Two-piece ostomy bag - Convex ostomy baseplate Amaris Medical
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Two-piece ostomy bag – Convex ostomy baseplate

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A Two-piece ostomy bag – Convex ostomy baseplate is a non-sterile, single-use skin barrier (flange/wafer) that is part of a two-piece ostomy system, designed with a curved (convex) surface specifically for patients with flush or retracted stomas or uneven peristomal skin contours . This convex baseplate adheres to the peristomal skin and provides a mechanical coupling (flex coupling or guided coupling) for attaching a separate ostomy pouch .
The convex shape applies gentle pressure to the peristomal area, helping to push the stoma outward while flattening skin folds and creases—problems that affect approximately 15-30% of ostomates and account for over 40% of visits to enterostomal therapy nurses . By creating a tighter seal, the convex baseplate prevents the leakage of corrosive digestive enzymes and liquid effluent onto the peristomal skin, which can otherwise cause faecal dermatitis, ulceration, hypergranulation, and severe pain .
Available in multiple convexity depths—soft convexity (gentle support with integrated flexlines for flexibility), light convexity (adaptive convex shell), and medium convexity (6mm depth for flush or retracted stomas)—the convex baseplate can be tailored to individual patient needs . The cut-to-fit design allows the opening to be trimmed to match stomas from 10mm to 53mm across flange diameters of 35mm, 45mm, 50mm, 55mm, 65mm, and 70mm . Many products feature BodyFit Technology® with elastic adhesive that stretches and retracts with the skin, and integrated flexlines that provide a unique combination of stability and flexibility .
The two-piece design allows the convex baseplate to remain in place for 2-3 days while pouches are changed as needed—particularly important for patients with high-output stomas who need to change their pouch multiple times daily. The mechanical coupling with floating flange allows pouch attachment without applying pressure to the abdomen, with an audible “click” confirming secure locking .
For the surgeon and stoma care nurse, the convex baseplate is a critical tool for managing challenging stoma anatomies where flat baseplates fail. For the patient with a flush or retracted stoma, this appliance provides the security, skin protection, and confidence needed to participate fully in daily activities—work, school, swimming, sports, and travel—without fear of leakage or pouch detachment, significantly improving quality of life and preventing the painful complications of peristomal skin breakdown.
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Description

