperature and time monitoring .
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Program Memory: 9 program slots (2 steps each) for sequential temperature protocols .
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Temperature Self-Calibration: Built-in user recalibration function for long-term accuracy .
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USB Interface: Data export for traceability and quality records .
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Error Code Display: Troubleshooting and error indication .
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2. TECHNICAL & PERFORMANCE PROPERTIES
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Functions: Heating and cooling (integrated) .
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Temperature Range: 0°C to 100°C .
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Temperature Setting Range: Room temperature -23°C to 100°C .
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Temperature Control Accuracy: ±0.5°C .
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Temperature Display Accuracy: 0.1°C .
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Maximum Heating Rate: 8°C/min .
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Maximum Cooling Rate: 3°C/min .
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Minimum Heating Time (25°C to 100°C): ≤20 minutes .
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Minimum Cooling Time (20°C to 0°C): ≤25 minutes .
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Time Setting Range: 0-999 minutes / 0-999 seconds .
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Program Memory: 9 programs (2 steps each) .
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Temperature Self-Calibration: Supported (built-in user recalibration) .
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USB Interface: Supported for data export .
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Error Code Display: Supported .
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Power: 60W .
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Display: LCD .
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Voltage/Frequency: 100-240V, 50/60Hz or DC12V .
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Dimensions (W × D × H): 110 × 162 × 140 mm .
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Weight: ≤1 kg .
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Permissible Ambient Temperature: +10°C to 40°C .
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Permissible Ambient Humidity: <80% RH .
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Overheating Protection: Yes .
3. PHYSICAL & OPERATIONAL PROPERTIES
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Construction: Compact, lightweight, palm-sized benchtop housing (110 × 162 × 140 mm) weighing ≤1 kg for easy portability and space-saving benchtop placement .
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Control System: Microprocessor-controlled with LCD digital display for real-time monitoring of temperature and time settings .
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Operation Modes: Timed operation (0-999 minutes/seconds) and continuous operation; programmable memory supports up to 9 programs (2 steps each) for multi-stage temperature protocols .
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Block Compatibility: Accepts various interchangeable aluminum heating blocks for tube formats including 0.2mL (40 wells), 0.5mL (24 wells), 1.5mL/2mL (15 wells), 5mL (6 wells), 15mL (4 wells), and 50mL (2 wells) tubes .
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Calibration: Built-in user recalibration function for long-term temperature accuracy; supports quality management compliance .
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Data Export: USB interface supports data export for traceability and quality records .
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Safety Features: Overheating protection with automatic shutdown for sample and user safety; error code display for troubleshooting .
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Power Options: Dual power options (100-240V AC for laboratory use; DC12V for field, vehicle, or point-of-care use) .
4. SAFETY & COMPLIANCE ATTRIBUTES
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Regulatory Status: Class I medical device for clinical diagnostic use; compliant with laboratory safety standards .
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Safety Features: Overheating protection (automatic shutdown), PID temperature control for stable operation, error code display for troubleshooting .
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Electrical Safety: Universal voltage (100-240V, 50/60Hz) with over-current protection; DC12V option for mobile use .
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GLP Compliance: Programmable protocols support GLP documentation; USB interface for data export and traceability .
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Temperature Calibration: Built-in self-calibration function ensures long-term accuracy; supports user recalibration for quality management .
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Portability Certification: Lightweight (≤1 kg) and compact design for point-of-care, field, and mobile laboratory applications .
5. STORAGE & HANDLING ATTRIBUTES
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Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation; ambient temperature 10-40°C, relative humidity <80% RH .
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Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.
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Block Maintenance: Remove and clean heating block with mild detergent; dry thoroughly before reinstallation; compatible with 7 interchangeable block types .
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Inspection: Inspect block contacts for residue or damage before each use; clean if needed.
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Calibration: Perform periodic temperature calibration using built-in user recalibration function; calibration support for quality management .
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Data Export: Use USB interface to export temperature and time data for quality records .
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Power Cord: Inspect power cord for damage before each use; DC12V option available for field use .
6. LABORATORY & CLINICAL APPLICATIONS
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Primary Application: Precise temperature-controlled sample preparation for molecular diagnostics (nucleic acid extraction, PCR preparation, DNA denaturation, enzyme preservation), clinical chemistry (enzyme assays, serum coagulation, sample warming), and general laboratory workflows requiring both heating and cooling capabilities .
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Clinical Role: Essential sample preparation equipment in clinical diagnostic laboratories, hospital molecular diagnostics labs, physician office laboratories, blood banks, point-of-care testing sites, field research stations, and veterinary diagnostic laboratories.
SAFETY HANDLING PRECAUTIONS
1. SAFETY PRECAUTIONS
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Temperature Setting: Do not exceed recommended temperatures for specific sample types; excessive heat may denature proteins or degrade analytes; use caution when setting temperatures above 95°C.
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Block Installation: Ensure heating block is properly seated before operation; use compatible blocks only for specific tube formats .
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Temperature Verification: Allow unit to reach set temperature before loading temperature-sensitive samples; verify temperature stability before use; built-in calibration support available .
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Hot and Cold Surface Warning: Heating block and lid may become hot during heating operation or cold during cooling operation; use appropriate handling precautions.
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Power Supply: Use appropriate power supply (100-240V AC or DC12V as specified); DC12V option suitable for vehicle or field use .
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Cleaning: Clean spills immediately; disinfect heating block if biological materials are involved; allow block to return to safe temperature before removal.
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Placement: Place on firm, flat, level, heat-resistant surface; ensure adequate clearance around unit for ventilation.
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Training: Only trained laboratory personnel should operate the MiniHC 100 for clinical diagnostic applications.
2. FIRST AID MEASURES
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Burn/Scald: If hot heating block or surface contacts skin, cool affected area immediately with cool running water for at least 15 minutes; seek medical attention for severe burns.
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Cold Injury: If cold surface contacts skin during cooling operation, warm affected area gradually with lukewarm water; seek medical attention for prolonged exposure.
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Sample Spillage: If biological sample spills into unit, disconnect power, allow unit to return to safe temperature, disinfect area immediately with 70% ethanol or appropriate disinfectant.
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Electrical Malfunction: If unit shows signs of electrical malfunction, disconnect power immediately; do not attempt to operate; contact service personnel.
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Calibration Verification: If test results are inconsistent, perform temperature recalibration using built-in user calibration function before proceeding with diagnostic testing .
3. FIRE FIGHTING MEASURES
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Flammability: Plastic housing and electrical components may burn.
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Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
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Fire Response: Unplug unit immediately; do not use water on electrical fire.
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