Digital Dry Bath Single Block(HB105-S1)

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The Digital Dry Bath Single Block(HB105-S1) is a compact, single-block benchtop dry thermostat designed for precise temperature-controlled incubation in clinical diagnostic, molecular biology, and research laboratories . With a temperature range from room temperature +5°C to 105°C and temperature control accuracy of ±0.5°C, this dry bath provides consistent, uniform heating for a wide range of diagnostic and research applications .
The HB105-S1 features a microprocessor-controlled system with LED display for real-time temperature and time monitoring, an intuitive control knob for simple operation without complex menus, and interchangeable aluminum heating blocks compatible with various tube formats and sizes . The unit supports both timing mode (0 to 99 hours 59 minutes) and continuous operation mode, with built-in temperature self-calibration function for long-term accuracy .
For the clinical laboratory scientist and medical technologist, the HB105-S1 supports enzyme-substrate reactions for biochemical tests and clinical chemistry, serum inactivation (56°C) for immunoassays and serological testing, DNA denaturation for nucleic acid amplification and PCR preparation, and sample warming and reagent thawing for diagnostic testing . The compact, single-block design is ideal for space-constrained laboratories while delivering reliable heating performance .
Safety features include over-temperature protection and an insulated lid that prevents heat loss and contamination . For the patient undergoing diagnostic testing for infectious diseases, autoimmune disorders, or genetic conditions, the HB105-S1’s precise temperature control ensures reliable enzyme reaction conditions, consistent DNA denaturation, and accurate sample preparation—supporting reliable test results that guide appropriate treatment decisions across clinical chemistry, molecular diagnostics, and research applications .
Description

Digital Dry Bath Single Block(HB105-S1)

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Enzyme Reaction and Biochemical Test Incubation
  • Primary Use: Provides a single-block digital dry bath with a temperature range from room temperature +5°C to 105°C, designed for precise incubation of enzyme-substrate reactions and biochemical assays in clinical and research laboratories.
  • How it helps: For the clinical chemist and medical technologist, the HB105-S1 delivers precise temperature control with LED display and user-friendly setting knob, ensuring consistent conditions for enzymatic assays—critical for accurate liver function tests (ALT, AST), cardiac biomarkers, and other enzyme-based diagnostic tests . For the patient, reliable enzymatic assay results enable accurate diagnosis of myocardial infarction, hepatitis, and other conditions requiring enzyme level monitoring.
2. Serum Inactivation and Complement Fixation
  • Primary Use: Used for serum inactivation protocols (typically at 56°C) and complement fixation tests in diagnostic immunology, utilizing the HB105-S1’s precise temperature control up to 105°C.
  • How it helps: For the clinical laboratory scientist, the HB105-S1 provides stable, uniform heating for serum complement inactivation—a critical step in immunoassays, serological testing for infectious diseases, and autoantibody screening . For the patient, proper serum inactivation ensures accurate antibody detection in infectious disease testing and autoimmune disorder diagnosis.
3. DNA Denaturation and Nucleic Acid Amplification
  • Primary Use: Provides controlled high-temperature heating for DNA denaturation steps in PCR preparation, nucleic acid amplification protocols, and molecular diagnostic workflows.
  • How it helps: For the molecular biologist, the HB105-S1’s precise temperature control (up to 105°C) and excellent temperature uniformity ensures consistent denaturation of double-stranded DNA—critical for PCR, sequencing, and hybridization-based assays . This supports accurate genetic testing for infectious diseases, inherited disorders, and oncology biomarkers. For the patient undergoing genetic testing, reliable denaturation supports accurate PCR results and appropriate treatment decisions.
4. Sample Preparation and Reagent Thawing
  • Primary Use: Used for controlled thawing of frozen clinical specimens and gentle warming of reagents to operating temperature before diagnostic testing .
  • How it helps: For the medical technologist, the HB105-S1 provides uniform, gentle heating that preserves sample integrity—preventing hemolysis, protein denaturation, and analyte degradation that can occur with rapid or uneven heating . For the patient, proper sample handling reduces the need for repeat specimen collection due to degraded samples, saving time and discomfort.