Two-piece ostomy bag – Convex ostomy baseplate

PRIMARY CLINICAL & DIAGNOSTIC USES

1. Management of Flush or Retracted Stomas with Peristomal Skin Folds
  • Primary Use: Provides a non-sterile, single-use skin barrier with a curved (convex) surface designed to be applied and adhered to peristomal skin to facilitate correct positioning and anchorage of the flange of an intestinal ostomy bag . The convexity is specifically engineered for flush stomas (those level with the skin) or retracted stomas (those sunk below skin level) where the peristomal skin is uneven or has wrinkles and folds .
  • How it helps: For the surgeon and stoma care nurse, the convex baseplate addresses the challenge of stomas located within abdominal creases or uneven skin contours—conditions where flat baseplates fail to maintain a seal, leading to leakage and skin breakdown . The convex shape applies gentle pressure to the peristomal area, helping to push the stoma outward while flattening skin folds, which improves appliance adherence and significantly reduces leakage . For the patient with a challenging stoma anatomy (approximately 15-30% of ostomates), the convex baseplate provides the security and confidence that a flat baseplate cannot offer, preventing the painful cycle of leakage, skin irritation, and product failure.
2. Protection of Peristomal Skin from Digestive Enzymes and Effluent
  • Primary Use: The convex baseplate creates a tighter seal around the stoma to prevent leakage of corrosive digestive enzymes and liquid effluent onto the peristomal skin, which can cause faecal dermatitis, contact irritant dermatitis, and peristomal moisture-associated dermatitis (MASD) .
  • How it helps: For the wound ostomy and continence nurse (WOCN), convex baseplates are a critical intervention for patients with peristomal skin complications. Effluent from ileostomies contains proteolytic and lipolytic enzymes that damage both protein and lipid-based elements of the skin’s barrier, leading to denudation, ulceration, and granuloma formation . By creating a secure seal that fills in skin depressions, convexity prevents the effluent from pooling under the baseplate. For the patient, this protection prevents the burning pain, bleeding, and hypergranulation tissue that can develop when skin is constantly exposed to digestive enzymes—complications that affect up to 70% of ostomy patients and are a leading cause of emergency department visits .
3. Secure Two-Piece Coupling for Pouch Changes Without Skin Manipulation
  • Primary Use: Features a mechanical coupling system (flex coupling or guided coupling) that allows ostomy pouches to be attached and removed without disturbing the adhered baseplate. The floating flange design allows the pouch to be pressed onto the baseplate without applying direct pressure to the area around the stoma .
  • How it helps: For the clinician and patient, the two-piece design with convex baseplate offers significant advantages over one-piece systems. The baseplate remains in place for 2-3 days (standard wear) while pouches can be changed as needed—particularly important for patients with high-output stomas who may need to change their pouch multiple times daily. The audible “click” of the mechanical coupling confirms secure locking, and the floating flange prevents uncomfortable pressure on the stoma during attachment . For the patient, this design reduces skin trauma from repeated full appliance changes, lowers supply costs, and provides greater flexibility in managing their stoma across different activities and output patterns.
4. Customizable Fit with Cut-to-Fit Convex Technology
  • Primary Use: The convex baseplate features a cut-to-fit design, allowing the clinician or patient to trim the hydrocolloid opening to match the exact size and shape of the individual stoma. Available in various flange diameters (35mm, 45mm, 50mm, 55mm, 65mm, 70mm) with specific cut-to-fit ranges (e.g., 15-40mm, 15-53mm) to accommodate different stoma sizes .
  • How it helps: For the stoma care nurse and patient, the ability to customize the opening ensures a precise fit around the stoma—no larger than 1-2mm. An opening that is too large would expose peristomal skin to corrosive effluent, while an opening that is too tight could constrict the stoma and cause injury. The convexity itself is achieved through different technologies: some products use an adaptive convex shell with integrated flexlines (soft convex) for gentle support, while others use a more rigid pre-cast convex unit (light/medium convex) for deeper convexity needs . For the patient, this customization allows for a secure, comfortable fit that adapts to stoma changes over time (post-operative swelling, weight fluctuations), reducing the frequency of product changes and improving long-term outcomes.

SECONDARY & SUPPORTIVE USES

1. Alternative to Flat Baseplates When Leakage Persists: Indicated when a patient has tried flat baseplates but continues to experience leakage, particularly when the stoma is located within an abdominal crease, skin fold, or wrinkle that prevents flat baseplate adhesion .
2. Gradual Introduction of Convexity with Soft and Light Options: Available in soft convexity (gentle support, immediate post-operative use) and light/medium convexity (more pronounced curve for deeper retraction) to provide the right solution for different clinical needs .
3. High-Output Stoma Management: Used for patients with high-output ileostomies who require frequent pouch changes; the two-piece design allows pouch changes without disturbing the convex baseplate seal, reducing skin trauma and preserving the convex seal .
4. Use with Ostomy Belts: Compatible with ostomy belts that clip onto the baseplate flange, providing additional security and support during physical activities, swimming, or for patients with challenging abdominal contours .
5. Extended Wear for Cost-Effective Management: The baseplate is designed to remain in place for 2-3 days (standard wear) while pouches are changed multiple times per day, reducing the number of full appliance changes, lowering material costs, and minimizing skin manipulation.
6. Integration with Night Drainage Systems: Compatible with drainable pouches that can be connected to overnight drainage bags, allowing patients with high-output ileostomies to sleep uninterrupted while the system manages continuous drainage.
7. Transparent Options for Clinical Assessment: Transparent convex baseplates are available for use in the immediate post-operative period, allowing clinicians to assess stoma health and output without removing the appliance.
8. Restoration of Peristomal Skin Integrity After Damage: Used as part of a wound care regimen to restore peristomal skin integrity after leakage has caused faecal dermatitis, ulceration, or hypergranulation, often in combination with stoma powders, skin protectants, and alginate dressings .
9. Use with Stoma Paste and Barrier Rings: Can be used in conjunction with stomahesive paste, barrier rings, and stoma powders to fill in uneven skin contours and create an even smoother seal around the stoma, particularly useful for patients with deep skin folds or creases .
10. Management of Parastomal Hernias: Convex baseplates are sometimes used to help manage parastomal hernias by providing additional support to the peristomal area, though clinical judgment is required to assess appropriate convexity depth.
11. Belt Fixation for Enhanced Security: Many convex baseplates feature slots for belt fixation, allowing the baseplate to be secured with an ostomy belt for added stability during physical activity or for patients with challenging body contours .
12. Compatibility with a Range of Pouches: The convex baseplate is designed to work with multiple pouch types from the same manufacturer system, including drainable pouches for ileostomies, closed pouches for colostomies with formed stool, and urostomy pouches with anti-backflow valves .
13. Pre-Operative Stoma Siting to Prevent Convexity Needs: Stoma care nurses use knowledge of convexity requirements to guide stoma siting pre-operatively, aiming to place the stoma away from skin folds, bony prominences, and scars to minimize the need for convex products post-operatively .
14. Elastic Adhesive for Body Movement: The convex baseplate features an elastic adhesive that stretches and retracts with the skin, providing a secure fit during body movement while maintaining the convex shape .
15. Full-Circle Filter Compatibility: When used with compatible pouches, the convex baseplate supports the full-circle filter technology that reduces ballooning by up to 61%, improving discretion and helping patients sleep better at night .
KEY PRODUCT FEATURES

1. BASIC IDENTIFICATION ATTRIBUTES

  • Device Type: A non-sterile, single-use skin barrier (baseplate/wafer) that is part of a two-piece ostomy system, designed with a convex surface to be applied and adhered to peristomal skin to facilitate correct positioning and anchorage of the flange of an intestinal ostomy bag . The convexity is used to improve peristomal skin contact of a flush stoma or recessed stoma .
  • Designation: Two-piece convex ostomy baseplate, convex skin barrier, convex flange, convex wafer, intestinal ostomy base plate with convexity, ostomy skin barrier convex.
  • Key Components:
    • Convex Element: A curved structure (soft adaptive shell or more rigid pre-cast unit) that provides the convex shape, applying gentle pressure to the peristomal area to help flush or retract stomas protrude .
    • Hydrocolloid Adhesive Layer: The skin-contacting layer made of gel-forming particles (e.g., carboxymethylcellulose, pectin, gelatin) that absorbs moisture, protects the skin, and is highly durable against liquid output .
    • Mechanical Coupling (Flange): A plastic ring (flex coupling or guided coupling) that snaps onto the matching ring on the ostomy pouch, providing a secure, audible lock .
    • Floating Ring: A feature that allows the pouch to be attached and removed without applying pressure to the abdomen, enhancing comfort .
    • Cut-to-Fit Membrane: The central area of the baseplate that can be trimmed with curved scissors to match the exact size and shape of the patient's stoma .
    • Integrated Flexlines: Flexlines integrated into the convex shell provide a unique combination of stability and flexibility, allowing the baseplate to adapt to body contours during movement .
    • Elastic Adhesive (BodyFit Technology): An elastic adhesive that stretches and retracts with the skin, ensuring secure body contact for protection and a flexible fit during movement .
    • Top Film/Backing Layer: A thermoplastic backing material that supports the adhesive and helps maintain the convex shape .