SECONDARY & SUPPORTIVE USES

1. ELISA and Immunoassay Incubation: Provides precise temperature control for enzyme-linked immunosorbent assay (ELISA) incubation steps in infectious disease and autoimmune testing.
2. Protein Denaturation and Purification: Used for protein denaturation steps in Western blotting, SDS-PAGE, and protein purification workflows.
3. Nucleic Acid Extraction and Purification: Supports heating steps in spin column-based DNA/RNA extraction protocols for molecular diagnostics.
4. Lipid and Cholesterol Analysis: Used for warming samples and reagents in lipid profiling and cholesterol fractionation protocols.
5. Endocrine and Hormone Assay Preparation: Supports temperature-controlled incubation for thyroid function tests, reproductive hormone panels, and endocrine assays.
6.  Coagulation Testing Sample Warming: Used for warming plasma samples and reagents for PT (Prothrombin Time) and PTT (Partial Thromboplastin Time) coagulation studies.
7. Therapeutic Drug Monitoring: Used for warming samples and reagents in therapeutic drug monitoring and toxicology screening.
8. Blood Bank and Transfusion Medicine: Supports temperature-controlled processing of blood components and compatibility testing samples.
9. Histology and Pathology Tissue Processing: Used for warming embedding media and processing solutions in histology laboratories.
10. Microbiology Culture Media Warming: Warms culture media to specified temperatures before inoculation in clinical microbiology workflows.
11. Pharmaceutical Quality Control: Used for stability testing and sample preparation in pharmaceutical QC laboratories.
12. Food Safety and Environmental Testing: Used for sample preparation and media warming in food microbiology and water quality testing.
13. Research and Academic Laboratories: Supports general laboratory incubation needs requiring precise temperature control.
14. Veterinary Diagnostic Laboratory: Supports clinical chemistry and molecular biology workflows for animal health testing.
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: A single-block digital dry bath with LED display, designed for precise temperature-controlled incubation in clinical diagnostics, molecular biology, and research laboratories .
  • Designation: HB105-S1 Digital Dry Bath, Single Block Dry Bath, Digital Dry Bath Incubator, DLAB HB105-S1, Single Block Heating Thermostat .
  • Key Components:
    • Heating Block: Interchangeable aluminum block compatible with various tube sizes and formats .
    • Microprocessor Controller: Regulates temperature with automatic feedback for precise control .
    • LED Display: Digital display for real-time temperature and time monitoring .
    • Control Knob: User-friendly setting knob for simple operation .
    • Insulated Lid: Lid for heat preservation, temperature stability, and contamination prevention .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • Temperature Range: Room temperature +5°C to 105°C .
  • Temperature Control Accuracy: ±0.5°C (at 20-45°C) .
  • Temperature Uniformity: ±0.2°C to ±0.5°C (max. ±0.5°C) .
  • Temperature Setting Display: Three-digit LED display with 0.1°C resolution .
  • Time Setting Range: 0 minutes to 99 hours 59 minutes .
  • Work Mode: Timing or continuous operation .
  • Heating Power: 160W .
  • Voltage/Frequency: 100-240V, 50/60Hz .
  • Dimensions (W × D × H): Compact benchtop footprint .
  • Weight: Lightweight design for benchtop use .
  • Calibration: Built-in temperature self-calibration function .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Construction: Single-block design for space-saving benchtop placement; durable outer housing.
  • Control System: Microprocessor-controlled with LED digital display .
  • Operation Modes: Timing mode (0-99h59min) and continuous operation mode .
  • Block Compatibility: Accepts various optional interchangeable heating blocks for different tube formats .
  • Calibration: Built-in temperature calibration function .
  • Safety Features: Over-temperature protection .
  • User Interface: Intuitive control knob for easy operation without complex menus .
  • Portability: Compact, single-block design ideal for space-constrained laboratories.
  • Maintenance: Simple cleaning; interchangeable blocks require no tools.

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Class I medical device for clinical diagnostic use .
  • Safety Features: Over-temperature protection system, lid for heat preservation and contamination prevention .
  • Electrical Safety: Universal voltage (100-240V, 50/60Hz); over-current protection; reverse voltage protection .
  • GLP Compliance: Timer and temperature display support GLP documentation .
  • Temperature Calibration: Built-in self-calibration function ensures long-term accuracy .

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store on clean, dry benchtop; ensure adequate clearance for ventilation.
  • Cleaning: Wipe exterior with soft, damp cloth using neutral detergent; 70% ethanol solution may be used for surface sterilization.
  • Block Maintenance: Remove and clean heating block with mild detergent; dry thoroughly before reinstallation.
  • Inspection: Inspect block contacts for residue or damage before each use; clean if needed.
  • Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination.
  • Calibration: Perform periodic temperature calibration per manufacturer guidelines.
  • Power Cord: Inspect power cord for damage before each use.

6. LABORATORY & CLINICAL APPLICATIONS

  • Primary Application: Enzyme reaction incubation, serum inactivation, DNA denaturation, sample preparation, and reagent warming in clinical diagnostic, molecular biology, and research laboratories.
  • Clinical Role: Essential sample preparation and incubation equipment in clinical diagnostic laboratories, hospital laboratories, physician office laboratories, blood banks, molecular diagnostics labs, and research facilities.
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Temperature Setting: Do not exceed recommended temperatures for specific sample types; excessive heat may denature proteins or degrade analytes.
  • Block Installation: Ensure heating block is properly seated before operation.
  • Temperature Verification: Allow unit to reach set temperature before loading temperature-sensitive samples.
  • Lid Use: Always use lid during operation to maintain temperature stability and prevent contamination.
  • Over-temperature Protection: Do not operate unit without proper ventilation.
  • Cleaning: Clean spills immediately; disinfect heating block if biological materials are involved; allow block to cool before removal.
  • Placement: Place on firm, flat, level, heat-resistant surface; ensure adequate clearance around unit for ventilation.
  • Training: Only trained laboratory personnel should operate the HB105-S1 for clinical diagnostic applications.

2. FIRST AID MEASURES

  • Burn/Scald: If hot heating block contacts skin, cool affected area immediately with cool running water for at least 15 minutes; seek medical attention for severe burns.
  • Sample Spillage: If biological sample spills into unit, disconnect power, allow to cool, disinfect area immediately with 70% ethanol or appropriate disinfectant.
  • Electrical Malfunction: If unit shows signs of electrical malfunction, disconnect power immediately; do not attempt to operate; contact service personnel.
  • Calibration Verification: If test results are inconsistent, perform temperature calibration to verify accuracy before proceeding with diagnostic testing.

3. FIRE FIGHTING MEASURES

  • Flammability: Plastic housing and electrical components may burn.
  • Extinguishing Media: Use carbon dioxide or dry chemical extinguisher for electrical fires.
  • Fire Response: Unplug unit immediately; do not use water on electrical fire.