2. TECHNICAL & PERFORMANCE PROPERTIES

  • GMDN Term & Definition: Intestinal ostomy base plate, convex. A non-sterile device designed with a convex surface intended to be applied and adhered to peristomal skin to facilitate correct positioning and anchorage of the flange of an intestinal ostomy bag (i.e., one-piece or exchangeable two-piece/multiple piece) and to protect the area from bodily waste contaminants. The convexity of the device is used to improve peristomal skin contact of a flush stoma or more typically a recessed stoma. It is typically self-applied by the patient. This is a single-use device .
  • FDA Product Code: EXB (COLLECTOR, OSTOMY)
  • Convexity Depth: Available in multiple depths:
    • Soft Convexity: Gentle support; integrated flexlines provide unique combination of stability and flexibility; suitable for immediate post-operative use and shallow retraction .
    • Light Convexity: Adaptive convex shell; moderate pressure; for stomas that need support to protrude .
    • Medium Convexity (6mm): Designed for flush or slightly retracted stomas; provides sufficient level of pressure evenly spread out on the peristomal area .
  • Convex Element Material: Material which reacts to moisture (hydrophilic material that softens or changes characteristics when exposed to moisture), allowing for customization while maintaining convexity .
  • Skin Barrier Material: Medical-grade hydrocolloid adhesive; highly durable and resistant to liquid output; adherent to both dry and wet skin; natural rubber latex free.
  • Flange Diameters: Available in multiple sizes including 35mm, 45mm, 50mm, 55mm, 65mm, and 70mm .
  • Cut-to-Fit Ranges:
    • 35mm flange: cut to 10-20mm or 18-20mm stoma opening 
    • 45mm flange: cut to 15-26mm stoma opening 
    • 50mm flange: cut to 15-40mm, 21-30mm, 25-30mm, 28-30mm, 31-40mm, 35-40mm 
    • 55mm flange: cut to 15-36mm stoma opening 
    • 65mm flange: cut to 15-46mm stoma opening 
    • 70mm flange: cut to 15-53mm, 38-53mm, 41-53mm 
  • Coupling Type: Mechanical (flex coupling or guided coupling) with audible click confirmation; floating ring for pressure-free attachment; available with three different bag positions for optimal orientation .
  • Wear Time: Standard wear; designed to remain in place for 2-3 days, depending on output volume, stoma type, and skin condition.
  • Flexibility: Adaptive convex shell with integrated flexlines provides a unique combination of stability and flexibility; elastic adhesive ensures product can stretch and retract back with skin movement .
  • Belt Fixation: Slots for belt fixation available in three different positions on many models .
  • Sterility: Non-sterile; intended for use on clean, intact peristomal skin .
  • Single-Use: Intended for single patient use only.
  • Latex-Free: Manufactured without natural rubber latex to accommodate patients with latex allergies.
  • Quality Standards: Compliant with ISO 8670-2 (Ostomy collection bags) and ISO 12505 (Skin barrier for ostomy aids - Test methods). ISO/AWI 12505-3 specifically addresses test methods for characteristics of convex face plates of skin barriers for ostomy aids .

3. PHYSICAL & OPERATIONAL PROPERTIES

  • Configuration: Part of a two-piece system where the convex baseplate and pouch are separate components that are attached via a mechanical coupling.
  • Appearance: Opaque, beige, skin-toned, or grey fabric-textured wafer designed for discretion and to look more like a piece of clothing than a medical device . The grey colour is specifically chosen to optimize discretion under all clothing colours, even white .
  • Convex Shape: Curved (convex) surface that protrudes outward toward the skin, designed to fill in skin depressions and apply gentle pressure to the peristomal area.
  • Flexibility: Flexible design conforms to body shape and natural movements; integrated flexlines allow the convex shell to adapt to individual body contours .
  • Cutability: Cut-to-fit design allows the opening to be trimmed with curved scissors to match the exact stoma size and shape; the convex element material reacts to moisture, allowing for customization without compromising the convex shape .
  • Surface: The hydrocolloid adhesive is comfortable on the skin during wear and gentle upon removal; the textile material is soft against the skin and provides low friction against clothes .
  • Compatibility: Compatible with ostomy pouches from the same manufacturer system (drainable, closed, urostomy) .
  • Coupling Orientation: Many systems offer three different bag positions for optimal orientation and comfort .
  • Packaging: Typically supplied in boxes of 5 pieces .
  • Accessories: May be used with ostomy belts, paste, powder, and barrier rings.
  • Water Resistance: Water-repellent material that does not feel wet after showering .
  • Noise Reduction: Quiet material that does not rustle during movement .
  • Filter Compatibility: When used with compatible pouches, the full-circle filter reduces ballooning by up to 61% .

4. SAFETY & COMPLIANCE ATTRIBUTES

  • Regulatory Status: Class I medical device (FDA Product Code EXB - Collector, Ostomy).
  • Quality Standards: Complies with international ostomy standards; manufactured under quality management systems (ISO 13485). CE marked for the European market.
  • Biocompatibility: Manufactured with skin-friendly, hypoallergenic, non-irritating materials; the hydrocolloid barrier is free from natural rubber latex and common sensitizers.
  • Adhesion: Adherent to both dry and wet skin; highly durable and resistant to liquid output from ileostomies and urostomies.
  • Latex-Free: Manufactured without natural rubber latex to accommodate patients with latex allergies.
  • Pressure Safety: Convexity is designed to provide a sufficient level of pressure evenly spread out on the peristomal area to prevent pressure injury or ulceration . However, excessive convexity depth or prolonged use beyond recommended wear time may cause peristomal skin damage, including pressure wound ulceration, bruises, and general skin irritation .
  • Storage: Store in a cool, dry place (below 25°C / 77°F recommended). Avoid exposure to direct sunlight, extreme heat, or humidity, which can degrade the adhesive and convex element.
  • Expiration: Shelf life varies by manufacturer; check packaging for expiration date.

5. STORAGE & HANDLING ATTRIBUTES

  • Storage: Store in a cool, dry place at room temperature (below 25°C / 77°F recommended). Avoid exposure to direct sunlight, extreme heat, or humidity, which can degrade the adhesive and convex element. Keep out of reach of children.
  • Shelf Life: Check individual packaging for expiration date; typically 2-3 years from manufacture.
  • Skin Preparation: Peristomal skin must be clean, completely dry, and free of lotions, oils, powders, or adhesive residue before application to ensure proper adhesion. The convex baseplate should be considered when there are skin folds, wrinkles, or creases around the stoma that prevent flat baseplate adhesion .
  • Cutting Instructions: Use the provided stoma measuring guide to determine correct stoma size. Cut the opening no larger than 1-2 mm (1/16-1/8 inch) larger than the stoma. Use curved scissors for precise cutting. The convex element material reacts to moisture, allowing for customization without compromising the convex shape .
  • Application: Remove the protective liner. Center the opening over the stoma. Press the adhesive firmly onto the skin, smoothing from the stoma outward. Warm the baseplate with body heat before applying in cool environments. Ensure the convexity is properly positioned to fill in skin depressions.
  • Pouch Attachment: Align the coupling rings and press together until an audible "click" confirms secure locking. The floating ring allows attachment without abdominal pressure .
  • Pouch Removal: To remove the pouch, gently press the release tabs on the coupling ring. The convex baseplate remains adhered to the skin.
  • Baseplate Removal: Gently peel the baseplate from the skin, supporting the skin with the other hand. Adhesive remover wipes may be used to facilitate removal.
  • Disposal: Discard used baseplate in general waste per local regulations. Do not flush.

6. LABORATORY & CLINICAL APPLICATIONS

  • Primary Application: Management of intestinal or urinary effluent following ostomy surgery in patients with flush or retracted stomas, uneven peristomal skin contours, or skin folds/creases that prevent flat baseplate adhesion. The convexity improves peristomal skin contact and helps the stoma protrude, reducing leakage and protecting peristomal skin from corrosive effluent .
  • Clinical Role: Essential post-operative and long-term care device in colorectal surgery, urology, and home healthcare for the management of patients with challenging stoma anatomy (flush stomas, retracted stomas, stomas within skin folds) where flat baseplates have failed. Indicated for approximately 15-30% of ostomates who require convexity to maintain a secure seal .
SAFETY HANDLING PRECAUTIONS

1. SAFETY PRECAUTIONS

  • Indication for Use: Convex baseplates are indicated for patients with flush stomas (level with the skin), retracted stomas (sunk below skin level), or peristomal skin folds/creases that prevent flat baseplate adhesion . They are NOT indicated for patients with well-protruding stomas on flat abdominal surfaces unless other indications exist.
  • Contraindications: Do not use it on patients with known hypersensitivity to hydrocolloid components or adhesive materials. Use with caution in patients with fragile peristomal skin, as excessive convexity depth may cause pressure injury .
  • Infected or Wounded Skin: Do not apply to infected, severely denuded, or wounded peristomal skin without appropriate medical evaluation and treatment.
  • Skin Preparation: Peristomal skin must be meticulously cleaned, dried, and free of lotions or barrier creams before application to ensure proper adhesion .
  • Customization: The opening must be cut to the exact size of the stoma (no larger than 1-2mm). An opening that is too large will expose fragile skin to corrosive effluent, leading to maceration, excoriation, and infection .
  • Monitor for Leaks: Inspect the convex baseplate frequently, especially in the early post-operative period. Change the appliance immediately if any effluent is observed leaking under the barrier to prevent skin damage.
  • Signs of Pressure Injury: The convex element applies pressure to the peristomal area. Monitor for signs of pressure injury, including redness that does not resolve after appliance removal, bruising, or skin breakdown. Discontinue use or reduce convexity depth if pressure injury occurs .
  • Signs of Skin Breakdown: Discontinue use and consult a stoma care nurse if the peristomal skin becomes red, weepy, raw, or itchy, indicating possible fungal infection (candidiasis), contact dermatitis, or adhesive allergy .
  • Proper Convexity Selection: Select the appropriate depth of convexity for the patient's anatomy—soft convexity for shallow retraction (immediate post-operative), light or medium convexity for deeper retraction. Using excessive convexity depth for a well-protruding stoma may cause pressure injury .
  • Adhesive Allergy: Patients with known adhesive sensitivities should use with caution; discontinue use if signs of allergic contact dermatitis (rash, itching, blistering, spreading redness) occur.
  • Output Consistency: For patients with very liquid output (ileostomy), convex baseplates with higher durability and resistance to enzymatic degradation are recommended. For high-output stomas, a convex baseplate combined with a high-output pouch may be required .
  • Stoma Protrusion: The convex baseplate is indicated for flush or retracted stomas (protrusion less than 1cm). For stomas with adequate protrusion (greater than 1.5cm), a flat baseplate is typically sufficient .
  • Do Not Reuse: This is a single-use device; do not attempt to wash, resterilize, or reapply a used baseplate.

2. FIRST AID MEASURES

  • Adhesive Allergy: If signs of an allergic reaction (rash, severe itching, blistering, redness spreading beyond the baseplate area) occur, remove the appliance immediately, gently cleanse the skin with mild soap and water, discontinue use of that product, and consult a clinician.
  • Peristomal Maceration and Ulceration: If the skin surrounding the stoma appears white, soft, or wrinkled (maceration) or has open ulcerations, remove the convex baseplate, allow the skin to dry, and consult a stoma care nurse. Consider an alternative convexity depth, cut-to-fit size, or flat baseplate after skin healing .
  • Pressure Injury: If the peristomal skin shows signs of pressure injury (non-blanchable redness, bruising, blistering, or open ulceration in a pattern matching the convex element), remove the convex baseplate immediately and consult a stoma care nurse. A shallower convexity depth or flat baseplate may be required .
  • Leakage: If a leak occurs, remove the appliance immediately, gently cleanse the skin with warm water (avoid soaps and wipes containing alcohol, oils, or fragrances), dry thoroughly, and apply a new convex baseplate and pouch.
  • Bleeding Stoma: If the stoma bleeds when cleaning or measuring (common due to high vascularity), apply gentle pressure with a clean, dry gauze pad for a few minutes. Contact a clinician if bleeding is profuse or does not stop.
  • Signs of Infection (Peristomal Skin): If the peristomal skin becomes increasingly red, swollen, warm, or produces purulent discharge, remove the convex baseplate, cleanse the skin, and seek medical evaluation, as this may indicate fungal or bacterial infection requiring treatment .
  • Hypergranulation Tissue: If raised, moist, bleeding granulomas develop around the stoma (indicating chronic irritation from leakage), remove the convex baseplate, consult a stoma care nurse. Treatment may include silver nitrate cautery, topical steroid creams, and ensuring a proper convexity fit to prevent further leakage .

3. FIRE FIGHTING MEASURES

  • Flammability: The plastic coupling, convex element, and hydrocolloid baseplate are combustible. Keep away from open flames and direct heat sources.
  • Extinguishing Media: Use water, foam, CO₂, or dry chemical for fires involving combustible material. The baseplate presents no special fire hazard beyond typical medical plastics.
  • Storage Warning: Do not store ostomy supplies near radiators, heating vents, or in vehicles during hot weather, as extreme heat can degrade the adhesive and convex element.

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Vacutainer (EDTA/PLAIN)

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Vacutainer (EDTA/PLAIN) is a sterile, evacuated blood collection tube (lavender/purple top) containing EDTA anticoagulant (K2EDTA or K3EDTA, 1.5-2.0 mg/mL blood) for hematology, blood banking, flow cytometry, and molecular diagnostics. Available in draw volumes 2-10 mL, glass or PET plastic, with color-coded stopper and sterile interior. EDTA chelates calcium, preventing coagulation while preserving cellular morphology. Primary clinical applications include complete blood count (CBC) and differential, blood typing and antibody screening (ABO/Rh, Coombs), hemoglobin A1c (HbA1c) testing, flow cytometry and immunophenotyping (CD4 counts), molecular diagnostics and PCR testing, sickle cell screening and hemoglobin electrophoresis, and parasitology (malaria smears). Critical safety precautions include filling to completion (correct blood-to-additive ratio), gentle inversion 8-10 times immediately after collection, never using for chemistry or coagulation testing, and proper disposal as biohazardous waste. Essential collection tube for hematology and immunohematology.
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